KEGG   Ehrlichia sennetsu: NSE_0500
Entry
NSE_0500          CDS       T00329                                 
Symbol
ligA
Name
(GenBank) DNA ligase, NAD-dependent
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
nse  Ehrlichia sennetsu
Pathway
nse03030  DNA replication
nse03410  Base excision repair
nse03420  Nucleotide excision repair
nse03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:nse00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    NSE_0500 (ligA)
   03410 Base excision repair
    NSE_0500 (ligA)
   03420 Nucleotide excision repair
    NSE_0500 (ligA)
   03430 Mismatch repair
    NSE_0500 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:nse03032]
    NSE_0500 (ligA)
   03400 DNA repair and recombination proteins [BR:nse03400]
    NSE_0500 (ligA)
Enzymes [BR:nse01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     NSE_0500 (ligA)
DNA replication proteins [BR:nse03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     NSE_0500 (ligA)
DNA repair and recombination proteins [BR:nse03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     NSE_0500 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     NSE_0500 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     NSE_0500 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      NSE_0500 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB BRCT HHH_2 DNA_ligase_ZBD BRCT_2 PTCB-BRCT HHH_5 5_3_exonuc Nlig-Ia
Other DBs
NCBI-ProteinID: ABD46192
UniProt: Q2GDR2
LinkDB
Position
complement(420546..422558)
AA seq 670 aa
MEAKKEIQELYEKLLRHNKKYYQDDSPEITDAEYDSIKDRYLKLLEANPSLGFPVVVGYP
ASEKFQKVKHLSPMLSLRNIFSEEELVEYIEKTKRFLNLKSALEFLCEPKIDGVSFSARY
VNGKLVSCATRGDGKIGENIIDNMKVINGFPIEIMDVPDLLEVRGEVFLDHDTFQTLEGF
SNPRNAAAGSLRQLNPEITNERNLQYFAYSASKIDGIEHQEDVLHFLSGRGFMTNPLRLA
SSKVPEIMSFYDSVYRRRSQIKYDIDGLVYKVNDLKLHARLGTLSDAPRWAIAHKFPSHR
AKTILEKIKLSVGRTGIITPVAHLKPITIGGVVISRASLYNEDELERKDIREGDLVIVER
AGDVIPKVLEVDISYRTNQERFIFPDKCPSCSSTLIRKNNEAATRCNNSKKCPEQVIQQI
KHLVSAQAFDIDGIGTSHISFFIEKGFISEPADIFRLDKHRDEIKKYDGWGEKSVENILK
NIKNSRKISLEKFIFSLGIKNIGEKTAYMLAQQFKSFANWFDKMSMLKDDTQTEDEIRNL
DGMGSCICESLLDFFSDSDNCNMVKSLSNHVMITDHTVNIGGSLSGKKFVFTGTLLSITR
EEAKEIIKKAGGIVVNSISKQIDYVVAGEKAGSKLAKANELGIAIIEEKTLIEFTNGNNT
PALKKETSSN
NT seq 2013 nt   +upstreamnt  +downstreamnt
atggaagcaaagaaggaaattcaagagctttacgagaagctcctacgacacaataagaag
tactatcaagatgatagtccagagataacagatgctgaatatgactcgattaaggaccgt
taccttaagcttctggaagcaaatccgagtctaggctttccggtagttgttggctaccct
gcttctgagaagtttcaaaaagtcaaacacctgtctcctatgctttcattacgcaacatc
ttctcggaagaagaactggtagagtatatcgaaaaaacaaaaagattccttaatctgaaa
agtgcacttgaattcctgtgtgaacccaaaatagatggtgtgtcattttctgcacgttat
gtcaacggaaaactagtctcttgtgcaacaagaggagatgggaaaataggagaaaacatt
attgataacatgaaagttatcaatggtttccccatagaaattatggatgtaccagatctt
ttggaagtacgtggagaagttttccttgaccatgatacttttcaaactcttgaaggcttt
tcaaatcctcggaatgctgctgcggggtcgcttaggcaacttaatcctgaaataacaaat
gaacgcaatctgcaatacttcgcttatagcgcgagcaaaatcgatggaatagaacatcaa
gaagatgtgttacactttctcagtgggcgtggttttatgacaaatccgttgagactagct
tcgtcaaaagttcctgaaatcatgagcttttacgattctgtttatcgtagacgctcgcaa
atcaagtacgatatagatgggctggtctacaaggtgaatgatctcaagttacatgcgagg
ctgggtacactatcagatgcacctagatgggccatagcgcataaatttccctcacatcga
gcaaagactatacttgaaaaaattaagctcagcgttgggcgtacaggtatcatcacgcca
gttgctcacttaaaaccaattaccataggcggagtcgttatatcaagggcgagcttatat
aacgaagacgaactagagagaaaagatatccgcgaaggagatctggtaatagtagaaaga
gctggagatgtaattccaaaagtgcttgaagtagacatctcgtatagaactaatcaggag
aggtttatctttcctgataaatgtccatcctgttcttctacactgataagaaaaaataac
gaagcggcgactcgatgcaataatagcaaaaaatgccccgaacaggtaatacaacaaata
aaacatcttgtctcagcgcaagcgttcgatatagatggtattgggacatcacacatctct
ttttttattgagaagggatttatttcagaaccagcagatatttttcgcttagataagcac
agagatgagatcaaaaaatatgatggttggggagagaaatcagtagagaatattcttaaa
aatattaaaaactctcggaaaataagtttggaaaaatttatttttagccttggaataaaa
aatataggcgaaaagactgcttacatgcttgcacaacagttcaaaagttttgccaactgg
tttgacaaaatgtccatgctcaaagacgatactcaaactgaggatgaaattaggaatctc
gatggtatgggaagttgtatctgtgaatctttactggattttttcagtgattcagataat
tgcaatatggtaaaaagtttatccaatcacgtcatgattactgatcacactgttaatata
ggtggctcacttagcgggaaaaaattcgtttttacaggcacgcttctctcaattactaga
gaagaagcaaaagagatcataaaaaaagccggtggtatagttgtgaacagtatttctaag
caaatcgactacgttgtagctggagaaaaagcgggctcaaaacttgcaaaagccaatgag
cttggtattgcaatcatagaagaaaaaaccctcatagaattcacaaatgggaacaacaca
cctgctcttaagaaagagacaagctccaactaa

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