Neomonachus schauinslandi (Hawaiian monk seal): 110590913
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Entry
110590913 CDS
T08474
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2 isoform X1
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
nsu
Neomonachus schauinslandi (Hawaiian monk seal)
Pathway
nsu00120
Primary bile acid biosynthesis
nsu01040
Biosynthesis of unsaturated fatty acids
nsu01100
Metabolic pathways
nsu01212
Fatty acid metabolism
nsu04146
Peroxisome
Module
nsu_M00861
beta-Oxidation, peroxisome, VLCFA
nsu_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
nsu00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
110590913 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
110590913 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
110590913 (HSD17B4)
Enzymes [BR:
nsu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
110590913 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
110590913 (HSD17B4)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
MaoC_dehydratas
adh_short
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
Epimerase
Motif
Other DBs
NCBI-GeneID:
110590913
NCBI-ProteinID:
XP_021557432
UniProt:
A0A2Y9I0B9
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Position
7:12664070..12751867
Genome browser
AA seq
737 aa
AA seq
DB search
MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDIKGLSKGSLAAADKVV
EEIRSKGGKAVANYDSVEAGEKVVRTALEAFGRIDVVVNNAGILRDNSFGRISDEDWDII
HRVHLRGSFQVTRAAWDHMKKQKFGRIVMTASASGIYGNFGQANYSAAKLGLLGLSNTLA
IEGQKSNIHCNTIAPAAGSRMTQSIMPEDLVEALKPDYVAPLVLWLCHESCEENGSLFEV
GGGWIGKLRWERALGAVVRQKNQPMTPEAVKANWKKICDFDNASKPQRIQESIGSIIEVL
NKIDSERGVSTNPTSHASSTATSEFAGAIGHKLPPFSSAYTELEAIMYALGVGASIKEPK
DMKFIYEGSTDFSCLPTFGVIIAQKPIVGGELSGIPGFSVNLEKVLHGEQYLELYKPLPR
AGNLKCEAVIADVLDKGSGLVILVDVYSYFEEELVCYNQFSIFVVGSGGIGGKRTSDKVK
VALAVPNRPPDAVLRDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF
SARHVLQQYADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIEETGDVVIS
NAYVDLIPTSDTSAKTPSEGGKLQSTLVFEEIGRRLKDIGHEVAEKVNAVFEWHITKGGH
TAAKWTVDLKSGSGKVYQGPAKGSADATITLSDEDFMDVVLGKLDPQKAFFNGRLKARGN
IMLSQKLQMILKDYAKL
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgcccctgcgtttcgacgggcgggtggtcctggtcaccggcgcggggggagga
ctgggccgagcctatgccctggcttttgcagaaagaggtgcatccgttgttgtgaatgac
ttaggaggggacatcaagggattgagtaaaggctccttagcagctgctgataaggttgtt
gaagaaataagaagtaaaggtggaaaagccgtggccaactatgattcggtggaagcagga
gagaaggttgtgaggacagcactagaagcttttggaagaatagatgttgtggtcaacaat
gccggaattctgagggacaattcttttggtaggataagtgacgaagactgggatataatc
cacagagtccatttgcgaggctcgttccaagttactcgggcagcttgggatcatatgaag
aaacagaagtttggaaggattgttatgactgcatcagcttcaggaatttatggcaacttt
ggccaggccaattatagtgctgcaaagctgggtcttctgggcctttcaaatacccttgca
attgaaggccagaaaagcaacattcactgtaacaccattgcccctgctgctggatcacgg
atgacccaaagcattatgcctgaagatctcgtggaagctctgaagccggattacgtggcc
cccctggtcctttggctttgccatgagagctgtgaggaaaatggtagcttgtttgaggtt
ggaggaggatggattggaaaactacgctgggagcgggcccttggagccgttgtgagacag
aagaatcagccaatgactcctgaggccgtgaaggccaactggaagaagatctgtgacttt
gataatgccagcaagcctcagagaattcaagaatcaattggcagtataattgaagttcta
aataaaatagattcagagagaggagtttcgacaaatcctacgagtcacgcatcatcaaca
gctacatcggaatttgctggagccattggccataagcttcctcccttttcttctgcttac
acggaactggaagctattatgtatgctcttggcgtgggggcatcaatcaaggaaccaaaa
gatatgaaatttatatatgaaggaagcaccgatttctcctgtttgcctacctttggagtt
attatagctcagaaacctatagtaggtggagaattatcagggattcctgggttttcagtc
aacttggaaaaggttctccacggggagcaatacttggagttatataaaccgcttcccaga
gcaggaaacttaaaatgtgaagcagtcattgctgatgtcctagataaaggatccggtcta
gtaattcttgtggatgtctattcttactttgaggaagaacttgtatgttataatcagttc
tcgattttcgttgttggctctggaggcattggtggaaaacggacgtcagacaaagtcaag
gtcgctttagccgtgcctaatagacctcccgatgctgtacttagagataccacctcactt
aatcaggctgctttgtaccgcctcagtggcgactggaatcccttacacattgatcctaac
tttgctggttttgcaggtttcgacaagcccatattacatggattatgtacctttggattt
tctgccaggcatgttttacagcagtatgcagacaatgatgtgtcgagattcaaggcaatt
aaggttcgtttcgcaaaaccagtgtatccaggacagactctacaaactgagatgtggaag
gaaggaaatagaatccatttccaaaccaagatcgaagaaaccggagacgttgtcatttca
aatgcatatgtggatctcataccaacatctgatacttcagcgaagacaccctctgagggt
gggaagctccagagtaccctggtatttgaggagataggtcgccgcctgaaggatatcggg
catgaggtggcggagaaagtaaatgccgtatttgagtggcatatcactaaaggtggacac
actgcagccaagtggactgttgacctaaaaagtggttctggaaaagtgtatcaaggtcct
gcaaaaggctctgctgacgcaaccatcacactttcagatgaagatttcatggacgtggtc
ctgggcaagctcgaccctcagaaggcattctttaatggcagactgaaggccagagggaac
atcatgctgagccagaagcttcagatgattcttaaagactatgccaagctctga
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