Neomonachus schauinslandi (Hawaiian monk seal): 110585808
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Entry
110585808 CDS
T08474
Symbol
IRS2
Name
(RefSeq) LOW QUALITY PROTEIN: insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04022
cGMP-PKG signaling pathway
nsu04068
FoxO signaling pathway
nsu04081
Hormone signaling
nsu04140
Autophagy - animal
nsu04152
AMPK signaling pathway
nsu04211
Longevity regulating pathway
nsu04213
Longevity regulating pathway - multiple species
nsu04910
Insulin signaling pathway
nsu04920
Adipocytokine signaling pathway
nsu04923
Regulation of lipolysis in adipocytes
nsu04930
Type II diabetes mellitus
nsu04931
Insulin resistance
nsu04932
Non-alcoholic fatty liver disease
nsu04935
Growth hormone synthesis, secretion and action
nsu05010
Alzheimer disease
nsu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
110585808 (IRS2)
04022 cGMP-PKG signaling pathway
110585808 (IRS2)
04152 AMPK signaling pathway
110585808 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
110585808 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110585808 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
110585808 (IRS2)
04923 Regulation of lipolysis in adipocytes
110585808 (IRS2)
04920 Adipocytokine signaling pathway
110585808 (IRS2)
04935 Growth hormone synthesis, secretion and action
110585808 (IRS2)
09149 Aging
04211 Longevity regulating pathway
110585808 (IRS2)
04213 Longevity regulating pathway - multiple species
110585808 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
110585808 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
110585808 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110585808 (IRS2)
04932 Non-alcoholic fatty liver disease
110585808 (IRS2)
04931 Insulin resistance
110585808 (IRS2)
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Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
110585808
NCBI-ProteinID:
XP_021551623
UniProt:
A0A2Y9HIL4
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Position
3:3242083..3275686
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AA seq
1331 aa
AA seq
DB search
MASPPLHGPPGPAGGDGPNLNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGDEATATA
GGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYF
AVAAENEQEQEGWYRALTDLVSEGRAGDAPPAAATAASCSASLPGALGGSAGAAAADDSY
GLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMN
IRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRS
KSQSSGSSSTHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTA
SEGDGGAAAGAGAGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGARASKVALAPAG
GALQHSRSMSMPVAHSPPAATSPSSLSSSSGHGSGSYPPPPGPHPHLQHPLHQPASQRPS
SGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGELYGYM
TMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRA
TFSGSSGRLCPSCPVSSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGVALL
GGGSGSCKSDDYMPMSPTSVSAPKQILQPRAAAAALPPAGAAVPAPTPTASRAFPANGGG
YKTSSPAESSPEDSGYMRMWCGSKLSVENADAKLLPNGDYLNMSPSDAGTSGTPPDFFSA
ALHGSGEMLRGVPGYCYSSLPRSYKAPYTCNGDNDQYVLMSSPVGRILEEERLEPPAGPG
SAPSTGALAAAGGHTQPPHPVVPSPSRPSGSLGGRPDGFLNQRCRLVRPTRLSLEGLQTL
PSMHEYPLPPEPKSPGEYINIDFGEAAARLSPPAPPLLASAASSSSLLSASSPASSLGSG
TPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGPQSGDPVGSLDALLSPEASSPYPPLPPRP
PAPTSSLQPQPPPPPPPGELYRLPQASTSQGPSAACSSSPETGDNGDYTEMAFGVAATPP
QPIAAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQASQPPDPHRGAKVIRADPQGGR
RRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVCLRKSSEGGGSGVLGGADERPTSP
RQLQPPPPQQARPRVPSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDEPGLSP
TPQQHPHLQPGDKSAWGRTRSLGGLISAVGXGSSGGGVCGGPGPGALPSANSYASIDFLS
HHLKEATIVKE
NT seq
3996 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcatgggccccccgggccggcgggcggcgacggccccaacctc
aacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcagaag
cacggccacaagcgcttcttcgtgctgcgcgggcccggcgacgaggcgacggcgacagcg
ggtggggggccggcgccgcagccgccgcggctcgagtactacgagagcgagaagaagtgg
cggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaacatcaac
aagcgcgccgacgccaagcacaagtacctgatcgcgctctacaccaaggacgagtacttc
gcggtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcaccgacctg
gtcagcgagggccgcgccggcgacgcgccccccgccgccgccaccgccgcgtcctgcagc
gcctccctgcccggcgccctgggcggctcggccggcgccgccgcggccgatgacagctac
gggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtgaacctgaagccc
aagggcctgggccagagcaagaacctgacgggcgtgtaccgcctgtgcctgtcggcgcgc
accatcggcttcgtgaagctcaactgtgagcagccgtcggtgacgctgcagctcatgaac
atccgccgctgcggccactcggacagcttcttcttcattgaggtgggccggtcggccgtc
acgggcccaggtgagctgtggatgcaggccgacgactcggtggtggcgcagaacatccac
gagaccatcctggaggccatgaaggctctcaaggagctcttcgagttccggccgcgcagt
aagagccagtcgtcgggctcgtcctccacacaccccatcagcgtccctggcgcgcgccgc
caccaccacctggtcaacctgccccccagccagacgggcctggtgcgccgctcgcgcacc
gacagcctggccgccactccgccggccgcgaagtgcagctcctgtcgggtgcgcacggcc
agcgagggcgacggcggcgcggcggcgggggcgggggcgggggcggcgggcggcaggccg
gtgtcagtggccgggagtcccctgagccccgggccggtgcgcgcgcccctgagccgctca
cacaccctgagcggcggctgcggcgcccgtgcgagcaaggtggcgctggcgccggcaggg
ggcgccctgcaacacagccgctccatgtccatgccggtggcgcactcgcccccggccgcc
accagccccagcagcctgtcgtccagcagcgggcacggctccggctcctacccgccgcct
ccaggcccgcatccgcacctgcagcaccccctgcaccagcccgcgagccagcggccctcc
agcggcagcgcctcggcctcgggctcccccagcgatcctggcttcatgtctctggatgag
tacggctccagccctggggacctgagagccttctgcagccaccggagcaacacgcccgag
tccatcgctgagacacccccggccagggacggcagcgggggcgagctgtacgggtacatg
actatggacaggcccctgagccactgtggccgcccctaccgcagggtctcgggggatgga
gcccaggacttggaccgagggctgaggaagaggacttactccctgaccacacctgcccgg
cagcggccggtgccccagccctcctctgcgtccctggatgaatacaccctgatgcgggcc
accttctctggcagctccggccgcctctgcccgtcttgtcccgtgtcgtctcccaaagtg
gcctaccacccctatcccgaggactacggcgacatcgagatcgggtcccataggagctct
agcagtaacctgggtgccgacgatggctacatgcccatgacccctggcgtggctctcctg
ggtggtggcagcggcagctgtaagagtgatgactacatgcccatgagccccactagcgtg
tccgccccgaagcagatcctgcagcctcgcgccgccgccgcggccctgccccccgcggga
gccgcagtgccggcgcccacccctacggccagcagggcctttccagccaacgggggcggc
tacaagacgagctccccagccgagagctcccccgaggacagtgggtacatgcgcatgtgg
tgtggctccaagctgtccgtggagaatgccgacgccaagctgctacccaacggggactac
ctcaacatgtcccccagcgacgcgggtacctcggggacccctcccgacttcttctcggct
gccttgcatggcagcggggagatgctcaggggagtccctggctattgctatagctccctg
ccccgctcctacaaggctccctacacgtgcaacggggacaacgaccagtacgtgctcatg
agctcccccgtggggcgcatcctggaggaagagaggctggaaccgccggccggcccgggg
agcgcgccgtccacaggcgctctcgcggcggcgggcggccacacccagcctcctcaccca
gtagtgccttcgcccagcaggccgagtggcagccttggtggccgccccgacggcttcctg
aaccagcgctgccggttagtgcggcccacacgcctgtccctggaggggcttcagaccctg
cccagcatgcacgagtatcctctgccgcccgagcccaagagccccggcgagtacatcaac
attgacttcggcgaggccgcggctcgcctgtctccgcccgcgcctccgctgctggcttcg
gcggcctcctcgtcctcgctgctgtcggccagcagcccggcctcatccctaggctcgggc
accccaggcacgagcagcgacagcaggcagcgctccccactctccgactacatgaacctc
gacttcagctcgcccaagtcacccaagccgggcccccagagcggggaccccgtgggctcc
ctggatgccctcctgtcccccgaggcctcgtccccctacccgccgctgcccccgcgccct
cccgcccccacctcctccctgcagccgcagcctcctccgccgcccccgccaggggagctg
taccgcctgccccaggcgtccacttcccagggccccagcgctgcctgctcttcgtccccg
gagactggggacaatggggactacaccgagatggcctttggcgtagctgccaccccgcca
caacccatcgcggcccccccgaagccggaaggtgcccgcgtgaccagccccacgtccggc
ctgaagaggctgagtctcatggatcaggtgtcgggagtggaggccttcctgcaggcgagc
cagcccccagacccgcaccggggagccaaggtcatccgcgcagacccacaggggggccgc
cgccgccacagctccgagaccttctcctcgaccaccactgtgactcccgtgtccccctcc
ttcgcccataaccctaagcgccacaactcggcctctgtggaaaacgtctgtctcaggaaa
agcagcgaagggggcggcagcggcgtcctgggtggggcagacgagcgccccacctccccc
cgccagttgcagccaccgcccccccagcaggcgcgcccaagggtgccgagtcagcctggg
ggcttggttggctgcccggggggcagtggctctccaatgcgcagggagacctctgccggc
ttccagaacggcctcaattacatcgccatcgacgtgagggacgagcctgggctgtcgccc
accccgcagcagcatccgcatctacagcccggagacaagagcgcctggggccgcacccgc
agcctcgggggtctcatcagcgctgtggggnngggcagcagcggcggtggggtgtgtggg
gggccgggccctggcgccctcccctccgccaacagctatgccagcattgacttcttgtcc
catcacctgaaggaggccaccattgtgaaagagtga
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