Neogale vison (American mink): 122907240 Help Entry 122907240         CDS       T08764                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism nvs  Neogale vison (American mink) Pathway nvs04022   cGMP-PKG signaling pathway nvs04068   FoxO signaling pathway nvs04081   Hormone signaling nvs04140   Autophagy - animal nvs04152   AMPK signaling pathway nvs04211   Longevity regulating pathway nvs04213   Longevity regulating pathway - multiple species nvs04910   Insulin signaling pathway nvs04920   Adipocytokine signaling pathway nvs04923   Regulation of lipolysis in adipocytes nvs04930   Type II diabetes mellitus nvs04931   Insulin resistance nvs04932   Non-alcoholic fatty liver disease nvs04935   Growth hormone synthesis, secretion and action nvs05010   Alzheimer disease nvs05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:nvs00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     122907240 (IRS2)    04022 cGMP-PKG signaling pathway     122907240 (IRS2)    04152 AMPK signaling pathway     122907240 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     122907240 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     122907240 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     122907240 (IRS2)    04923 Regulation of lipolysis in adipocytes     122907240 (IRS2)    04920 Adipocytokine signaling pathway     122907240 (IRS2)    04935 Growth hormone synthesis, secretion and action     122907240 (IRS2)   09149 Aging    04211 Longevity regulating pathway     122907240 (IRS2)    04213 Longevity regulating pathway - multiple species     122907240 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     122907240 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     122907240 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     122907240 (IRS2)    04932 Non-alcoholic fatty liver disease     122907240 (IRS2)    04931 Insulin resistance     122907240 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  122907240 NCBI-ProteinID:  XP_044106027 LinkDB All DBs Position 5:complement(164235814..164264613) Genome browser AA seq 1329 aa AA seqDB search MASPPLHGAPGPAGGDGPNLNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGDEAAAAA GGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYF AVAAENEQEQEGWYRALTDLVSEGRAGDAPPAAATAASCSASLPGALGGSAGAAAADDSY GLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMN IRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRS KSQSSGSSSTHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTA SEGDGGAAAGAGAAGARPVSVAGSPLSPGPVRAPLNRSHTLSGGCGARASKAAPAPAGGA LQHSRSMSMPVARSPPAATSPGSLSSSSGHGSGSYPPPPGAHPHLPHPLHQPAGQRPSSG SASASGSPSDPGFMSLDEYGSSPGDLRAFGGHRSNTPESIAETPPARDGGGGELYGYMTM DRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATF SGSSGRLCPTCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGVALLGG GSGSCKSDDYMPMSPTSVSAPKQILQPRAAVAAALPATGTTVPAPTPTVSRAFPASGGSY KTSSPAESSPEDSGYMRMWCGSKLSMENTDTKLLPNGDYLNMSPSDAGTSGTPPDFFSAA LHGSGEMLRGVPGYCYSSLPRSYKAPYTCNADNDQYVLMSSPVGRILEEERLEPPSSPGA APASSAFEAGGGHSQPPHPVVPSPSRPSGSSGGRPEGFLNQRARLVRPTRLSLEGLQTLP SMHEYPLPPEPKSPGEYINIDFGDAGARLSPPAPPLLASAASSSSLLSASSPASSLGSGT PGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTQSGDPVGSLDALLSPEASSPYPPLPPRPA APASSLQPQHPPPPPPGELYRLPQASACQGPSAASSSSSETGDNGDYTEMAFGVAATPPQ PIAAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRR RHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGGSGVLGGGDEHTMSPR QLQPPPPQQARPWVPGQPGGLVGGPGGSSSPMCRETSAGFQNGLNYIAIDVRDEPGLSPT PQQHPHPQPGDKSAWGRTRSLGGLISTVGGSGSSGVCGGPGPGALPSANTYASIDFLSHH LKEATVVKE NT seq 3990 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgctgcacggggcccccgggccggcgggcggcgacggccccaacctc aacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcagaag cacggccacaagcgcttcttcgtgctgcgcgggcccggcgacgaggcggcggcggcggcg ggcggggggccggcgccgcagccgccgcggctcgagtactacgagagcgagaagaagtgg cggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaacatcaac