Neogale vison (American mink): 122904661 Help Entry 122904661         CDS       T08764                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism nvs  Neogale vison (American mink) Pathway nvs00230   Purine metabolism nvs01100   Metabolic pathways nvs01522   Endocrine resistance nvs04015   Rap1 signaling pathway nvs04020   Calcium signaling pathway nvs04022   cGMP-PKG signaling pathway nvs04024   cAMP signaling pathway nvs04062   Chemokine signaling pathway nvs04072   Phospholipase D signaling pathway nvs04081   Hormone signaling nvs04082   Neuroactive ligand signaling nvs04114   Oocyte meiosis nvs04211   Longevity regulating pathway nvs04213   Longevity regulating pathway - multiple species nvs04261   Adrenergic signaling in cardiomyocytes nvs04270   Vascular smooth muscle contraction nvs04371   Apelin signaling pathway nvs04540   Gap junction nvs04611   Platelet activation nvs04713   Circadian entrainment nvs04714   Thermogenesis nvs04720   Long-term potentiation nvs04723   Retrograde endocannabinoid signaling nvs04724   Glutamatergic synapse nvs04725   Cholinergic synapse nvs04727   GABAergic synapse nvs04750   Inflammatory mediator regulation of TRP channels nvs04911   Insulin secretion nvs04912   GnRH signaling pathway nvs04913   Ovarian steroidogenesis nvs04914   Progesterone-mediated oocyte maturation nvs04915   Estrogen signaling pathway nvs04916   Melanogenesis nvs04918   Thyroid hormone synthesis nvs04921   Oxytocin signaling pathway nvs04923   Regulation of lipolysis in adipocytes nvs04925   Aldosterone synthesis and secretion nvs04926   Relaxin signaling pathway nvs04927   Cortisol synthesis and secretion nvs04928   Parathyroid hormone synthesis, secretion and action nvs04934   Cushing syndrome nvs04935   Growth hormone synthesis, secretion and action nvs04970   Salivary secretion nvs04971   Gastric acid secretion nvs04972   Pancreatic secretion nvs04976   Bile secretion nvs05032   Morphine addiction nvs05142   Chagas disease nvs05146   Amoebiasis nvs05163   Human cytomegalovirus infection nvs05166   Human T-cell leukemia virus 1 infection nvs05200   Pathways in cancer nvs05207   Chemical carcinogenesis - receptor activation nvs05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:nvs00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     122904661 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     122904661 (ADCY1)    04371 Apelin signaling pathway     122904661 (ADCY1)    04020 Calcium signaling pathway     122904661 (ADCY1)    04072 Phospholipase D signaling pathway     122904661 (ADCY1)    04024 cAMP signaling pathway     122904661 (ADCY1)    04022 cGMP-PKG signaling pathway     122904661 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     122904661 (ADCY1)    04081 Hormone signaling     122904661 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     122904661 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     122904661 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122904661 (ADCY1)    04062 Chemokine signaling pathway     122904661 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     122904661 (ADCY1)    04923 Regulation of lipolysis in adipocytes     122904661 (ADCY1)    04912 GnRH signaling pathway     122904661 (ADCY1)    04913 Ovarian steroidogenesis     122904661 (ADCY1)    04915 Estrogen signaling pathway     122904661 (ADCY1)    04914 Progesterone-mediated oocyte maturation     122904661 (ADCY1)    04921 Oxytocin signaling pathway     122904661 (ADCY1)    04926 Relaxin signaling pathway     122904661 (ADCY1)    