Neomonachus schauinslandi (Hawaiian monk seal): 110587399
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Entry
110587399 CDS
T08474
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04022
cGMP-PKG signaling pathway
nsu04024
cAMP signaling pathway
nsu04062
Chemokine signaling pathway
nsu04071
Sphingolipid signaling pathway
nsu04270
Vascular smooth muscle contraction
nsu04310
Wnt signaling pathway
nsu04360
Axon guidance
nsu04510
Focal adhesion
nsu04519
Cadherin signaling
nsu04520
Adherens junction
nsu04530
Tight junction
nsu04611
Platelet activation
nsu04670
Leukocyte transendothelial migration
nsu04810
Regulation of actin cytoskeleton
nsu04921
Oxytocin signaling pathway
nsu05132
Salmonella infection
nsu05135
Yersinia infection
nsu05163
Human cytomegalovirus infection
nsu05200
Pathways in cancer
nsu05205
Proteoglycans in cancer
nsu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
110587399 (ROCK2)
04071 Sphingolipid signaling pathway
110587399 (ROCK2)
04024 cAMP signaling pathway
110587399 (ROCK2)
04022 cGMP-PKG signaling pathway
110587399 (ROCK2)
09133 Signaling molecules and interaction
04519 Cadherin signaling
110587399 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110587399 (ROCK2)
04520 Adherens junction
110587399 (ROCK2)
04530 Tight junction
110587399 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110587399 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110587399 (ROCK2)
04670 Leukocyte transendothelial migration
110587399 (ROCK2)
04062 Chemokine signaling pathway
110587399 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
110587399 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
110587399 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
110587399 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110587399 (ROCK2)
05205 Proteoglycans in cancer
110587399 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
110587399 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
110587399 (ROCK2)
05135 Yersinia infection
110587399 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110587399 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110587399 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
nsu03036
]
110587399 (ROCK2)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
110587399 (ROCK2)
Protein kinases [BR:
nsu01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
110587399 (ROCK2)
Chromosome and associated proteins [BR:
nsu03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
110587399 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
APH
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
110587399
NCBI-ProteinID:
XP_044774805
UniProt:
A0A8M1MNS4
LinkDB
All DBs
Position
10:complement(8153753..8293168)
Genome browser
AA seq
1388 aa
AA seq
DB search
MSRPPATGKMPGAPEAVPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFP
ALRKNKNIDNFLNRYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAM
KLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMD
ETGMVHCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLV
GTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWN
WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENL
LLSDSSSCRENDSLQSRKNEESQEIQKKLYTLEEHLSTEIQAKEELEQKCKSVNTRFEKV
AKELEEEITLRKNVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNR
DLQDKNCLLETAKLKLEKEFINLQSVLESERRDRTHGSEIINDLQGRISGLEEDLKNGKI
LLAKAEMEKRQLQERLTDLEKEKNNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEMEKKLSEERTLKQKVENLLLEAEKRCSIFDCDLKQSQQKINELLK
QKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMS
LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKELQQK
KQDLQEERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQE
LTEKDATIASLEETNRTLTSDVANLANEKEELNNKWKDAQEQLSRLKDEEISAAAIKAQF
EKQLLTERTLKTQAVNKLAEIMNRKEPVKRGSDTDVRRKEKENRKLHMELKSEREKLTQQ
MIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPG
DAEADDGFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVL
DIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKG
HEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYD
ISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSR
QLAPNKPS
NT seq
4167 nt
NT seq
+upstream
nt +downstream
nt
atgagccggcccccggcgacggggaaaatgcccggcgcccccgaggccgtgccgggggac
