Neogale vison (American mink): 122906161
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Entry
122906161 CDS
T08764
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X1
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs01524
Platinum drug resistance
nvs03440
Homologous recombination
nvs03460
Fanconi anemia pathway
nvs04120
Ubiquitin mediated proteolysis
nvs04151
PI3K-Akt signaling pathway
nvs05206
MicroRNAs in cancer
nvs05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
122906161 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
122906161 (BRCA1)
03460 Fanconi anemia pathway
122906161 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
122906161 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
122906161 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
122906161 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
122906161 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
nvs01009
]
122906161 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
nvs04121
]
122906161 (BRCA1)
03036 Chromosome and associated proteins [BR:
nvs03036
]
122906161 (BRCA1)
03400 DNA repair and recombination proteins [BR:
nvs03400
]
122906161 (BRCA1)
Enzymes [BR:
nvs01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
122906161 (BRCA1)
Protein phosphatases and associated proteins [BR:
nvs01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
122906161 (BRCA1)
Ubiquitin system [BR:
nvs04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
122906161 (BRCA1)
Multi subunit type E3
BRCC complex
122906161 (BRCA1)
Chromosome and associated proteins [BR:
nvs03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
122906161 (BRCA1)
DNA repair and recombination proteins [BR:
nvs03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
122906161 (BRCA1)
BRCA1-A complex
122906161 (BRCA1)
BRCA1-B complex
122906161 (BRCA1)
BRCA1-C complex
122906161 (BRCA1)
BRCA complex
122906161 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
122906161 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-C3HC4_3
zf-RING_2
zf-RING_5
RING_XB3-XBAT31
BRCT_2
zf-Nse
zf-RING_6
zf-ANAPC11
zf-RING_10
Motif
Other DBs
NCBI-GeneID:
122906161
NCBI-ProteinID:
XP_044103765
LinkDB
All DBs
Position
5:19439469..19507920
Genome browser
AA seq
1884 aa
AA seq
DB search
MPQNSVEQEEMDLPADRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLK
LLNQRKGPSKCPLCKNDITKRSLQESTRFSQLVEELLKIIHAFELDTGLQFANSYNFTKK
ENNSPEHLKEEVSIIQSMGYRNRAKRLRQNEPENPTLQETSLSVQLSDLGILRSLRTKQQ
IQPQNKSVYIELGSDSSEDTVNKASYCSVGDDELLQITPQGSRAEASLNPAKKAACEISE
