KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110577152
Entry
110577152         CDS       T08474                                 
Symbol
BCL2
Name
(RefSeq) apoptosis regulator Bcl-2 isoform X1
  KO
K02161  apoptosis regulator Bcl-2
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu01521  EGFR tyrosine kinase inhibitor resistance
nsu01522  Endocrine resistance
nsu01524  Platinum drug resistance
nsu04064  NF-kappa B signaling pathway
nsu04066  HIF-1 signaling pathway
nsu04071  Sphingolipid signaling pathway
nsu04115  p53 signaling pathway
nsu04140  Autophagy - animal
nsu04141  Protein processing in endoplasmic reticulum
nsu04151  PI3K-Akt signaling pathway
nsu04210  Apoptosis
nsu04215  Apoptosis - multiple species
nsu04217  Necroptosis
nsu04261  Adrenergic signaling in cardiomyocytes
nsu04340  Hedgehog signaling pathway
nsu04510  Focal adhesion
nsu04621  NOD-like receptor signaling pathway
nsu04630  JAK-STAT signaling pathway
nsu04722  Neurotrophin signaling pathway
nsu04725  Cholinergic synapse
nsu04915  Estrogen signaling pathway
nsu04928  Parathyroid hormone synthesis, secretion and action
nsu04933  AGE-RAGE signaling pathway in diabetic complications
nsu05014  Amyotrophic lateral sclerosis
nsu05022  Pathways of neurodegeneration - multiple diseases
nsu05132  Salmonella infection
nsu05145  Toxoplasmosis
nsu05152  Tuberculosis
nsu05161  Hepatitis B
nsu05162  Measles
nsu05168  Herpes simplex virus 1 infection
nsu05169  Epstein-Barr virus infection
nsu05170  Human immunodeficiency virus 1 infection
nsu05200  Pathways in cancer
nsu05206  MicroRNAs in cancer
nsu05207  Chemical carcinogenesis - receptor activation
nsu05210  Colorectal cancer
nsu05215  Prostate cancer
nsu05222  Small cell lung cancer
nsu05226  Gastric cancer
nsu05417  Lipid and atherosclerosis
nsu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    110577152 (BCL2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    110577152 (BCL2)
   04630 JAK-STAT signaling pathway
    110577152 (BCL2)
   04064 NF-kappa B signaling pathway
    110577152 (BCL2)
   04066 HIF-1 signaling pathway
    110577152 (BCL2)
   04071 Sphingolipid signaling pathway
    110577152 (BCL2)
   04151 PI3K-Akt signaling pathway
    110577152 (BCL2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110577152 (BCL2)
  09143 Cell growth and death
   04210 Apoptosis
    110577152 (BCL2)
   04215 Apoptosis - multiple species
    110577152 (BCL2)
   04217 Necroptosis
    110577152 (BCL2)
   04115 p53 signaling pathway
    110577152 (BCL2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    110577152 (BCL2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    110577152 (BCL2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    110577152 (BCL2)
   04928 Parathyroid hormone synthesis, secretion and action
    110577152 (BCL2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110577152 (BCL2)
  09156 Nervous system
   04725 Cholinergic synapse
    110577152 (BCL2)
   04722 Neurotrophin signaling pathway
    110577152 (BCL2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110577152 (BCL2)
   05206 MicroRNAs in cancer
    110577152 (BCL2)
   05207 Chemical carcinogenesis - receptor activation
    110577152 (BCL2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    110577152 (BCL2)
   05226 Gastric cancer
    110577152 (BCL2)
   05215 Prostate cancer
    110577152 (BCL2)
   05222 Small cell lung cancer
    110577152 (BCL2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110577152 (BCL2)
   05161 Hepatitis B
    110577152 (BCL2)
   05162 Measles
    110577152 (BCL2)
   05168 Herpes simplex virus 1 infection
    110577152 (BCL2)
   05169 Epstein-Barr virus infection
    110577152 (BCL2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    110577152 (BCL2)
   05152 Tuberculosis
    110577152 (BCL2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110577152 (BCL2)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    110577152 (BCL2)
   05022 Pathways of neurodegeneration - multiple diseases
    110577152 (BCL2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110577152 (BCL2)
   05418 Fluid shear stress and atherosclerosis
    110577152 (BCL2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    110577152 (BCL2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    110577152 (BCL2)
   01524 Platinum drug resistance
    110577152 (BCL2)
   01522 Endocrine resistance
    110577152 (BCL2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:nsu01009]
    110577152 (BCL2)
Protein phosphatases and associated proteins [BR:nsu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     110577152 (BCL2)
SSDB
Motif
Pfam: Bcl-2 BH4 Bcl-2_3 ARMH5
Other DBs
NCBI-GeneID: 110577152
NCBI-ProteinID: XP_021542076
UniProt: A0A2Y9GS51
LinkDB
Position
14:13171689..13336479
AA seq 234 aa
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDAGAAPPGATPAPGIYSSQPGRTPAPA
RTSPPLPPAAPAAAAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFT
ARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHL
HTWIQDNGGWDAFVELYGPSMQPLFDFSWLSLKALLSLALVGACITLGAYLGHK
NT seq 705 nt   +upstreamnt  +downstreamnt
atggcgcacgctgggagaacagggtatgacaaccgggagatagtgatgaagtacatccac
tataagctgtcgcagaggggctacgagtgggacgccggagacgcgggcgccgcgcccccg
ggggccacccccgcgccgggcatctactcctcgcagcccgggcgcacccccgcgcccgcc
aggacctcgccgccgctgcccccggccgcccccgccgccgccgccgccgcgggccctgcg
ctcagccccgtgccacctgtggtccacctgaccctgcgccaggcgggcgacgacttctcc
cgtcgctaccgccgcgacttcgcggagatgtccagccagctgcacctgacacccttcacc
gcaaggggacgctttgccacggtggtggaggagctcttcagggatggggtaaactggggg
aggatcgtggccttctttgagttcggtggggtcatgtgtgtggagagcgtcaaccgggag
atgtcgcccctggtggacaacatcgctctgtggatgactgagtacctgaaccggcacttg
cacacctggatccaggacaacggaggctgggatgcctttgtggagctgtatggccccagc
atgcagcctctgtttgacttctcctggctgtctctgaaggcccttctcagtctggccctg
gtgggagcttgcatcaccctgggtgcctacctgggccacaagtga

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