Neogale vison (American mink): 122902190 Help Entry 122902190         CDS       T08764                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism nvs  Neogale vison (American mink) Pathway nvs01524   Platinum drug resistance nvs04115   p53 signaling pathway nvs04210   Apoptosis nvs04215   Apoptosis - multiple species nvs04217   Necroptosis nvs04620   Toll-like receptor signaling pathway nvs04621   NOD-like receptor signaling pathway nvs04622   RIG-I-like receptor signaling pathway nvs04623   Cytosolic DNA-sensing pathway nvs04625   C-type lectin receptor signaling pathway nvs04657   IL-17 signaling pathway nvs04668   TNF signaling pathway nvs04932   Non-alcoholic fatty liver disease nvs04936   Alcoholic liver disease nvs05010   Alzheimer disease nvs05016   Huntington disease nvs05022   Pathways of neurodegeneration - multiple diseases nvs05132   Salmonella infection nvs05134   Legionellosis nvs05142   Chagas disease nvs05145   Toxoplasmosis nvs05152   Tuberculosis nvs05160   Hepatitis C nvs05161   Hepatitis B nvs05162   Measles nvs05163   Human cytomegalovirus infection nvs05164   Influenza A nvs05165   Human papillomavirus infection nvs05167   Kaposi sarcoma-associated herpesvirus infection nvs05168   Herpes simplex virus 1 infection nvs05169   Epstein-Barr virus infection nvs05170   Human immunodeficiency virus 1 infection nvs05200   Pathways in cancer nvs05203   Viral carcinogenesis nvs05416   Viral myocarditis nvs05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:nvs00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     122902190 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     122902190 (CASP8)    04215 Apoptosis - multiple species     122902190 (CASP8)    04217 Necroptosis     122902190 (CASP8)    04115 p53 signaling pathway     122902190 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     122902190 (CASP8)    04621 NOD-like receptor signaling pathway     122902190 (CASP8)    04622 RIG-I-like receptor signaling pathway     122902190 (CASP8)    04623 Cytosolic DNA-sensing pathway     122902190 (CASP8)    04625 C-type lectin receptor signaling pathway     122902190 (CASP8)    04657 IL-17 signaling pathway     122902190 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122902190 (CASP8)    05203 Viral carcinogenesis     122902190 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     122902190 (CASP8)    05161 Hepatitis B     122902190 (CASP8)    05160 Hepatitis C     122902190 (CASP8)    05164 Influenza A     122902190 (CASP8)    05162 Measles     122902190 (CASP8)    05168 Herpes simplex virus 1 infection     122902190 (CASP8)    05163 Human cytomegalovirus infection     122902190 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     122902190 (CASP8)    05169 Epstein-Barr virus infection     122902190 (CASP8)    05165 Human papillomavirus infection     122902190 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     122902190 (CASP8)    05134 Legionellosis     122902190 (CASP8)    05152 Tuberculosis     122902190 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     122902190 (CASP8)    05142 Chagas disease     122902190 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     122902190 (CASP8)    05016 Huntington disease     122902190 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     122902190 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     122902190 (CASP8)    05416 Viral myocarditis     122902190 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     122902190 (CASP8)    04932 Non-alcoholic fatty liver disease     122902190 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     122902190 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:nvs01002]     122902190 (CASP8) Enzymes [BR:nvs01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      122902190 (CASP8) Peptidases and inhibitors [BR:nvs01002]  Cysteine peptidases   Family C14: caspase family    122902190 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  122902190 NCBI-ProteinID:  XP_044097236 LinkDB All DBs Position 3:13252273..13279609 Genome browser AA seq 485 aa AA seqDB search MNFSKCLYNIGEQLDSDELASLKFLSMDYIPQKKQEPIKDPLMLFQRLQEKRLLEENNLS FLKELLFRINRLDLLVTYLDTSKQEMEQELQIPGRAQISAYRVMLFQISEDVSKLELKSF KFLLSQEISRCKLHDDLNLFDIFIEMEKRVILGERNLDTLKRICDQINRSLLKKITDYEE LRQEQTMIPQRSLDEISNDMSQLLVGEKSLRVLPMSDSPREQNCESETSDKVYQMESKPR GYCLIFNNYDFSIARKEVPKLHSIKDRNGTDLDADALRQTFSELHFEIVPFRDSTAKKIC DVLKSYQSMDHTTRDCFICCILSHGDKGIIYGCDGQGVPICELTSYFTGSKCPSLAGKPK IFFIQACQGDNYQKGIAVETDSEQNEACYESDSCQKRYIPDDADFLLGMATVNNCVSYRN PMEGTWYIQTLCQSLRERCPRGEDILTILTEVNFEVSNKDDRRNMGKQMPQPTFTLRKKL IFPCD NT seq 1458 nt NT seq  +upstreamnt  +downstreamnt atgaatttcagtaaatgcctctataatattggagaacagctggacagtgacgagctggcc tccctcaaattcctgagcatggactacatcccccagaagaagcaggagcccatcaaggat cccctgatgctattccagaggctccaggagaagagactgttggaggaaaacaacctgtcc ttcttaaaggagctgcttttccgaatcaacaggctggacctgctggtcacctacctggac accagcaagcaggagatggagcaagagcttcagatcccgggcagagcccagatctctgct tacagggtcatgctttttcagatttcagaagatgtaagcaaactggaattgaagtccttt aagtttcttttgagccaggagatctctagatgtaaactgcacgatgatttgaatttgttt gatattttcatagagatggagaagagggtcatcctcggggaaagaaatttggacaccctg aaaagaatctgtgaccaaataaacaggagcctgctgaagaaaatcacggattacgaagaa ttaaggcaagagcaaacaatgatccctcaaagaagtctagatgaaatttcaaatgatatg tctcagttgcttgtaggggagaaatccctgagggtactgccaatgtcagactctccaaga gaacagaactgtgaatcagagacatcggacaaagtttaccaaatggaaagcaaacctcga ggatattgtttgatctttaacaattatgactttagcatagcacggaaggaagtgcccaaa cttcacagcattaaggataggaatggaacagacttggatgcagatgctttgcgtcagacc tttagtgagcttcattttgagatcgtgcctttcagagactctacagctaagaaaatctgt gacgttctcaaatcctaccaaagcatggaccacactaccagggactgcttcatctgctgt atcctctcccatggagacaagggcatcatctacggctgtgatggacagggagtccctatc tgtgagcttacctcttacttcactggttctaagtgcccttcccttgcaggcaagcccaaa atcttttttattcaggcttgtcaaggggataactaccagaaggggatcgctgttgagacc gactctgaacagaatgaagcgtgttatgaatcagactcctgtcagaagagatatatccca gacgatgctgactttctgctggggatggccactgtgaataattgtgtttcctaccgaaac cccatggagggaacgtggtatatccagacactttgccagagcctgagagaaagatgtcct aggggagaagatattctcaccatccttactgaagtgaattttgaagtgagcaataaggat gacaggagaaacatgggcaaacagatgccacaaccgaccttcacactgcggaaaaagctc attttcccttgtgactga

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