DITNSERHQSDNKDLTTTEKHATEKHPEKYQGISVSDLHVEPCGTNTHASSLQHENSSLL
LTKDRMNVEKAEFCNKSKQPALARSQQSRWVESKETCNDRQTPSTERKVLLKADPLCGRR
EPKKQKPLGSDSPRDSQDVPWITLNSSIQKVNEWFSRSDEMSTSDDDSHDGGSESRTEVA
GAVEVPNEVHGCSGSSEKIDLMASEPQDALIRERERVHTKSVESNIEDKIFGKTYRRKAS
LLNVSHMSEDLLIGVCAVEPQTVQAHPLTSKAKHKRRTTAGLHPEDFIKKVDLAIVPKTP
EKLVEGTDQLERSGHVTKIRNNGPEDEIKGDCVQTERNANPTESLEKESAFRSRAEPISS
SITKMELELNSSGLKALKKNRLRRKSSTRHGCALEFVVSRNPSPPDRSELQIDSCSSSEE
MKKEPADQMPVRRSKTLQLLEEEEPAAGPKKGRKPGEQIHKRLASHAFPELSLTNVPGCF
ANCSSSNKPQESVHPSIRREDIEESRRTTQVSGSTRDPKELLLSGGRGLQIERSVENTSV
SLVPDTDCGTQDSISLLEADTLRKAKTAPNQRASLCTVIEHPKETIHSHSKDTRNGPEGF
ADPLTCEDNHTQETSIEMEESELDTQYLRNTFKVSNRQSFALFSNPRDPENDCAMVYAHS
GALRKQSPKVTPECGQKEENQGRQESEIKHAQAVPAMAGFSAVIQEAQKPEDYAKCSLKG
GSNLCQSSQFRGKETELLIANNCGFSQNPYHIPPLPPIRSGIKTLCNKNLSEERFEQHSM
SPERAVGNESVIQSTVSTISQNNIRESSLREVSSSSVNEVGSSTNEVGSSTNEVGSSGEN
MQAELGRNRGPQLNAKLRLGLMQPEVCNQSLPVRNCKDPEMKRQGENEGIVLSVNADFSP
CLISDNPEQPMGSSHASQVCSETPDDLLNGDKIKGKISFAESDVKERSAVFSKNVQKGEF
RRSPSPLDDTHLAQGQKRGARKLESSEENTSSEEEELPCFQHLLFGKVANTPSQATSHNV
VAAEGLSKKTEENLDSQKSSLSDLSNQVPSAKASQEHHLSEETRCSGSLFSSQCSALEDM
TVNTNTQDPFLMFDAPSEQVRHQSENLDALSDKELVSDDDERELGLEEDNHEEQSVDSDL
GEVASGYQSETSFSEDCSRLSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHGSQP
SRSSPSLVADSCAPEDLLNPEQNTSEKAVFTSEKSSDYPKSQNPESLSADKYQVSLDSST
GKNKEPGMRRSSPSQSRLLDTRWYVHSCPRSLQDTDCPSQKELIKVVSVDEQQASRSEAR
DFMEQPYLPRPDLEGTPYLESGISLFDDPESDASTDRAPEPAHVSRMPAATSALKLPQFQ
VEESAKSTAAVHIANTAGYDKREDSVGREKPEVISSIKRVNRRISMVASGLTPKECMLVH
KFARKHHITLTNQISEETTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKER
KMLDEHDFEVRGDVVNGRNHQGPKRARESRDRKIFRGLEVCCYGPFTNMPTDQLEWMLRL
CGASVVKEPSLFPHSKGAHPVVVVQPDAWAEDSGFHAIGQMCEAPVVTREWVLDSVALYQ
RQELDTYLIPQIPRAAAHSSQPCV
NT seq
5655 nt
NT seq
+upstream
nt +downstream
nt
atgcctcaaaattcagtggaacaggaagaaatggatttacctgcggatcgtgttgaagaa
gtacaaaatgtccttaatgctatgcagaaaatcttagagtgtccaatctgtctggagttg
atcaaagagcctgtttccacaaagtgtgatcacatattttgcaaattttgtatgctgaaa
cttctcaaccagaggaaaggaccttccaagtgtcctttgtgtaagaatgatataaccaaa
agaagcctacaagaaagtacaagatttagtcaactagttgaagagctgttgaaaatcatt
catgcttttgagcttgacacgggattgcagtttgcaaacagctataactttacaaaaaag
gaaaataactctccagagcacctaaaggaggaagtttctatcatccaaagtatgggctat
cgaaaccgtgccaaaagacttcgacagaatgaacctgaaaaccccaccttgcaggaaacc
agtcttagtgtccaactctctgaccttggaattctgagatctctgaggacaaagcagcag
atacagcctcagaataagtctgtctacattgaattgggatctgattcttctgaagataca
gttaataaggcaagttactgcagtgtgggagatgatgagttgttacaaatcacccctcaa
ggatccagggctgaagccagtttgaatcctgcaaaaaaggctgcttgtgaaatttctgag
gatataacaaatagtgaacgccatcaatccgataataaagatttgaccaccactgagaag