04935 Growth hormone synthesis, secretion and action     122904661 (ADCY1)    04918 Thyroid hormone synthesis     122904661 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     122904661 (ADCY1)    04916 Melanogenesis     122904661 (ADCY1)    04925 Aldosterone synthesis and secretion     122904661 (ADCY1)    04927 Cortisol synthesis and secretion     122904661 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     122904661 (ADCY1)    04270 Vascular smooth muscle contraction     122904661 (ADCY1)   09154 Digestive system    04970 Salivary secretion     122904661 (ADCY1)    04971 Gastric acid secretion     122904661 (ADCY1)    04972 Pancreatic secretion     122904661 (ADCY1)    04976 Bile secretion     122904661 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     122904661 (ADCY1)    04727 GABAergic synapse     122904661 (ADCY1)    04725 Cholinergic synapse     122904661 (ADCY1)    04720 Long-term potentiation     122904661 (ADCY1)    04723 Retrograde endocannabinoid signaling     122904661 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     122904661 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     122904661 (ADCY1)    04213 Longevity regulating pathway - multiple species     122904661 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     122904661 (ADCY1)    04714 Thermogenesis     122904661 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122904661 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     122904661 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122904661 (ADCY1)    05163 Human cytomegalovirus infection     122904661 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     122904661 (ADCY1)    05142 Chagas disease     122904661 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     122904661 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     122904661 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     122904661 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     122904661 (ADCY1) Enzymes [BR:nvs01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      122904661 (ADCY1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 Motif Other DBs NCBI-GeneID:  122904661 NCBI-ProteinID:  XP_044101652 LinkDB All DBs Position 4:complement(136862392..136952800) Genome browser AA seq 1138 aa AA seqDB search MAGAPRGRGGGGGGGGGGGGAGEPGGAERAAGPGGRRGLRPCGEEFACPELEALFRGYTL RLEQAATLKALAVLSGLAGALALAELLGAPGPAAGLARGSHPAHCVLFLALLVVTNVRSL QAPQLQQVGQLALLFSLTFALLCCPFALGGPAGTHAGAASGTAAADHGVWQLLLVTFVSY ALLPVRSLLAVGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLSVNMYGVFVRVL AERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKI YIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCY YCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKW QYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKAHNIETF FIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDD KRRALRTASEKLRNRSSFSANVVHTAPGTRVNRYIGRLLEARQMELEMADLDFFTLKYKH AERERKYHQLQDDYFTCAVVLALVLAAVFGLVYLLIIPQSVVVLLLLVFCICFLVACVLY LHVTRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSSPNGSLMVLAPGG RNALLPAAPCESAPHALLCGLVGTLPLAVFLRVSSLPKMILLFVLTASYILVLELSGYTR ASGGGAVSGRSFEPIVAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMERVKLDN KRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVEC LRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLVPTTGSKAKKCISSHLSTLAD FAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTG VQGRIQVTEEVHRLLRKGTYRFVCRGKVSVKGKGEMLTYFLEGRTNRNGSQARSLNAERK MCAYGRPGLQTRLGTGPPPMAPMAGPPVRAGLGALQGSGLPPGPHGQHPPPGAAGKEA NT seq 3417 