Neomonachus schauinslandi (Hawaiian monk seal): 110579401
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Entry
110579401 CDS
T08474
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04120
Ubiquitin mediated proteolysis
nsu04144
Endocytosis
nsu04330
Notch signaling pathway
nsu04668
TNF signaling pathway
nsu04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
110579401 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
110579401 (ITCH)
04668 TNF signaling pathway
110579401 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110579401 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110579401 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nsu04131
]
110579401 (ITCH)
04121 Ubiquitin system [BR:
nsu04121
]
110579401 (ITCH)
Enzymes [BR:
nsu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
110579401 (ITCH)
Membrane trafficking [BR:
nsu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
110579401 (ITCH)
Ubiquitin system [BR:
nsu04121
]
Ubiquitin ligases (E3)
HECT type E3
110579401 (ITCH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
110579401
NCBI-ProteinID:
XP_021544704
UniProt:
A0A2Y9H5Z8
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Position
10:114050059..114171497
Genome browser
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVMTL
QLVGDKEPTETIGDLSVCLDGLQLESEVVTNGETTGSESASQNDDGSRPKDETRTNTNGS
DEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNSVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcgaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagtagacggacagtcaaagaagacagaaaagtgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttatgacttta
cagcttgtaggtgacaaagagccaacagagacaataggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaactacaggttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagaacaaacacaaatggatca
gatgagcctgaggatgcaggggctggtgaaaataggaaggtcaatgggaataattctcca
tcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaaggagca
acatctggattaataattcctctgactatatctggaggctcaggccctaggccattaaat
tctgtacctcaggctcccctaccacctggttgggagcagagagtggaccagcatggacga
gtttactatgtagatcatattgaaaaaagaacaacctgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttactatgttgaccatttcaca
agaacaacaacgtggcagaggccaacgttggaatctgtccggaactatgaacagtggcag
ctccaacgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatttatggg
aatcaagatttgtttactacatcacaaaataaagaatttgatccccttggtcccctgcca
cctggatgggagaagagaacagacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaagtcaaggccaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagttgatggaattccgtattttgtggaccacaataga
agaacaaccacctatattgatccccgcactggaaaatctgccctagacaatggaccacag
atagcctatgtacgggacttcaaggcaaaagttcagtatttccgattctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaagacattatttgaagattcc
tttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttcttttgtca
cacgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagattaatcctgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgccatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatattgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cctaatggtggaaatattcttgtgacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gaaaagagaatgagacttctgcagtttgttactggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatggaccacaaaaattctgcattgaaaaagttggaaaa
gaaaattggttacccagaagtcatacatgttttaaccgcctggacctgccaccgtacaag
agctatgagcaactgaaagaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtaa
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