catgcaactgagaagcatccagaaaagtatcagggtatttctgtttcagacttgcatgtg
gagccatgtggcacaaatactcatgccagctcattacagcatgagaacagcagtttatta
ctcactaaagacagaatgaatgtagaaaaggctgaattctgtaataaaagcaaacagcct
gccttagcaaggagccaacagagcagatgggtcgaaagtaaggaaacatgtaatgatagg
cagactcccagcacagagagaaaggtacttctgaaagctgatcccctgtgtgggagaaga
gaaccgaagaagcagaaacctctaggctctgacagtcctagagattcccaagatgttcct
tggataacactgaatagtagcatacagaaagtgaatgagtggttttccagaagcgatgaa
atgtcaacttctgatgatgactcacatgacgggggatctgaatcgaggaccgaagtagct
ggtgcagtagaagttccaaacgaagtgcacggatgttccggttcctctgagaaaatagac
ttaatggccagcgagcctcaggatgctctgatacgtgaacgcgaaagagtccacaccaag
tccgtagagagtaacatcgaagataaaatatttgggaaaacctaccggaggaaggcaagc
ctccttaacgtgagccacatgagcgaagatctgcttataggagtgtgtgctgtagaacct
cagacagtgcaagcccaccccctcacgagtaaagcaaagcataaacggagaactacagca
ggccttcatcctgaggattttatcaagaaagtagatctggccatcgttccaaagactcct
gaaaagctagttgagggaaccgaccaactcgagcgaagtggtcacgtgacgaagattaga
aataatggtcccgaggatgaaataaaaggtgattgtgttcagaccgagagaaatgctaac
ccaacagaatccctggaaaaagaatctgctttcagaagcagagctgaaccgataagcagc
agtataaccaagatggaactggaattaaatagctccggtttgaaagcccttaagaagaac
aggctgcggaggaagtcctccaccaggcacggctgtgcgcttgaattcgtagtcagtcga
aatccaagcccgcctgatcgcagtgaactgcagatcgatagctgttctagcagtgaggag
atgaagaaagaacctgcggaccagatgccagtcagacgcagcaaaacgcttcagctcctg
gaagaggaagaacctgcagctggacccaagaagggcaggaagccaggtgaacagatacat
aagagacttgccagtcatgcttttccagagctgagtttaacaaacgtaccggggtgcttt
gctaactgttcaagttctaataaacctcaagagtctgtccaccctagcatccgaagagaa
gacatagaagagagccgaagaacgactcaagtgtctggtagtaccagagatcccaaagag
ctgctactgagtggaggaagaggtttgcaaattgaaagatctgtagagaataccagtgtt
tccttggtacctgatacggattgtggcactcaggacagtatctcgttgctggaagccgac
accttaaggaaggcaaaaactgcaccaaatcaacgtgcgagtctgtgcacagtaattgaa
caccccaaggaaactatccacagtcattctaaagatactagaaacggcccagaaggcttt
gcggatccactgacgtgcgaagataaccacacccaggagacaagcatagaaatggaagag
agtgaacttgatacacagtatttacgcaacacgttcaaggtttcaaaccgtcagtcattt
gctctgttttcaaatccaagagatccagaaaacgactgtgcaatggtctatgcccactct
ggggccttaaggaaacaaagtccaaaagtcactcctgaatgtggacaaaaagaagagaat
cagggaaggcaagagtctgaaatcaagcatgcgcaggcagttcctgcaatggcgggcttt
tctgcagttattcaggaagctcagaagccagaagattatgccaaatgtagcctcaaagga
ggctctaacctttgtcagtcatctcagttcagaggcaaggaaactgaactccttattgca
aataactgtggattttcccaaaatccttatcatataccaccacttcctcccatcagatca
ggtattaaaactctttgtaacaaaaacctgtcagaagaaaggtttgagcagcattcaatg
tcaccagaaagagcagtgggaaatgagagcgtcattcagagtacagtgagcacaattagc
caaaataacatcagagaaagctcgttgagagaagtcagctcaagcagtgttaatgaagta
ggttccagtacaaacgaagtaggctctagtactaatgaagtaggttccagtggagaaaac