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggaggcggcggcggcggaggcggaggcggcggc gcgggcgagcccgggggcgccgagcgggcggcggggccgggcggccggcgcgggctgcgg ccgtgcggtgaggagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctg cggttggagcaggcggccacgctgaaggcgctggccgtgctcagcgggctggcgggcgcg ctggcgctggcggagctgctgggcgcgccggggcccgcggccggcctggccaggggctcg caccccgcgcactgcgtgcttttcctggcgctgctcgtggtcaccaacgtgcgctcgctg caggcgccgcagctgcagcaggtcggccagttggcgctgctgttcagcctcaccttcgcg ctgctctgctgccccttcgcgctcggcgggcccgcgggcacccacgccggcgcggcttcg gggacggcggccgccgaccacggcgtctggcagctccttttggtcaccttcgtgtcctat gccctgctgcccgtgcgcagcctgctggctgtcggcttcgggctcgtggtggccgcctca cacttgctggtcacggccaccttggtgcccgccaagcgcccgcgtctctggaggacgctc ggtgccaacgccctgctcttcctcagtgtgaacatgtacggggtgtttgtgcgggtcctg gccgaacgctcccaaaggaaagccttcctgcaggcccggaactgcatcgaggaccggctt aggctggaggatgagaacgagaagcaggagcggctgcttatgagtcttctgccccggaat gttgccatggagatgaaggaggacttcctgaagccccccgagaggattttccacaagatc tacatccagcggcacgacaatgtgagcatcctcttcgcggacatcgtgggcttcacgggc ctggcgtcgcagtgcacggcccaggagctggtgaaactcctgaacgagctcttcggcaag tttgacgaactggctacggagaaccactgccgccgcatcaagatcctcggggactgctac tactgtgtgtcgggcctcacccagcccaagaccgaccacgcccactgctgcgtggagatg gggctggacatgattgacaccatcacgtcggtggccgaggccacggaggtggatctgaac atgcgtgtggggctgcacaccggccgggtcctctgcggggtcctcggcctgcgcaagtgg cagtatgacgtgtggtccaatgacgtgacgctggccaatgtcatggaggccgccggcctg cccgggaaggtccacatcacgaagacgaccctggcttgcttgaacggggactatgaggtg gagccggggcacgggcacgagaggaacagtttcctaaaggctcacaacatcgagaccttc ttcatcgtgccgtcacaccggcggaagatatttccagggctgatcctgtccgacatcaag cctgccaagaggatgaagttcaagaccgtgtgttacctgctggtgcagcttatgcactgt cggaagatgttcaaggcggagatccccttctccaacgtcatgacctgcgaggacgatgac aagcggagggcgttgagaaccgcgtcggagaaactcagaaaccgctcgtccttctccgct aacgtcgtgcacaccgctccgggcacgcgggtcaacaggtacatcggccgcctcctggag gcgcgccagatggagctagagatggccgacctggacttcttcaccctgaagtacaagcac gcggagcgtgagcgcaagtaccaccagctgcaggacgactacttcacctgtgctgtggtg ctcgcgcttgtcctggctgccgtgttcggcctcgtttacctgctcatcatcccacagagc gtggttgtcctgctgctgctggtgttctgcatctgcttcctggtggcctgtgtcctgtac ctgcacgtcactcgcgtccagtgttttccaggatgcctgaccatccagatccgcaccgtc ttgtgtattttcatcgtggtcctaatttactccgtggcccaaggctgtgtggtgggctgc ctgccctgggcctggagctccagccccaacgggtccctcatggtcctggcgcccggcggc cggaatgccctgctgcccgccgcgccctgcgagtcggccccccacgccctgctgtgcggc ctcgtgggcaccctcccgctggctgtcttcctgcgggtgtcctcgctgcccaagatgatc ctgctgtttgtgctcacagcgtcctacatcctggtcctggagctcagcgggtacacccgg gcctcggggggcggcgcggtgtctgggcgcagcttcgagccgatcgtggccatcctgctg ttctcctgcacgctggccctgcacgcgcggcaggtggacgtaaagctgcggctggattac ctgtgggcggcacaggcggaggaggagagggacgacatggagagggtgaagctggacaac aagcggatcctcttcaacctcctgccggcccacgtcgctcagcacttcctcatgtccaac ccccggaacatggacctgtactaccagtcctactcgcaggtgggcgtcatgtttgcctcc atccccaacttcgacgacttctacatcgagctggacggcaacaacatgggtgtggagtgc ctgcgcctcctgaacgagatcatcgctgactttgacgagctcatggacaaagacttttac aaggacctggagaagatcaagaccattgggagcacctacatggctgcggtggggctagtg cccacgacagggtccaaggcaaagaagtgcatctcctcacacctcagcacgctggccgac ttcgccatcgagatgtttgacgtcctggacgagatcaactaccagtcttacaacgacttt gtgctccgcgtcggcatcaacgttggccccgtggtggccggggtgattggggctcgaagg ccacagtatgacatttggggaaacacggtcaatgtggccagtcggatggacagcaccggt gtccagggcagaatccaggtgaccgaggaggttcaccggctgctgcgaaagggcacctac cgcttcgtgtgccgtgggaaggtcagcgtcaagggcaagggtgagatgctaacgtacttc ctggaaggccggaccaatagaaatggctcccaggccaggtccctgaacgcagagcggaaa atgtgtgcttacgggcgacctggcctccagaccagactgggcacaggcccgcccccaatg gccccaatggccggtcccccagtcagagctgggctgggggctctgcagggctcggggctc ccgccgggccctcatggccagcacccgccccccggagcagctgggaaggaggcttag

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