Neomonachus schauinslandi (Hawaiian monk seal): 110589447
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Entry
110589447 CDS
T08474
Symbol
RET
Name
(RefSeq) LOW QUALITY PROTEIN: proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04010
MAPK signaling pathway
nsu04020
Calcium signaling pathway
nsu04151
PI3K-Akt signaling pathway
nsu05200
Pathways in cancer
nsu05216
Thyroid cancer
nsu05223
Non-small cell lung cancer
nsu05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110589447 (RET)
04020 Calcium signaling pathway
110589447 (RET)
04151 PI3K-Akt signaling pathway
110589447 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110589447 (RET)
05230 Central carbon metabolism in cancer
110589447 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
110589447 (RET)
05223 Non-small cell lung cancer
110589447 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
nsu01001
]
110589447 (RET)
Enzymes [BR:
nsu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110589447 (RET)
Protein kinases [BR:
nsu01001
]
Receptor tyrosine kinases (RTK)
RET family
110589447 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
110589447
NCBI-ProteinID:
XP_021555647
UniProt:
A0A2Y9HVS1
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Position
6:complement(117375119..117425104)
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AA seq
1131 aa
AA seq
DB search
MAKATATAGAAGLRLLLLLPLLSEASQIMSDWRVPFCQAPLGLYFSRDVYWEKLYVDQPA
GMPLLYVHALRDVPEEVPSFRLGQHLYGIAYRARLHENDWIRIEEDTGLLYLNRSLDRST
WEKLSIQNGGFPVLTIYLQVFLLSASLREGECQWPGCARVYFSFINTSFPACGSLKPREL
CFPETSVSFRIRENRPPGTFHQFRLLPVQFLCPNISVSYRLLEGENLPFRCAPDSLEVST
RWALDRELREKYELVAACMVRVGARKEEVVMVPFPVTVYDEDDSAPTFLGGFDTASAVVE
FKRKEGTVVATIRVFDADVVPASGELLRRYTSTLLPGDAWALQTFRVEHSPNETLTQANG
SFVRATVHDYRLVLNRSLPISECRSLQLAVLVNDSDFQGPGEGVLRLHFNVSVLPVSLHL
PSAYSFTVSRRAHRFAQIGKVCVDNCQEFSGIHVQYKLQLSSTNCSVLGVVTSAEDTMGT
LFVNDTEALQRLDCSQLQYTVVATNRPTRRQTQAPLVVTVEGTYVAEEPGCPLSCAVSKR
RPECEECGGLGSLTGRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQD
CLRGGSIIGGHEPGDRWGIKAGFGICNCFPEEKKCFCEPEDSQDPLCDELCRTVIAAAVL
FSFIVSMLLSTFCIHRYHKNAHKPPVASAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQ
VSVDAFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKEN
ASPSELRDLLSEFNLLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAG
PGYVGSGGSRSSSYLDNPEERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVA
EGRKMKISDFGLSRDVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWE
IVTLGGNPYPGIPPERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISK
DLEKMMVKNRDYLDLAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYG
MSDPNWPEESPVPLTRADGTNTVCPRYANDSVYANWMVSPSAAQLTDAFDS
NT seq
3396 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggcgacggccggcgccgcggggctgcggttgctgctgctgctgccg
ctgctcagcgaagcctctcagatcatgagtgattggcgcgtgcccttctgccaggctccg
ctaggactctacttctctagggatgtttactgggagaaactgtatgtggaccagccagct
ggcatgcccctgctctacgtccacgccctgcgggacgtccccgaggaggtgcccagcttc
cgcctgggtcagcatctctacggcatcgcctaccgtgcgaggctgcatgagaatgactgg
atccgcatcgaggaggacacaggccttctctaccttaaccggagcctagatcgcagcacc
tgggagaagctcagcatccaaaatggcggcttccctgtgctcaccatctacctccaggtc