atgcaggcagaactaggtagaaaccggggacctcaattaaatgctaagctcaggttaggt
cttatgcaacctgaagtctgtaaccaaagccttcctgtaagaaattgtaaagatccggaa
atgaaaaggcaaggagaaaatgaaggtatagttctgtcagttaatgcagatttctcccca
tgtctaatttcggataaccccgaacaacctatgggaagtagtcacgcttctcaggtttgt
tcggagacacccgatgacctgttaaatggtgacaaaataaaggggaaaatcagctttgct
gaaagtgacgttaaagaaagatctgctgtctttagcaaaaatgtccagaaaggagaattc
agaaggagccctagccctttagacgatacacatttggcccaggggcagaaaagaggggcc
aggaaattagagtcctcagaagagaacacgtctagtgaggaggaagagcttccctgcttc
caacacttactatttggcaaagtagccaacacaccttctcaggctaccagtcacaatgtt
gttgctgcagagggtctgtctaaaaaaacagaggagaacctagactcacagaagagtagt
ttaagtgacctcagtaaccaggtaccatcagcaaaagcatcccaggaacatcacctgagt
gaggaaacgaggtgttctggtagcttattctcttcacagtgcagtgctttggaagacatg
accgttaatacaaatacccaggatcctttcttgatgtttgatgctccttctgaacaagtg
aggcatcagtctgaaaacctggatgctctgagtgacaaggaattggtttcagatgatgat
gaaagggaacttggtctggaagaagataatcacgaagaacagagtgtggattcggactta
ggtgaagtggcatccgggtaccagagtgaaacaagcttctctgaagactgttcgagattg
tcctctcagagtgatattttaaccacacagcagagggataccatgcaagataacctgata
aagctccagcaggaaatggccgaactggaagctgtgttagagcagcacgggagccagcct
tctcgaagctccccttctctcgtggcagattcttgtgccccggaggatctgctcaatccg
gagcaaaacacatcagaaaaagcagtattcacttcagagaaaagtagcgactatcctaaa
agccagaatcccgaaagcctttctgcggacaaatatcaggtatctctggatagttccacc
ggtaaaaataaagaaccaggaatgagaaggtcttccccctctcagtcccggttgttagat
acgaggtggtatgtgcacagctgcccaaggagtcttcaggacacggactgcccttctcaa
aaggagctcattaaggttgtcagtgtagacgagcaacaagcgagtaggtcagaagcgcga
gatttcatggagcagccttatttgccaagaccagatctggagggaaccccttaccttgag
tctggaatcagcctctttgatgaccctgagtctgacgcctctacagacagagccccagag
ccagctcatgttagccgcatgccagctgcaacctctgcattgaaattaccccaatttcaa
gttgaagaatcagccaagagtacagctgctgtccatattgctaatactgctgggtacgat
aagagggaagacagtgtgggcagggagaagccagaagttatatcttcaataaaaagagtc
aacagaagaatatctatggtggcatcaggcttaaccccaaaagaatgtatgcttgtgcac
aagtttgccagaaaacaccacatcactttaactaatcaaatttccgaagagactactcat
gtcatcatgaaaacagatgctgagtttgtgtgcgaacggacactgaaatattttctgggt
attgcaggaggaaaatgggtagttagctatttctgggtgacacagtcaattaaagaaagg
aagatgctagatgagcatgattttgaagtcagaggagacgttgtgaatggaagaaaccac
cagggtccaaagagagcaagagaatcccgggacaggaagatcttcaggggcctagaagtc
tgttgctatgggccctttaccaacatgcctacagatcaactcgagtggatgctgcgcctc
tgtggggcttctgtggtgaaggagccctcgttattccctcacagcaagggtgctcacccc
gtggtagtcgtgcagccggacgcctgggcagaggacagtggcttccatgcgattgggcag
atgtgtgaagcacctgtggtgactcgagagtgggttttggacagtgtagccctctaccag
cgtcaggagctggacacctacctgatcccgcagatccccagagccgccgctcactccagc
cagccgtgcgtgtag
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integrated database retrieval system
