Neomonachus schauinslandi (Hawaiian monk seal): 110578940
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Entry
110578940 CDS
T08474
Symbol
ADCY8
Name
(RefSeq) adenylate cyclase type 8
KO
K08048
adenylate cyclase 8 [EC:
4.6.1.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00230
Purine metabolism
nsu01100
Metabolic pathways
nsu01522
Endocrine resistance
nsu04015
Rap1 signaling pathway
nsu04020
Calcium signaling pathway
nsu04022
cGMP-PKG signaling pathway
nsu04024
cAMP signaling pathway
nsu04062
Chemokine signaling pathway
nsu04072
Phospholipase D signaling pathway
nsu04081
Hormone signaling
nsu04082
Neuroactive ligand signaling
nsu04114
Oocyte meiosis
nsu04211
Longevity regulating pathway
nsu04213
Longevity regulating pathway - multiple species
nsu04261
Adrenergic signaling in cardiomyocytes
nsu04270
Vascular smooth muscle contraction
nsu04371
Apelin signaling pathway
nsu04540
Gap junction
nsu04611
Platelet activation
nsu04713
Circadian entrainment
nsu04714
Thermogenesis
nsu04720
Long-term potentiation
nsu04723
Retrograde endocannabinoid signaling
nsu04724
Glutamatergic synapse
nsu04725
Cholinergic synapse
nsu04727
GABAergic synapse
nsu04742
Taste transduction
nsu04750
Inflammatory mediator regulation of TRP channels
nsu04911
Insulin secretion
nsu04912
GnRH signaling pathway
nsu04913
Ovarian steroidogenesis
nsu04914
Progesterone-mediated oocyte maturation
nsu04915
Estrogen signaling pathway
nsu04916
Melanogenesis
nsu04918
Thyroid hormone synthesis
nsu04921
Oxytocin signaling pathway
nsu04923
Regulation of lipolysis in adipocytes
nsu04925
Aldosterone synthesis and secretion
nsu04926
Relaxin signaling pathway
nsu04927
Cortisol synthesis and secretion
nsu04928
Parathyroid hormone synthesis, secretion and action
nsu04934
Cushing syndrome
nsu04935
Growth hormone synthesis, secretion and action
nsu04970
Salivary secretion
nsu04971
Gastric acid secretion
nsu04972
Pancreatic secretion
nsu04976
Bile secretion
nsu05032
Morphine addiction
nsu05163
Human cytomegalovirus infection
nsu05166
Human T-cell leukemia virus 1 infection
nsu05200
Pathways in cancer
nsu05207
Chemical carcinogenesis - receptor activation
nsu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110578940 (ADCY8)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
110578940 (ADCY8)
04371 Apelin signaling pathway
110578940 (ADCY8)
04020 Calcium signaling pathway
110578940 (ADCY8)
04072 Phospholipase D signaling pathway
110578940 (ADCY8)
04024 cAMP signaling pathway
110578940 (ADCY8)
04022 cGMP-PKG signaling pathway
110578940 (ADCY8)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
110578940 (ADCY8)
04081 Hormone signaling
110578940 (ADCY8)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
110578940 (ADCY8)
09144 Cellular community - eukaryotes
04540 Gap junction
110578940 (ADCY8)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110578940 (ADCY8)
04062 Chemokine signaling pathway
110578940 (ADCY8)
09152 Endocrine system
04911 Insulin secretion
110578940 (ADCY8)
04923 Regulation of lipolysis in adipocytes
110578940 (ADCY8)
04912 GnRH signaling pathway
110578940 (ADCY8)
04913 Ovarian steroidogenesis
110578940 (ADCY8)
04915 Estrogen signaling pathway
110578940 (ADCY8)
04914 Progesterone-mediated oocyte maturation
110578940 (ADCY8)
04921 Oxytocin signaling pathway
110578940 (ADCY8)
04926 Relaxin signaling pathway
110578940 (ADCY8)
04935 Growth hormone synthesis, secretion and action
110578940 (ADCY8)
04918 Thyroid hormone synthesis
110578940 (ADCY8)
04928 Parathyroid hormone synthesis, secretion and action
110578940 (ADCY8)
04916 Melanogenesis
110578940 (ADCY8)