ttcctgttgtctgcgtccctgcgtgagggcgagtgccagtggccaggctgtgcccgggtg
tacttctccttcatcaacacttccttcccggcttgtggttccctcaaaccccgggagctc
tgctttcccgaaacaagcgtctccttccgcatcagagagaacaggcctcctggcaccttc
caccaattccggctgctgcctgtgcagttcctgtgccccaacatcagtgtgtcctacagg
ctcctagaaggtgagaatctgcccttccgttgcgccccggacagcctggaggtgagcaca
cgctgggccctggaccgcgagctgcgggagaagtatgagctggtggccgcgtgcatggtg
cgcgtcggcgcgcgcaaagaggaggtggtgatggtgcccttccccgtgaccgtgtacgat
gaggacgactcggcgcccaccttcctcgggggcttcgacaccgccagcgctgtggtggag
ttcaagaggaaggagggcactgtggtggccacgatacgtgtcttcgacgcagatgtggtg
ccagcatctggggagctgctgaggcgatacacaagcacactactccctggggatgcctgg
gccctccagactttccgtgtcgagcactcacccaacgagaccttgacccaggccaacggc
agctttgtgcgggcaactgtgcatgactacaggctggttctcaaccggagcctccccatc
tcggagtgccgctcgctgcagctggccgtgctggtcaatgactcggacttccagggcccg
ggggagggcgtcctccgcctccacttcaacgtgagcgtgctgcccgtcagcctgcactta
cccagcgcctactccttcactgtgagcaggcgagcccaccgcttcgcccagattgggaaa
gtctgtgtggacaactgccaggagttcagcggcatccacgtgcagtacaagctgcagctg
tccagcaccaactgcagtgtcctgggggtggtcacctcagccgaggacaccatggggacc
ctgttcgtgaatgacacggaagccctgcagcggctcgattgttctcaactccagtacacg
gtggtggccaccaaccggccaacccgcaggcagacccaggccccgctggtcgtcaccgtg
gaggggacgtatgtggctgaggagccaggctgccccctgtcctgtgcagtcagcaagagg
cggcctgagtgtgaggagtgcggcggcctgggctctctgacgggcaggtgcgagtggaga
cagggagatggcaaagggatcaccaggaacttctccacctgctcccccagcatcaagacc
tgccccgatggccactgtgatgctgtggagagcagaaatgtcaacatctgcccccaggac
tgcctccggggcggcagcatcattggtgggcacgagccaggggaccgctgggggataaaa
gctggcttcggtatctgcaactgtttccctgaagagaagaagtgcttctgtgagcctgaa
gacagccaggacccgctgtgtgatgagctctgccgcacagtgatcgcggcggccgtgctc
ttctccttcatcgtctccatgctgctctccaccttctgcatccaccgctaccacaagaat
gcccacaagccgcctgtcgcctccgccgagatgactttccgccggccggcccaggccttc
ccagtaagctactcctcatcgggcgcccgccggccctccttggactccatggagaaccag
gtttctgtggacgccttcaagatcccggaggatccgaagtgggaattccctcggaagaac
ttggttcttggaaaaactctgggagaaggcgaatttggaaaagtggttaaggcaacagcc
ttccggcttaaaggcaaagcaggatacacgaccgtggccgtgaagatgctgaaagagaac
gcctccccaagcgagctgcgggacctgctgtcagagttcaacctcctgaagcaggtcaac
cacccgcatgtcatcaagctgtatggggcctgcagccaggatgggccactcttcctcatt
gtggagtatgccaagtacggctccctgcggggcttcctccgagagagccgcaaggcgggg
ccgggctacgtgggcagtggaggcagccgcagctccagctacctggacaaccccgaggag
cgggccctgaccatgggcgacctaatctccttcgcctggcagatctctcgggggatgcgg
tacctggcggagatgaagcttgtccatcgggacttggccgccagaaacgtcctggtagcc
gaggggcggaagatgaagatttcggattttggcctatcccgagatgtttatgaagaggat
tcctacgtgaagaggagcaagggtcggattccagtcaaatggatggcaattgagtctctt
ttcgatcatatctacaccacccaaagtgatgtgtggtcgttcggtgtcctgctgtgggag
attgtgactctggggggcaacccctaccccgggattcctccggagcggctcttcaacctt
ctgaagacaggctaccggatggagaggcccgacaactgcagtgaggagatgtacggtcta
atgctgcagtgttggaagcaggaaccagacaagaggccagtgtttgctgacatcagcaaa
gacctggagaagatgatggttaagaacagagactacttggacctggccgcgtccacccca
tctgactccctgctttacgacgacggcctctcggaggaggagacgcccctggtggactgt
aataatgctcccctccctcgagccctcccctccacgtggattgaaaacaaactctatggc
atgtcagacccgaactggcctgaagagagtcctgtaccactcacgagagctgatggcact
aacactgtgtgtccaagatatgcaaatgatagtgtatatgctaactggatggtttcaccc
tcagcggcacaattaacggacgcatttgatagttaa
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