aagcgcgccgacgccaagcacaagtacctgatcgcgctctacaccaaggacgagtacttc gcggtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcaccgacctg gtcagcgagggccgcgccggcgacgcgcccccggccgccgccaccgccgcgtcctgcagc gcctccctgcccggcgccctgggcggctcggccggcgccgccgcggccgatgacagctac gggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtgaacctgaagccc aagggcctgggccagagcaagaacctgacgggcgtgtaccgcctgtgcctgtcggcgcgc accatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctgcagctcatgaac atccggcgctgcggccactcggacagcttcttcttcatcgaggtgggccgctcggccgtc acgggcccgggcgagctgtggatgcaggcggacgactcggtggtggcgcagaacatccac gagaccatcctggaggccatgaaggccctcaaggagctcttcgagttccggccgcgcagt aagagccagtcgtcgggctcgtcctccacgcaccccatcagcgtccccggcgcgcgccgc caccaccacctggtcaacctgcccccgagccagacgggcctggtgcgccgctcgcgcacg gacagcctggccgccaccccgccggccgccaagtgcagttcgtgccgggtgcgcacggcc agcgagggcgacggcggcgcggcggcgggcgcgggggcggcgggcgccaggcccgtgtcg gtggccgggagtcccctgagccccgggccggtgcgcgcgcccctgaaccgctcgcacacc ctgagcggcggctgcggggcccgcgcgagcaaggcggcgccggcgccggcagggggcgcc ctgcagcacagccggtccatgtccatgcccgtggcgcgctcgcccccggccgccaccagc cccggcagcctgtcgtccagcagcgggcacggctccggctcctacccgccgccccccggc gcgcacccgcacctgccgcaccccctgcaccagcccgccggccagcggccctccagcggc agcgcctcggcctcgggctcccccagcgaccccggcttcatgtccctggatgagtacggc tccagccccggcgacctgagagccttcggcggccacaggagcaacacgcccgagtccatc gccgagactcccccggcccgggacggcggcgggggcgagctgtacgggtacatgactatg gaccggcccctgagccactgcggccgcccctaccgcagagtgtcgggggacggggcccag gacctggaccgagggctgaggaagaggacttactccctaaccacgcctgcccggcagcgg ccggtgccgcagccctcctccgcgtccctggatgagtacaccctgatgcgggccaccttc tctggcagctccggccgcctctgcccgacctgccccgcgtcgtctcccaaagtggcctac cacccctatcccgaggactacggcgacatcgagatcgggtcccacaggagctccagcagt aacctgggtgccgacgatggctacatgcccatgacccctggcgtggccctcctgggtggg ggtagtggcagctgtaagagtgatgactacatgcccatgagccccactagcgtgtccgcc ccgaagcagatcctgcagcctcgggccgctgtcgccgcagccctgcctgccacgggaacc acggtgccggcgcccacccctacggtcagcagggcttttccggcaagcgggggcagctac aagacgagctctccagccgagagctcccccgaggacagtgggtacatgcgtatgtggtgt ggctccaagctgtccatggagaacaccgacaccaagctgctccccaacggggactacctc aatatgtcccccagcgacgcgggtacctcgggaacccctcccgacttcttctcagccgcc ttgcatggcagtggggagatgctcaggggagtccctggctactgctatagctccctgccc cgctcctacaaggctccttacacgtgcaatgcggacaacgaccagtacgtgctcatgagc tcccccgtggggcgcatcctggaagaggagaggctcgaacccccatccagcccgggggct gcgccagccagcagcgccttcgaggcaggaggtggccacagccagcctcctcacccagta gtgccttcgcccagcaggccgagtggcagcagcgggggtcgcccagagggcttcctgaac cagcgcgcccggttagtgcggcccacacgcctgtccctggaggggctgcagaccctgccc agcatgcacgagtaccctctgccgccggagcccaagagccccggcgagtacatcaacatt gactttggcgacgccggagctcgcctgtctccgcctgcgcccccgctgctggcttccgcg gcctcctcgtcctcactgctgtccgccagcagcccggcctcctccctgggctccggcacc ccaggcacgagcagcgacagcaggcagcgctccccgctctccgactacatgaacctcgac ttcagctcgcccaagtcgcccaagccgggcacccagagcggggaccccgtgggctccctg gatgccctgctgtcccccgaggcctcgtccccctacccgccgctgcccccgcgccccgct gcccccgcctcctcgctgcagccgcagcatcccccaccgccccccccaggggagctgtac cgcctgccacaggcgtccgcttgccagggccccagcgctgcctcctcctcgtcctcggag accggggacaacggtgactacaccgagatggcctttggcgtggctgccaccccgccacaa cccatcgcggcccccccgaagccggaaggtgcccgtgttaccagcccaacgtccggctta aagaggctgagtctcatggatcaggtgtcgggtgtcgaggccttcctgcaggctagccag cccccagaccctcaccggggagccaaggtcatccgcgcagacccacaggggggccgccgg cgccacagttccgagaccttctcctcgaccaccactgtgacccccgtgtccccgtccttc gcccataaccctaagcgccacaactcggcctccgtggaaaatgtctctctcaggaaaagc agtgaagggggcggcagtggcgtcctgggtgggggggacgagcacaccatgtcccctcgc cagctgcagccgccgcccccccagcaggcacgcccatgggtcccgggtcagccgggtggc ttggtgggcggccccgggggcagcagctctcccatgtgcagggagacctctgccggcttc cagaatggcctcaactacatcgccattgacgtgagggacgagcctgggctgtcaccgacc ccacagcagcacccgcatccgcagcccggagacaagagtgcctggggccggacccgcagc ctcgggggtctcatcagcactgtggggggcagcggcagcagtggggtttgcggggggccg ggccctggcgccctcccctccgccaacacctatgccagcattgacttcttgtcccatcac ctgaaggaggccaccgttgtgaaagagtga

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