04925 Aldosterone synthesis and secretion
110578940 (ADCY8)
04927 Cortisol synthesis and secretion
110578940 (ADCY8)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
110578940 (ADCY8)
04270 Vascular smooth muscle contraction
110578940 (ADCY8)
09154 Digestive system
04970 Salivary secretion
110578940 (ADCY8)
04971 Gastric acid secretion
110578940 (ADCY8)
04972 Pancreatic secretion
110578940 (ADCY8)
04976 Bile secretion
110578940 (ADCY8)
09156 Nervous system
04724 Glutamatergic synapse
110578940 (ADCY8)
04727 GABAergic synapse
110578940 (ADCY8)
04725 Cholinergic synapse
110578940 (ADCY8)
04720 Long-term potentiation
110578940 (ADCY8)
04723 Retrograde endocannabinoid signaling
110578940 (ADCY8)
09157 Sensory system
04742 Taste transduction
110578940 (ADCY8)
04750 Inflammatory mediator regulation of TRP channels
110578940 (ADCY8)
09149 Aging
04211 Longevity regulating pathway
110578940 (ADCY8)
04213 Longevity regulating pathway - multiple species
110578940 (ADCY8)
09159 Environmental adaptation
04713 Circadian entrainment
110578940 (ADCY8)
04714 Thermogenesis
110578940 (ADCY8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110578940 (ADCY8)
05207 Chemical carcinogenesis - receptor activation
110578940 (ADCY8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110578940 (ADCY8)
05163 Human cytomegalovirus infection
110578940 (ADCY8)
09165 Substance dependence
05032 Morphine addiction
110578940 (ADCY8)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
110578940 (ADCY8)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
110578940 (ADCY8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
110578940 (ADCY8)
Enzymes [BR:
nsu01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
110578940 (ADCY8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
AC_N
Adcy_cons_dom
TBK1_ULD
Motif
Other DBs
NCBI-GeneID:
110578940
NCBI-ProteinID:
XP_021544139
UniProt:
A0A2Y9H4F5
LinkDB
All DBs
Position
4:complement(177158602..177418161)
Genome browser
AA seq
1250 aa
AA seq
DB search
MELSDVRCLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGSSGG
SGSRGSGKASDPAGGGPNHHAAQLSGASAPPLYSLGPGERAHSTGGTKVFPERSGSGSGG
GGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKS
EVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTY
LQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSL
LQVVLQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARL
RLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVK
GFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHC
CVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLE
SGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDI
VKESVSSSDGRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQ
SGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFI
VLLFITAIQSLLPSSRVMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINET
YLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGV
LAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEAS
LLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVAR
HFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDEL
LGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHS
FNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILK
DQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQ
SLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPSGPEPGAQAEGTDKSDLP
NT seq
3753 nt
NT seq
+upstream
nt +downstream
nt
atggagctctccgatgtgcgctgcctgagcggcagcgaggaactctacactatccacccg
acgcccccggccggcgacggcgggagcggctcgcggccgcagcggctgttgtggcagacg
gcggtgaggcacatcaccgagcagcgcttcattcatgggcaccggggcagcagcggcggc
agcgggagcagaggctccggcaaagcctcggaccctgcaggcggcggccccaaccatcac
gcggcgcagctgtccggcgcctcggcgccgcccctctactcgctgggccccggggagaga
