Neomonachus schauinslandi (Hawaiian monk seal): 110580209
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Entry
110580209 CDS
T08474
Symbol
PSEN2
Name
(RefSeq) presenilin-2 isoform X2
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04330
Notch signaling pathway
nsu04722
Neurotrophin signaling pathway
nsu05010
Alzheimer disease
nsu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
110580209 (PSEN2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
110580209 (PSEN2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
110580209 (PSEN2)
05022 Pathways of neurodegeneration - multiple diseases
110580209 (PSEN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
nsu01002
]
110580209 (PSEN2)
Peptidases and inhibitors [BR:
nsu01002
]
Aspartic peptidases
Family A22: presenilin family
110580209 (PSEN2)
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Motif
Pfam:
Presenilin
Motif
Other DBs
NCBI-GeneID:
110580209
NCBI-ProteinID:
XP_021545541
UniProt:
A0A2Y9H1T4
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Position
6:complement(65818541..65843466)
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AA seq
448 aa
AA seq
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MLTFMASDSEEEVCDERTSLMSAESPPPRCCQEARQGLEDGENAAQWRSQDSEEDLEEDA
DRYVCSGVPGQPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKSGQLI
YTPFTEDTPSVGQRLLNSVLNTLIMISVIVAMTIFLVMLYKYRCYKFIHGWLIMSSLMLL
FLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMA
LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPGSPGGELEEEEERGV
KLGLGDFIFYSVLVGKAAATSSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISI
TFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgctcacgttcatggcctctgacagtgaggaagaagtgtgtgacgagaggacgtccctg
atgtcggctgagagcccaccgccgcgctgctgccaggaggcccggcagggcctggaggat
ggagagaatgctgcccagtggagaagccaggatagtgaggaggacctcgaagaggacgcg
gaccgctacgtgtgcagtggggtccctgggcagccgtcgggcctggaggaggagctgacc
ctcaaatacggggcgaagcatgtgatcatgctgtttgtgcctgtcacgctgtgcatgatt
gtggtggtggccaccatcaagtccgtgcgcttctacacggagaagagtggccagctcatc
tacacaccattcactgaggacacgccctccgtgggccagcgcctgctcaactctgtgctc
aacaccctcatcatgatcagcgtcatcgtggccatgaccatcttcctggtcatgctctac
aagtaccgctgctacaagttcatccacggctggttgatcatgtcctccctgatgctgcta
tttctcttcacctatatctacctcggggaagtgctcaagacctataatgtggccatggac
taccccaccctgttcctgaccgtctggaacttcggggcagtgggcatggtgtgcatccat
tggaaaggccccttggtgctgcagcaggcctacctcatcatgatcagtgcgctcatggcc
ttggtattcatcaagtacctcccggagtggtccgcgtgggtcattctgggtgccatctct
gtctacgatctcgtggctgtgctgtgccccaaagggccactgaggatgctggtggagact
gcccaggagagaaacgagcccatatttcccgccctgatatactcctctgccatggtgtgg
acggtgggcatggccaagctggacccctcctcccagggagcccttcaactgccctatgac
cccgagatggaagaagactcctatgacagttttggggagccctcatacccagaagtcttt
gagccccccctgcctggttccccaggcggggagctggaggaagaggaggaaaggggcgtg
aagcttggcctgggggactttatcttctacagtgtgctggtgggcaaggcggcagccact
agcagcggggactggaacaccactctggcatgcttcgtggccatcctcattggtttgtgt
ctgaccctcctgctgcttgctgtgttcaagaaggcgctgcccgctctccccatctccatc
acgtttgggctcatcttctacttctccacggacaacctggtgcgtccgttcatggacacc
ttggcctctcatcagctctacatctga
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