ggggcgggcgcgagccgccagaggaagctggaggcgctgatccgagaccctcgctcaccc
atcaacgtggagagcttgttggatggcttaaattccttggtccttgatttggattttcct
gctttgagaaaaaacaagaatatagataattttttaaatagatatgagaaaattgtgaaa
aaaatcagaggtctacagatgaaggcagaagactatgatgttgttaaagttattggaaga
ggtgcttttggtgaagtgcagctggttcgtcataaggcatcacagaaggtttatgctatg
aagcttcttagtaagtttgaaatgataaaaagatctgattctgcatttttctgggaagag
agagatattatggcctttgccaacagtccctgggtggttcagctcttttgtgcttttcaa
gatgataagtatctgtacatggtaatggagtacatgcctggtggagatcttgtaaacctt
atgagtaactatgatgtacctgaaaaatgggccaaattttatactgctgaagttgttctt
gctctggatgccatacactccatgggcttaattcacagagatgtaaaacctgacaacatg
ctcttggataaacatggacatctaaagttggcagattttggcacatgtatgaagatggat
gaaacaggcatggtgcattgtgatacggcagttggaacacctgattatatttcacctgag
gttctcaaatcacaagggggtgatggttactatgggcgagaatgtgattggtggtctgtg
ggtgttttcctttttgagatgctggtgggggatactccattttatgcagattcacttgta
ggaacatatagcaaaattatggatcataaaaactcactctgtttccctgaagatgcagaa
atttctaaacatgcgaagaatctcatttgtgccttcttaacagatagggaggtacgactt
gggagaaatggggtagaagaaatcaaacagcatcctttctttaagaatgatcagtggaat
tgggataacataagagagacggcggctcctgtagtacctgagctcagcagtgacatagac
agcagcaattttgatgacatcgaagatgataaaggagatgtagaaaccttcccgattcct
aaagcttttgtgggaaatcagctaccttttataggatttacctactatagagaaaatttg
ttattaagtgactcttcatcttgtagagaaaatgattcattacaatcaaggaagaatgaa
gaaagccaagagattcagaaaaaattatacacattagaagaacaccttagcactgaaata
caagccaaagaggaactagagcaaaagtgcaaatctgttaatactcgctttgagaaagta
gcaaaggaactagaagaagagattactttaaggaaaaatgtggaatcagcattaagacaa
ttagaaagagaaaaggcacttcttcaacacaaaaatgcagagtatcagcggaaagctgat
cacgaagcagacaagaagcgaaatttggaaaatgatgttaacagtttaaaggatcaactt
gaagatttgaaaaaaagaaatcagaactctcaaatatccactgagaaagtgaatcagctc
cagagacaactggatgaaaccaatgctttgctgagaacagaatctgatactgcggcccgg
ttaagaaaaacccaggcagaaagttcaaaacagattcagcagctggaatctaacaataga
gatcttcaagataaaaattgcctgctggagactgctaagttaaaacttgaaaaggaattt
atcaatcttcagtcagttctagaatctgaaaggagggaccgaactcatggatccgagata
attaatgacttacaaggtagaatatctggcctagaagaagatttaaagaatggcaaaatc
ttattagcaaaagcagagatggagaagagacaactacaggagagacttactgatttggaa
aaggaaaagaacaacatggaaatagatatgacataccaactaaaagttatacagcagagc
ttagaacaagaagaagctgagcataaggctacaaaagcacggctggcagataaaaataag
atttatgaatccattgaagaagcaaaatcagaagccatgaaagaaatggagaaaaagctc
tcagaggaaaggacgttaaagcagaaagtggagaacctattgctggaagctgagaagaga
tgctctatatttgactgtgacctcaaacagtcacagcagaaaatcaatgaactccttaaa
cagaaagatgtgctaaatgaggatgttagaaatttgacattaaaaatagagcaggaaact
cagaagcgctgccttacacaaaatgacttgaagatgcaaacacagcaagttaacacatta
aaaatgtcagaaaagcagttaaaacaagagaataatcatctcatggaaatgaaaatgagc
ttggaaaagcagaatgctgaacttcgaaaagaacgtcaagatgcagatgggcaaatgaaa
gaacttcaggatcagcttgaagcggagcagtatttctcaaccctctataaaacacaggtg
agggaacttaaagaagaatgtgaagaaaagaccaaactttgtaaagagttacaacagaag
aaacaggacttacaggaagaaagggactccttggctgctcaactggagatcaccttgacc
aaagcagattcagagcagctggctcgttcaattgctgaagagcaatattctgatttggag
aaagagaaaatcatgaaggagcttgagatcaaagagatgatggctagacacaaacaggag
ctcactgaaaaagatgctacaattgcatctcttgaagaaacgaataggacactaactagt
gatgttgccaatcttgcaaatgagaaagaagaattaaataacaaatggaaagatgcccaa
gaacagctgtcacggctgaaagatgaggagatcagcgcagccgctattaaagcacagttt
gagaagcagctgctcacagagagaacacttaaaactcaagctgtgaataagttggctgag
ataatgaatcgaaaagaacctgtcaagcgtggtagtgacactgatgtgcggagaaaagag
aaagagaatagaaagctacatatggagcttaaatctgaacgtgaaaaattgacccagcag
atgatcaagtatcagaaagaactgaatgaaatgcaggctcaaatagctgaagagagccag
attcgaattgaactgcagatgacactggacagtaaagatagtgacattgagcagctgcgg
tcacagctccaggcgttgcatatcggtctggatagttccagtataggcagtggaccaggg
gatgctgaggcagatgatggatttcccgaatcaagactagaaggatggctttcattgcct
gtacgaaacaacactaagaagtttggatgggttaaaaagtatgtgattgtaagcagtaag
aagattcttttctatgacagtgaacaagataaagaacaatctaatccttacatggtttta
gatatagacaaattatttcatgtccgaccagttacacagacagatgtatacagagcagat
gctaaagaaattccaaggatatttcagattctgtatgccaatgaaggagagagtaagaag
gaacaagaatttccagtggagccagtgggagaaaaatcaaattatatttgccataaggga
cacgaatttattcctaccctctatcatttcccaaccaactgtgaggcttgtatgaagcca
ctgtggcatatgtttaaacctcctcctgctttagagtgccggcgctgccatattaaatgt
cataaagatcacatggacaaaaaggaggagattatagcaccttgcaaagtttactatgat
atttcgacggcaaagaatcttttgttgttagcaaattctacagaagaacagcagaagtgg
gttagtcggttggtgaaaaagatccctaaaaagcctccagctccagacccttttgcacgg
tcatctcctagaacctcgatgaagatacaacaaaaccagtctattagacggccaagtcga
cagcttgccccaaacaaaccaagctag
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