Neogale vison (American mink): 122902369 Help Entry 122902369         CDS       T08764                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism nvs  Neogale vison (American mink) Pathway nvs04022   cGMP-PKG signaling pathway nvs04068   FoxO signaling pathway nvs04081   Hormone signaling nvs04140   Autophagy - animal nvs04150   mTOR signaling pathway nvs04151   PI3K-Akt signaling pathway nvs04152   AMPK signaling pathway nvs04211   Longevity regulating pathway nvs04213   Longevity regulating pathway - multiple species nvs04722   Neurotrophin signaling pathway nvs04910   Insulin signaling pathway nvs04920   Adipocytokine signaling pathway nvs04923   Regulation of lipolysis in adipocytes nvs04930   Type II diabetes mellitus nvs04931   Insulin resistance nvs04932   Non-alcoholic fatty liver disease nvs04935   Growth hormone synthesis, secretion and action nvs04960   Aldosterone-regulated sodium reabsorption nvs05010   Alzheimer disease nvs05206   MicroRNAs in cancer nvs05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:nvs00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     122902369 (IRS1)    04022 cGMP-PKG signaling pathway     122902369 (IRS1)    04151 PI3K-Akt signaling pathway     122902369 (IRS1)    04152 AMPK signaling pathway     122902369 (IRS1)    04150 mTOR signaling pathway     122902369 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     122902369 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     122902369 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     122902369 (IRS1)    04923 Regulation of lipolysis in adipocytes     122902369 (IRS1)    04920 Adipocytokine signaling pathway     122902369 (IRS1)    04935 Growth hormone synthesis, secretion and action     122902369 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     122902369 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     122902369 (IRS1)   09149 Aging    04211 Longevity regulating pathway     122902369 (IRS1)    04213 Longevity regulating pathway - multiple species     122902369 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     122902369 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     122902369 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     122902369 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     122902369 (IRS1)    04932 Non-alcoholic fatty liver disease     122902369 (IRS1)    04931 Insulin resistance     122902369 (IRS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  122902369 NCBI-ProteinID:  XP_044097656 UniProt:  A0A8C7A7D0 LinkDB All DBs Position 3:complement(35907492..35967652) Genome browser AA seq 1237 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASMVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGSSTLAAPN GHYILPRGGNGHRYIPGTGLGTSPALAGDEAASATDLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHPLDRRGGHHR PDASTLHTDDGYMPMSPGVAPVPSSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDIGGGPSSSTGAAPSGGSYGKLWTNGVGGHHGSALPHPKLPGESGSS KLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGELEES ARHQHLRLSSSSGRLLYAAAAEDSSSSTSSDSLGGGYCGVRPDPGLPHIHHQVLQPHLPR KVDTAAQTNSRLARPTRLSLGDPKASTLPRVREQQQQPTLLHPPEPKSPGEYVNIEFGSD QPGYLSGPVASRSSPSVRCPSQLQPAPREEETGTEEYMNMDLGPGRRATWQESAGVQPGR VGPAPPGAASMCRPTRAVPSTRGDYMTMQMGCPGQSYVDTSPVAPISYADMRTGVVEEAG LPGATAAAPSSSAASASPTTAPQKAGELVARSSLLGAPQGPGAMSAFTRVNLSPNRNQSA KVIRADPQGCRRRHSSETFSSTPSATRAGNTVPFGGGAAVGDSGGGSSSTEDMKRHSSAS FENVWLRPGELGGAAKEPAPVCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQPQPPPPQ PPHQPLGSSESSSASRSSEDLSAYASISFQKQPEDLQ NT seq 3714 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctcccgagaccgacggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcggggggc ccggcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctcgagagctgtttcaacatcaacaagcgggccgactccaagaac aagcacctggtggccctttacacccgggacgagcactttgccatcgcggcggacagcgag gccgagcaggacagctggtaccaggccctcctgcagctgcacaaccgggccaagggccac cacgacggggcggcagcccccggggcaggaggaggtgggggcagctgcagtggcagctct ggcctcggggaggctggggaggacttgagttacggggacgtgcccccaggacctgcgttc aaggaggtctggcaggtgatcctgaaacccaagggcctgggtcagacaaagaacctgatt ggtatttaccgtctctgcctgaccagcaagaccatcagcttcgtgaagctgaactcggag gcggcggctgtggtgctgcagctgatgaacatcagacgctgcggccactcggagaacttc ttcttcatcgaggtgggccgttccgcagtgacgggacctggggagttctggatgcaggtg gatgactctgtggtggcccagaacatgcacgagacaattctggaggccatgagggccatg agcgatgagttccgtcctcgaagtaagagccagtcctcctccaactgctccaaccccatc agcgtccccctgcgcaggcaccatctcaacaaccccccgcccagccaggtggggctgacg cgccgctctcgcacggagagcatcaccgccacctctccggccagcatggtgggcggcaag cagggttccttccgtgtgcgcgcgtccagtgatggggaaggcaccatgtcccggccggcc tcggtggacggcagccccgtgagtcctagcaccaacaggacccacgcccaccggcatcgc ggcagctcccggctacaccctcctctcaaccacagccgctccatccccatgccttcctct cgctgctcaccttctgccaccagcccagtcagtctgtcgtccagcagcaccagtggccac ggctccacctcggactgtcttttcccacggaggtctagtgcttccgtgtcgggatccccc agcgatggcggcttcatctcctccgatgagtatggctccagcccttgcgatttccgaagt tccttccgcagtgtcaccccggattccctgggccacaccccaccagcccgaggcgaggag gagctgagcaactacatctgcatggggggcaaagggtcctccaccctcgccgcccccaat ggtcactacattttgcctcggggtggcaacggtcaccgctacatcccaggaactggtttg ggcacgagcccagccctggctggggatgaagcagccagtgctacagatctggataatcgg ttccgaaagcggactcactctgctggcacgtcccctaccatttcccaccagaagacccca tcccagtcctctgtggcttccattgaggaatacacggagatgatgcctgcctacccacca ggaggtggcagtggaggccgactgcctggctaccggcactctgccttcgtgcccacccac tcctaccccgaggagggtctggaaatgcaccctttggaccggcgtggaggccaccaccgc ccagacgcctccactctccacactgatgatggctacatgcccatgtccccaggagtggcg ccagtgcccagcagccgaaagggcagtggggactacatgcccatgagccccaagagtgtg tctgcaccccagcagatcatcaacccaatcagacgccatccccagcgagtggaccccaat ggctacatgatgatgtccccgagcggcagctgctcccctgacattggaggtgggcccagc agtagcacgggcgctgccccttctgggggcagctatggcaagctgtggacaaatggggtt ggggggcaccatggttctgccctaccacatcccaagctgcctggggagagtggcagcagc aagctcttgtcttgtactggtgattacatgaacatgtcgccagtgggggactccaacacc agcagcccctccgactgctactatggcccggaagacccccagcacaagccagttctctcc tactactcattgccaaggtcctttaagcacacgcagcgccctggggagctggaggagagt gctcggcaccaacaccttcgcctttcctccagctctggtcgccttctctatgctgcagcg gcagaagattcctcctcctccaccagcagcgacagcctgggagggggatactgtggggtg aggccagatcctggcctcccacatatccaccatcaggtcctgcagcctcatctgcctcga aaggtggacacagctgcccagaccaacagccgcctggctcggcccacgaggctgtctctg ggggatcccaaggccagcaccttacctcgggtacgagagcagcagcaacagccgaccctg ctgcaccctccagagcccaagagcccgggggaatatgtgaatattgaatttgggagtgat cagccgggttacttgtctggtcctgtggcttcccgcagctcgccttctgtcaggtgtccg tcccagctccagccagctccccgagaggaagagactggcacggaggaatacatgaacatg gacctggggccgggccggagggcgacctggcaggagagcgctggggtccagccaggcaga gtgggccctgcacctcctggagctgctagcatgtgccggcctacccgggcagtgcccagc acccggggggactacatgaccatgcagatgggttgtcccgggcagagctacgtggacacc tcaccagttgcccccatcagctatgctgacatgaggacaggcgttgtggaggaggccggc cttccaggggccacagcagcagctccctcatcctctgcagcctctgcttcccccaccact gcgcctcagaaagcaggggagctggtggctcgctcttccctgctgggagccccacaggga cctggggccatgagcgccttcacccgggtcaacctcagtcccaaccggaaccagagtgcc aaagtgatccgtgcagacccacaagggtgccggaggaggcatagctctgagaccttctcc tccacacctagtgccacccgggcgggcaacacggtgccctttggagggggggcagctgta ggggacagcggtggtggcagcagcagcacggaggacatgaaacgccacagttctgcttcc tttgagaatgtgtggctgaggcctggggagcttgggggagctgccaaggagccggcccca gtgtgtggggctgctggcggtttggagaatgggcttaactacatagacctggatctggtc aaggacttcaaacagcgccctcaggagcgcccccctcaaccgcagccgcccccgccccaa ccccctcatcagcctctgggcagcagtgagagcagctcagccagccgctccagtgaggat ttaagcgcctatgccagcatcagtttccagaagcagccagaggacctccagtag

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