Neogale vison (American mink): 122916145
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Entry
122916145 CDS
T08764
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
nvs
Neogale vison (American mink)
Pathway
nvs04120
Ubiquitin mediated proteolysis
nvs04144
Endocytosis
nvs04330
Notch signaling pathway
nvs04668
TNF signaling pathway
nvs04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
nvs00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
122916145 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
122916145 (ITCH)
04668 TNF signaling pathway
122916145 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122916145 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
122916145 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
nvs04131
]
122916145 (ITCH)
04121 Ubiquitin system [BR:
nvs04121
]
122916145 (ITCH)
Enzymes [BR:
nvs01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
122916145 (ITCH)
Membrane trafficking [BR:
nvs04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
122916145 (ITCH)
Ubiquitin system [BR:
nvs04121
]
Ubiquitin ligases (E3)
HECT type E3
122916145 (ITCH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
122916145
NCBI-ProteinID:
XP_044119135
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All DBs
Position
8:complement(23950987..24085904)
Genome browser
AA seq
864 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIFETLKSNNMKLEEVVVTL
QLVGDKEPTEIGDLSVCLDGLQLDSEVVTNGETTCSENVEGASQSDDGSRPKDETRTNTN
GSDEPEDAGAGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSE
SDGSSTGSLPPTNINSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRVDQH
GRVYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQ
WQLQRSQLQGAMQQFNQRFIYGNQDLFTTSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNH
NTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNG
PQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWV
IFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFR
FIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEEC
GLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE
GFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEI
DNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPP
YKSYEQLKEKLLFAIEETEGFGQE
NT seq
2595 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttatcgtcacccctgtgagtaaattacat
tttcgtgtatggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctttgaaaccttaaagtcaaacaacatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccgacagaaataggagacttgtcagtttgtcttgatggg
ctgcagttagattctgaagttgttaccaatggtgaaactacatgttcagaaaatgttgaa
ggtgcttcacagagtgatgatggctccagacccaaggatgaaacaagaacaaacacaaat
ggatcagatgagcctgaggatgcaggggctggtgaaaataggaaggtcaatgggaataat
tctccatcactctcaaatggtggttttaaaccttctaggcctccaagaccttcacgacca
cctccacctaccccacgtagaccagcatctgtcaatggttccccatctgccacttctgaa
agtgatggatccagtacaggctctctgccaccaacaaatataaattcaaatacatctgaa
ggagcaacatctggattaataattcctctgactatatctggaggctcaggccctcggcca
ttaaatcctgtacctcaggctcccctaccacctggttgggagcagagagtggaccagcat
gggcgagtttactatgtagatcatattgaaaaaagaacaacatgggatagaccagaacct
ctacctcctggctgggaacgtcgggttgataacatgggacgaatttactatgttgaccat
ttcacaagaacaacaacgtggcagaggccaacattggaatccgtccggaactatgaacag
tggcagctccaacgtagtcagctgcaaggagcaatgcagcagtttaaccagagatttatt
tatgggaatcaagatttgtttactacatcacaaaataaagaatttgatccccttggtccc
ctgccacctggatgggagaagagaacagacagcaatggtagagtatactttgtcaaccac
aacactcgtatcacacagtgggaagatcccagaagtcaaggtcaattaaatgaaaagccc
ttgcctgaaggctgggaaatgagattcacagtcgatggaattccatattttgtggaccac
aatagaagaacaaccacctatattgatccccgcactggaaaatctgccctagacaatgga
ccacagatagcctatgtacgggatttcaaggcaaaagttcagtatttccggttctggtgt
cagcaactggctatgccacagcacataaagattacagtgacaagaaagaccttgtttgaa
gattcctttcagcagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtg
atttttccaggagaagaaggtttagattatggaggtgtagcaagagagtggttctttctt
ttgtcacacgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataac
tactgcttgcagataaatcctgcttcttacatcaatccagatcacctgaaatactttcgt
tttattggcaggtttattgccatggctctcttccatgggaagttcatagacacaggtttt
tctttgccattctataaacgtatattgaacaaaccagttggactcaaggatttagaatct
attgatccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgt
ggtttggaaatgtacttctctgtcgataaagaaattttaggtgaaatcaagagtcatgat
ttgaaacctaatggtggcaatattcttgtgacagaagaaaataaagaggaatatatcaga
atggtagctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgag
ggctttaatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagag
gtccttttatgtggaatgcaagagattgacttgaatgactggcaaagacatgccatctac
cgccattacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaatt
gataatgagaagagaatgagacttctgcagtttgttactggaacctgccgattgccagtt
ggaggatttgctgacctcatggggagtaatggaccacaaaaattctgcattgaaaaagtt
gggaaagaaaattggttacccagaagtcatacatgttttaatcgcctggacctgccaccc
tacaagagctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaagga
tttggacaagagtaa
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