| Entry |
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| Symbol |
ARHGEF1
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| Name |
(RefSeq) rho guanine nucleotide exchange factor 1 isoform X1
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| KO |
| K12330 | Rho guanine nucleotide exchange factor 1 |
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| Organism |
nvs Neogale vison (American mink)
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| Pathway |
| nvs04270 | Vascular smooth muscle contraction |
| nvs04810 | Regulation of actin cytoskeleton |
| nvs04928 | Parathyroid hormone synthesis, secretion and action |
| nvs05163 | Human cytomegalovirus infection |
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| Brite |
KEGG Orthology (KO) [BR:nvs00001]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
122912005 (ARHGEF1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
122912005 (ARHGEF1)
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
122912005 (ARHGEF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
122912005 (ARHGEF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122912005 (ARHGEF1)
05205 Proteoglycans in cancer
122912005 (ARHGEF1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
122912005 (ARHGEF1)
09171 Infectious disease: bacterial
05135 Yersinia infection
122912005 (ARHGEF1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122912005 (ARHGEF1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:nvs04131]
122912005 (ARHGEF1)
Membrane trafficking [BR:nvs04131]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
122912005 (ARHGEF1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
7:55501588..55519645
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| AA seq |
978 aa
MEAEDIARRLAPGPLRPGLVPVSIIGAEDEDFENELETNAEEHNSQFQSLEQVKRRPAHL
MAFLQHVALQFEPGPLLCCLHADILASLGPKEAKKAFLDFYHSFLDKTAVLRVPVPPTVS
FELDRTRPDLLSEDVQRHFVQDVVQNQQATVSRLLEDFRSKRLMGMTPWEHDLTQLEAWV
GRDRASFEARERHLAERLLTHLEEMQHTISPDEEKSAAVVSAISLYMRHLGVRTKSGDKK
SGRNFFRKKMMGNRRSDEPTKTKKGLSILLDAARWNRGEPQAPDFRHLKVEADAEKPGLT
ERRGGLGVPSRDRNVGAPGQDVPGVSPHPLSGDSPDREAGVDAPPELGDPPLQGPASLEP
LAPPESTEEGADTERRWKRLSGRLGRSESLRVSDRRRPSRGSLGAKGRGGGRSRSDVDMD
PSSATAVLGPTRRATPEPGDEGDPARSGLEIEPEEPPGWRELVPLGTLHSLPKSQVKRQE
VISELLVTEAAHVRMLRVLHDLFYQPMAEGGFFSLEELQNIFPSLDELIEVHSLFLDRLM
KLRQDSGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAF
VQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPAEREKVELAAECCREIL
HHVNQAVRDMEDLLRLKDYQKRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVT
KDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAITREVA
TDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCSLITETAGSLKVPAPASRSKSRPSPSS
TREPLLSNSENGNGGGREMPPADGRTERILSMLLPYSRPGPEGQLSAKALEKVLSLKQLL
FPSEEDSGAGPPREGDGVPGGASQSQDRTQDQTQEIREKLLSLEETMKQLEEVEEEFCRL
RLLLSQLGENAAPQPGCT |
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| NT seq |
2937 nt +upstreamnt +downstreamnt
atggaggcagaggacatcgcccgcaggctggccccaggaccattgcggcctggcctggtg