gcgcacagcactggtggcaccaaagtcttcccggaacgcagcgggagcggcagcggcggc
gggggcgggggcgatctgggcttcctgcacctcgactgcgccccaagcaactcggatttc
ttcctcaatgggggctatagctaccgaggggtcattttccccactctgcgcaactccttc
aagtcccgggatctggagcgcctctaccagcgctatttcctgggccagaggcgcaaatcc
gaggtggtgatgaacgtgctggacgtgctgaccaaactcaccctcttggtcctccacttg
agcctggcctcggcccccatggacccgctcaagggcatcctcctgggcttcttcactggc
atcgaggtggtgatctgcgccctggtggtggtcaggaaggacaccacctcgcacacgtac
ctgcagtacagcggcgtggtcacttgggtggctatgaccacccagatcttggcagcaggc
ctcggctacgggcttctgggtgatggcatcggctacgttctcttcacgctgtttgccacc
tacagcatgctgccgctgccgctcacctgggccatcctggccggcctgggcacctcgctg
ctgcaggtggtcctgcaggtggtcatccctcggctagcggtcatttccatcaaccaggtt
gtggcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatcagctacctg
tcagaccgggcccagcgccaagccttcctggagacgcggaggtgtgtggaggccaggcta
cgcctggagacggaaaaccaaagacaggagcggctcgtgctatctgtgctcccccgcttt
gtcgtcctggaaatgatcaacgacatgaccaatgttgaagacgagcacttgcagcaccag
ttccatcggatctacatccaccgctacgagaacgtcagtattctttttgcagatgttaaa
ggatttaccaacctctccacaaccttgtccgcccaggagctggtccggatgctcaacgag
ctctttgccagatttgatcgactggcccatgagcatcattgccttcgcattaaaatcctg
ggggactgttactactgtgtttcagggcttcctgagccccgccaggaccacgcccactgc
tgcgttgaaatgggcctcagcatgatcaaaactatcaggtatgtgaggtcaaggacgaag
catgatgtggacatgcggattggaatccactcgggctcagtgctgtgtggggtgttgggc
ctgcggaagtggcagtttgatgtctggtcctgggatgtggacattgcaaacaaactcgaa
tctggaggaatccctgggaggattcacatttccaaagccacactggactgcctcaacggt
gactataacgtagaagagggtcatggtaaagagagaaacgaattcttgaggaagcataat
atagagacctatttgattaagcagcctgaggagagtctgctgtcgttgcctgaagacatt
gtcaaggaatccgtgagctcctcagacgggagaaacagtggggcgacattcacagaagga
tcctggagccctgaactgccctttgataacatagtggggaaacagaacactctggctgcc
ctaacaagaaattcaataaatctacttccaaaccatcttgcacaagctttgcatgtccag
tctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggcgat
aaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctggag
cacaagtattctcaaatgagggatgaagtattcaagtcaaacttggtctgtgcatttatc
gttcttctatttatcacggcgatacaaagtttgcttccttcttcaagggtgatgccaatg
gccatccagttttccatcctgattatgctgcactcggctctggtcctcatcaccacagca
gaggattataagtgtttgcccctcgtcctccggaaaacttgctgttggattaacgagacc
tatttggcccggaacgtcatcatctttgcatccatcttgattaacttcctgggcgccatc
ttgaatatcctgtggtgtgattttgacaagtcaatacccttgaagaacctgactttcaat
tcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcaccggggtg
ctggccatggtgacctgtgcagttttcctccgcctgaactctgtcttgaagctggcggtg
ctgctgattatgatcgccatctacgccctgctgaccgagaccatctatgcgggcctcttt
ctgcgctacgacaacctgaaccacagtggagaagatttcctggggacaaaggaggcatca
ctgctgctgatggccatgttcctccttgctgtgttctaccatggacagcagctggagtac
acagcccgccttgacttcctttggcgagtacaagccaaagaggagatcaatgagatgaag
gagctgagggaacacaacgagaacatgctccggaacattctacccagccacgtggcccgc
cacttcctggagaaagaccgagacaatgaggagctgtactctcaatcctatgatgccgtc
ggagtgatgttcgcctccatcccggggtttgcagacttttactcgcagactgaaatgaat
aaccaaggagtggaatgcctgcgcctgctgaatgagatcattgctgacttcgatgagctg
cttggcgaagaccggttccaggacattgaaaagattaagaccattggcagcacctacatg
gccgtgtcaggcctgtcccccgaaaaacagcaatgtgaagacaagtggggacatttgtgc
gccctggccgacttctccctcgccctgaccgagagcatacaggagatcaacaagcattcc
ttcaacaatttcgaactccggattggcatcagccacggctcggtggtagctggcgttatc
ggcgctaagaaaccacagtatgacatttggggcaaaaccgtgaacctggcaagtcgaatg
gacagcacaggggtcagcggcaggatccaagtccctgaggagacctatctcatcctgaag
gaccagggctttgcctttgactaccgaggggagatctatgtgaagggcatcagtgaacag
gaaggaaaaatcaagacgtactttctgctgggaagagtccaacccaacccattcatcctg
cccccgagaagactgcccgggcagtactccttggccgcggtcgtcctgggccttgtccag
tccctcaacaggcaaaggcagaagcagctcctcaacgagaacaacaacacggggattatc
aagggtcattacaaccggcggactttgttgacacccagcgggccagagcctggagcccaa
gctgaaggcaccgacaagtccgatttgccataa
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