Neomonachus schauinslandi (Hawaiian monk seal): 110588874
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Entry
110588874 CDS
T08474
Symbol
HK2
Name
(RefSeq) hexokinase-2
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00010
Glycolysis / Gluconeogenesis
nsu00051
Fructose and mannose metabolism
nsu00052
Galactose metabolism
nsu00500
Starch and sucrose metabolism
nsu00520
Amino sugar and nucleotide sugar metabolism
nsu00524
Neomycin, kanamycin and gentamicin biosynthesis
nsu01100
Metabolic pathways
nsu01200
Carbon metabolism
nsu01250
Biosynthesis of nucleotide sugars
nsu04066
HIF-1 signaling pathway
nsu04910
Insulin signaling pathway
nsu04930
Type II diabetes mellitus
nsu04973
Carbohydrate digestion and absorption
nsu05230
Central carbon metabolism in cancer
Module
nsu_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
nsu_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110588874 (HK2)
00051 Fructose and mannose metabolism
110588874 (HK2)
00052 Galactose metabolism
110588874 (HK2)
00500 Starch and sucrose metabolism
110588874 (HK2)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
110588874 (HK2)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
110588874 (HK2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110588874 (HK2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
110588874 (HK2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
110588874 (HK2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110588874 (HK2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110588874 (HK2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nsu04131
]
110588874 (HK2)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
110588874 (HK2)
Membrane trafficking [BR:
nsu04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
110588874 (HK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
110588874
NCBI-ProteinID:
XP_021554932
UniProt:
A0A2Y9HTM5
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All DBs
Position
10:complement(48023109..48086277)
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AA seq
917 aa
AA seq
DB search
MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDENLLEISKRFRKEMEKGLGATTHPTAS
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDLMR
GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCVQTKLDESFLVSWTKGFKSSGV
EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGILDDFRTEFDQEIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFGGKLSPGLLATGQFETKDVSDIEGEKDGTWKAREVLVRLG
IDPTQEDCVATHRICQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH
PHFAKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQNTLESLKLS
REQLLEVKRRMNVEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD
FRTEFDVAVDELSLNPGRQRFEKMISGMYLGEIVRNILIDFTKHGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG
AALITAVACRIREAGQR
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgatcgcctcgcatctgctcgcctatttcttcacggagctcaaccatgaccaagtgcag
aaggttgaccagtatctctaccacatgcgtctttctgatgagaaccttctggagatctct
aagcggttccgcaaggagatggagaaagggcttggagccaccacccaccccactgcttca
gtgaaaatgctgcccacctttgtgaggtctactccggatgggacagaacacggagagttc
ctggctctggacctcggagggacaaacttccgtgtgcttcgggtaagagtaacagacaat
gggctccagaaggtcgagatggagaaccagatctatgccatccccgaggacctcatgaga
ggcagcggcacccagctgtttgaccacattgcagaatgcctggctaacttcatggataag
ctacaaatcaaagacaagaagctccccttgggttttactttctcattcccctgcgtccaa
acaaaactagatgagagtttcctggtctcctggaccaaggggttcaagtccagtggtgtg
gaagggaaagacgtggttactctgatccggaaggccatccagaggagaggggactttgat
attgatatcgtggccgtggtgaacgacacagttgggaccatgatgacctgtggttatgat
gaccagaattgcgagattggtctcattgtaggcacgggcagcaacgcctgctacatggaa
gagatgcgccacattgacatggtggagggcgacgaggggcggatgtgtatcaacatggag
tggggggccttcggggatgatggcatactcgatgacttccgcactgagtttgatcaggag
atcgacatgggctccctgaaccccgggaaacaactattcgagaagatgatcagtgggatg
tacatgggagaactggtgaggcttatcctggtgaagatggccaaggaagagctgcttttc
ggggggaagctcagcccagggctccttgccactggccagtttgagaccaaagatgtttca
gatatcgaaggggagaaggacggcacctggaaggcccgtgaggtgctggtgcggctgggc
atagacccgacacaggaggactgcgtggccactcaccggatctgccagatcgtgtctacg
cgctcagccagcctgtgtgcggccaccctggcggccgtgctgcggcgcatcaaggagaac
aagggcgaggagcggctgcgctccaccattggggtggacggctctgtctacaagaagcac
ccacactttgccaagcgtcttcacaagacggtgcggcgcctggtgcccgactgtgacgtc
cgcttccttcgttctgaggatggcagtggcaagggggcagccatggtgacggcggtggcc
taccggctggctgaccaacaccgagcccgccagaataccctggagtctctgaagctgagc
cgcgagcagctgctggaggtcaagaggaggatgaacgtagagatggagcgaggtctgagc
aaggagactcacgccattgcccctgtcaagatgctgcccacctacgtgtgtgccacgcct
gatggcacagagaaaggtgacttcctggccttggaccttgggggtaccaatttccgggtc
ctgctggtgcgagtgaggaatggaaagcggcgtggagtagagatgcacaacaagatctac
tctatcccgcaggaggtcatgcacggcacgggggacgagctctttgaccacatcgtccag
tgcatcgccgacttccttgagtacatgggcatgaagggcgtgtccctgcctctgggtttc
accttctccttcccctgccagcagaacagcctggatgagagcatcctcctcaagtggact
aaaggcttcaaggcatcgggctgtgagggagaggatgtggtcacgctgctgaaggaggcc
atccaccggcgagaggagtttgacctggacgtggtcgctgtggtgaatgacacagttggg
actatgatgacctgtggctatgaagaccctcactgcgaagtcggcctcatcgttggcacg
ggcagcaacgcctgctacatggaggagatgcggaacgtggagctggtagagggggaggag
ggccggatgtgtgtcaacatggagtggggggccttcggggacaacggatgcctcgacgac
ttccgcacggaatttgatgtggctgtggatgagctttccctcaaccctggcagacagagg
ttcgagaaaatgatcagtggcatgtacttgggggagattgtccgtaacatcctcatcgat
ttcaccaagcatgggctgctcttccgtggccgcatctcagagcggctcaagacaagggga
atctttgaaaccaagttcctgtctcagattgagagtgactgcctggccctgctgcaggtc
cgcgccatcctgcaccacctggggctcgagagcacatgtgacgatagcatcattgtcaaa
gaggtgtgcaccgtggtggcgcggcgggcagcccagctctgtggcgcgggcatggccgcc
gtggtggacaagatccgagagaaccgggggctggacaccctcaaagtgaccgtgggcgtg
gatgggaccctctacaagctacaccctcactttgccaaagtcatgcacgagacggtgaag
gacctggctccgaaatgtgacgtgtccttcctggagtcagaggacggcagcgggaagggg
gcggctctcattactgctgtggcctgccgcatccgcgaggctggccagcgatag
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