ccagtcagcatcattggggctgaggatgaggattttgagaatgagctggagacgaacgca
gaggagcacaacagccagttccagagcctggagcaggtgaagcggcggcctgcccacctc
atggcctttctgcagcacgtggccttgcagtttgaaccgggacccctgctctgctgcctg
cacgcagacatactggcttccctgggtcccaaagaggccaaaaaggccttccttgacttc
taccatagcttcctggacaagactgcggttttgcgagtgccggtccctcccactgtctcc
tttgaactcgaccgcacgcgacccgacctcctctctgaggatgtccagcggcacttcgtg
caggacgtggtgcagaaccagcaggccactgtcagccggctgctggaggacttccgctcc
aagcggctcatgggcatgacaccctgggagcacgacctgacccagctggaggcctgggtt
gggcgggaccgtgccagctttgaggcccgggagcggcacctggccgagcggctactgacc
cacctggaggagatgcaacacaccatctctcccgatgaggaaaagagtgccgctgtggtc
agcgccatcagcctgtacatgcgccaccttggggtgcggaccaagagcggggacaagaag
tcggggaggaatttcttccgaaaaaagatgatggggaatcggcggtcagatgagccaacc
aagaccaagaaaggcctgagcatcttactggatgccgcccgctggaaccggggcgagcct
caggcccccgatttccgacacctcaaagtcgaggctgatgctgagaagccaggccttacg
gaaaggaggggaggcctaggagtgccctcccgggaccggaacgtcggggctcctgggcag
gacgtccctggagtttctccacaccctctgtctggagacagccccgaccgggaagcaggt
gttgatgccccaccagagctgggggacccaccactgcagggcccggccagcctggagccc
ctggcgcccccagagagcactgaggagggtgctgacacagagagaagatggaagaggcta
tcggggcgtctggggcgctcggagagcctgcgggtgagtgaccgccgccggccttcccgg
ggcagcctcggggctaagggccggggtgggggccgctcccggagtgacgtggacatggac
cccagctctgccacagccgtgcttggccctacccgacgagccacccctgagcctggagac
gaaggggacccagcacggtcaggactagaaatagaaccagaagagccccctggctggcgg
gagcttgtccccctcggcaccctgcacagcctgcccaagagccaggtgaagcggcaggag
gtcatcagtgagctgctggtgactgaggccgcccatgtgcgcatgctccgggtgctgcat
gaccttttctaccagcccatggcagaagggggcttcttctccctggaggagctccagaac
atcttccccagcctggacgagctcatcgaggtgcattccctgtttctcgatcgactgatg
aagctcaggcaggatagtggctacctcattgaggagatcggagacgtgctgctggctcgg
tttgatggtgccgaaggcagctggttccagaaaatctcctcccgcttctgcagccgccag
tcatttgccttagagcagctcaaagccaagcagcgcaaggagcctcggttctgtgccttt
gtgcaggaggctgagagccgcccccggtgtcgccgcctgcagctgaaggatatgatcccc
acggagatgcagcgtctgaccaagtatccgctgctcctccagagcatcgggcagaacaca
gaagagccggcggaacgagagaaagtggaactggcagctgagtgctgccgagaaattctg
caccacgtcaatcaggctgtgcgcgacatggaggacttgctgcgactcaaggattatcag
aagcgcctggacttgtcccacctacgtcagagcagcgaccccatgctgagcgagttcaag
aacctggatatcaccaagaagaagctggtgcatgagggcccgctgacatggcgggtgacg
aaggacaaggctgtggaagtccatgtgctgctgctggatgacttgctgctgctgctccag
cgccaggacgagcggctactgctcaagtcccacagtcggacgctgacacccacacccgac
ggcaagaccatgctgcggccggtgctgcggctcacgtccgccatcacccgcgaggtggcc
accgatcacaaagccttttatgtcctttttacgtgggaccaggaggcacagatctatgaa
ctggtggcccagaccgtgtcggaacggaagaactggtgttccctcatcaccgagactgct
ggatccttgaaggtccccgctcccgcctctcgctccaaatcccggcccagcccgagcagc
acccgagagcccctgctcagcaactctgagaacggcaacggcggtggccgagagatgccc
ccagcggatggccggacagaaaggatccttagcatgctcctgccctactccagacccggc
cccgagggccagctctctgccaaggccctggagaaagtgctgtccctgaagcagctcctg
tttccctcggaggaagacagcggggcggggcctccccgtgaaggggatggggtcccaggg
ggcgcctcccagagccaggaccggacccaggaccagacccaggagattcgggagaagctg
ctcagcctggaggagaccatgaaacagctggaggaggtggaggaggaattttgtcgcctg
cgactcctcctatctcagctcggggagaacgctgccccccagcctggctgtacctga |
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