KEGG   Neomonachus schauinslandi (Hawaiian monk seal): 110590084
Entry
110590084         CDS       T08474                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X2
  KO
K13375  transforming growth factor beta-1
Organism
nsu  Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu04010  MAPK signaling pathway
nsu04060  Cytokine-cytokine receptor interaction
nsu04068  FoxO signaling pathway
nsu04110  Cell cycle
nsu04148  Efferocytosis
nsu04218  Cellular senescence
nsu04350  TGF-beta signaling pathway
nsu04380  Osteoclast differentiation
nsu04390  Hippo signaling pathway
nsu04518  Integrin signaling
nsu04659  Th17 cell differentiation
nsu04672  Intestinal immune network for IgA production
nsu04926  Relaxin signaling pathway
nsu04932  Non-alcoholic fatty liver disease
nsu04933  AGE-RAGE signaling pathway in diabetic complications
nsu05140  Leishmaniasis
nsu05142  Chagas disease
nsu05144  Malaria
nsu05145  Toxoplasmosis
nsu05146  Amoebiasis
nsu05152  Tuberculosis
nsu05161  Hepatitis B
nsu05166  Human T-cell leukemia virus 1 infection
nsu05200  Pathways in cancer
nsu05205  Proteoglycans in cancer
nsu05210  Colorectal cancer
nsu05211  Renal cell carcinoma
nsu05212  Pancreatic cancer
nsu05220  Chronic myeloid leukemia
nsu05225  Hepatocellular carcinoma
nsu05226  Gastric cancer
nsu05321  Inflammatory bowel disease
nsu05323  Rheumatoid arthritis
nsu05410  Hypertrophic cardiomyopathy
nsu05414  Dilated cardiomyopathy
nsu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:nsu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110590084 (TGFB1)
   04350 TGF-beta signaling pathway
    110590084 (TGFB1)
   04390 Hippo signaling pathway
    110590084 (TGFB1)
   04068 FoxO signaling pathway
    110590084 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    110590084 (TGFB1)
   04518 Integrin signaling
    110590084 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    110590084 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    110590084 (TGFB1)
   04218 Cellular senescence
    110590084 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    110590084 (TGFB1)
   04672 Intestinal immune network for IgA production
    110590084 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    110590084 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    110590084 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110590084 (TGFB1)
   05205 Proteoglycans in cancer
    110590084 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    110590084 (TGFB1)
   05212 Pancreatic cancer
    110590084 (TGFB1)
   05225 Hepatocellular carcinoma
    110590084 (TGFB1)
   05226 Gastric cancer
    110590084 (TGFB1)
   05220 Chronic myeloid leukemia
    110590084 (TGFB1)
   05211 Renal cell carcinoma
    110590084 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    110590084 (TGFB1)
   05161 Hepatitis B
    110590084 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    110590084 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    110590084 (TGFB1)
   05144 Malaria
    110590084 (TGFB1)
   05145 Toxoplasmosis
    110590084 (TGFB1)
   05140 Leishmaniasis
    110590084 (TGFB1)
   05142 Chagas disease
    110590084 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    110590084 (TGFB1)
   05321 Inflammatory bowel disease
    110590084 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    110590084 (TGFB1)
   05414 Dilated cardiomyopathy
    110590084 (TGFB1)
   05415 Diabetic cardiomyopathy
    110590084 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    110590084 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    110590084 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:nsu03110]
    110590084 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:nsu04052]
    110590084 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:nsu00536]
    110590084 (TGFB1)
Chaperones and folding catalysts [BR:nsu03110]
 Intramolecular chaperones
  Others
   110590084 (TGFB1)
Cytokines and neuropeptides [BR:nsu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   110590084 (TGFB1)
Glycosaminoglycan binding proteins [BR:nsu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   110590084 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 110590084
NCBI-ProteinID: XP_021556461
UniProt: A0A2Y9HY24
LinkDB
Position
16:12077101..12090091
AA seq 390 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVENSNKI
YEKIKKSPHSIYMLFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNDSWR
YLSNRLLAPSDTPEWLSFDVTGVVRQWLSHGGEVEGFRLSAHCSCDSKDNTLQVDINGLR
SSRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRQRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctccgggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgacgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggaactg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggggaggtgccgcccggcccgctgcccgaggctgtgctggccctt
tacaacagcacccgcgaccgggtggcgggggagagcgccgagccggagcccgagcctgag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacagcaacaaaatc
tatgagaaaatcaagaaaagcccgcacagcatatatatgctcttcaacacgtcggagctc
cgagaagcagtgcctgagcccgtcttgctctcccgggcagagttgcgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatacagcaacgattcctggcgc
tacctcagcaaccggctgctggcgcccagcgacacgccagaatggctgtccttcgatgtc
actggagttgtgcggcagtggctgagccacggaggggaagtagagggctttcgcctcagt
gcccactgttcgtgtgacagcaaagataacacactgcaagtggacatcaacgggctccgt
tccagccgccgaggtgacctggccaccattcacggcatgaaccggcccttcctgctcctc
atggccaccccactggagagggcccagcaccttcacagctcccggcagcgccgggccctg
gacaccaactactgcttcagctccaccgagaagaactgctgcgtgcggcagctctatatc
gacttccggaaggatctgggctggaagtggatccacgagcccaagggctaccacgccaac
ttctgcctggggccctgcccctacatttggagcctggacacgcagtacagcaaggtcctg
gccctgtacaaccagcacaacccgggcgcgtcggcggcgccgtgctgcgtgcctcaggcg
ctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctgtcc
aacatgatcgtgcgctcctgcaagtgcagctga

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