KEGG   Novibacillus thermophilus: B0W44_01970
Entry
B0W44_01970       CDS       T04694                                 
Symbol
ligA
Name
(GenBank) DNA ligase (NAD(+)) LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
ntr  Novibacillus thermophilus
Pathway
ntr03030  DNA replication
ntr03410  Base excision repair
ntr03420  Nucleotide excision repair
ntr03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:ntr00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    B0W44_01970 (ligA)
   03410 Base excision repair
    B0W44_01970 (ligA)
   03420 Nucleotide excision repair
    B0W44_01970 (ligA)
   03430 Mismatch repair
    B0W44_01970 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ntr03032]
    B0W44_01970 (ligA)
   03400 DNA repair and recombination proteins [BR:ntr03400]
    B0W44_01970 (ligA)
Enzymes [BR:ntr01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     B0W44_01970 (ligA)
DNA replication proteins [BR:ntr03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     B0W44_01970 (ligA)
DNA repair and recombination proteins [BR:ntr03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     B0W44_01970 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     B0W44_01970 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     B0W44_01970 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      B0W44_01970 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 DNA_ligase_ZBD Nlig-Ia PTCB-BRCT HHH DBF4_BRCT BRCT_2 5_3_exonuc zf-IS66 HHH_8 HMBD Zn_ribbon_NUD
Other DBs
NCBI-ProteinID: AQS54721
UniProt: A0A1U9K3U6
LinkDB
Position
366002..368020
AA seq 672 aa
MNRSEAEKRIVQLRETIEEHNYRYHVLDDPVISDAEYDQLMRELERLEKAFPDLVTEDSP
TQRVGGEPLPYFEKVEHDTPMLSLGNAFDEQELRDFDRRVKRAAGVSGDMAYTCELKIDG
LAISLRYTNGRLTLGATRGDGTTGEDITQNLKTIPAIPLRLKEPVDIEVRGEAYLPKKEF
VRLNEAREKAGVSLFANPRNAAAGSLRQLDPKIAAERALSVFMYSVGDTTGHGIGTQWEM
LDYLVRLGFKVNPERRRVESIDGVIAYVESWRERRAELDYDIDGIVVKVDDFSIQEQLGT
TAKSPRWAIAYKFPAEEAVTIVRAIEVNVGRTGAVTPTAVLEPVTLAGTTVQRASLHNED
LIREKDIRIGDHVVVKKAGDIIPEVIKSIPERRTGEEIVYHMPDECPECGSELVHLEEEV
ALRCINPECPAQTREGIIHFVSRDAMNIDGLGEKVVTQLFNEGLVRSVADLYYLQRDELL
QLERMAEKSVDNLLAAIEKSKENSVEKLIFGLGIRFVGAKAARILAQEFGDLDTLEQADY
EQVLAVEGIGPKIADSIITYFQQPEVKQTLAKLRKAGVNFTYRGPRSEQAVSDSPFSGKT
VVLTGTLQNWSRKEASAKIEALGGNVTGSVSKRTDLVIAGEKAGSKLAKAQKLGIEVWDE
EKLMDVLKELEA
NT seq 2019 nt   +upstreamnt  +downstreamnt
gtgaacagatccgaagcagaaaaaaggatcgtccagctgcgagaaacgatcgaggagcac
aattaccgctaccacgtattagacgatcccgtcatttcggatgcggaatacgatcaactg
atgcgcgaattggagcgattggagaaggcttttcccgatctcgtaaccgaggactccccg
acccaacgggtcggcggtgagcctctcccgtacttcgagaaagtggagcacgacaccccg
atgctcagtctcggcaacgccttcgacgaacaggaactgcgggactttgaccggcgggtg
aagcgggcggccggggtaagcggcgacatggcctacacgtgcgaactgaaaattgacggg
ctggcaatttcacttcgatacacaaacggacggctgacactgggggctacgcgtggtgac
ggtacgacgggtgaagatataacccaaaacttaaagacgattccggccataccgctgcgc
ttgaaggaacctgtagacatcgaagtgcggggggaagcgtacttgccaaaaaaggagttc
gtccgcctgaacgaagcgcgggaaaaagcgggcgtatccctgttcgccaatccgcgtaac
gccgccgccggttcactgcgccaactggacccgaagattgcggccgaacgggccctcagt
gtgttcatgtacagtgtgggagatacgaccggacacggtatcggcacccaatgggaaatg
ctcgactatttggttcgcctcggatttaaagtcaaccccgaacggaggcgagtggagtcc
attgacggagtcatcgcgtacgtggaaagttggcgggaacggcgtgccgaactcgattac
gacatcgacggcattgtggtgaaagtggacgatttctcgatacaggaacagctggggacg
acggcgaagagtccgcgctgggccatcgcctacaagtttcctgcggaagaagcggtgacg
attgtccgagccattgaagtgaacgtcggtcggacaggggccgtgacaccgacggctgtg
ttggaaccggtgacgttggcggggacgactgtacagcgcgcgtctttgcacaacgaagac
ctcatccgggagaaagacatccgtatcggggaccacgtcgtcgtgaaaaaagcaggggat
atcattccggaagtgatcaaatcgatccccgaacggcggacaggcgaagaaatagtgtac
cacatgcccgatgaatgtccggaatgcggcagtgaactcgtccacctggaagaagaagta
gccctccggtgcatcaaccccgaatgtccggcccagacccgggaaggcattatccacttc
gtctcccgggatgcgatgaatatcgatggactgggagaaaaagtggtcacccaactgttt
aacgaaggccttgtccgcagcgtggccgatctgtactaccttcagcgggatgagctgtta
cagttggagcgcatggcagagaagtcggtagataatcttttggcggctatagagaaaagc
aaagaaaattcagtggagaaactgattttcggtctgggcatccgctttgtcggggctaag
gcggcccgcattctcgcccaggaattcggcgacctcgacacactagagcaggccgattac
gagcaagtgctggccgtggaaggcatcggcccgaagatcgccgacagcatcatcacgtat
tttcaacagccggaagtgaaacagacgttggcaaagttgcgtaaagccggtgtgaacttc
acatacagaggaccgcgttcggaacaggcggtgtcagacagtccgtttagcggaaagacc
gtcgtcctgaccggaactttgcaaaactggtcgcgcaaagaagcctccgccaaaatcgaa
gccctcggcggcaatgtcaccggcagcgtcagcaaacgaacagacctcgtcatcgccggg
gaaaaagctggttctaaattggccaaagcgcaaaaactggggattgaagtgtgggatgag
gaaaagttgatggacgtgttgaaggagttggaggcgtaa

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