Ornithorhynchus anatinus (platypus): 100074148
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Entry
100074148 CDS
T01045
Symbol
MTHFD1L
Name
(RefSeq) monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform X1
KO
K13402
monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:
6.3.4.3
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00670
One carbon pool by folate
oaa01100
Metabolic pathways
oaa01240
Biosynthesis of cofactors
Module
oaa_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100074148 (MTHFD1L)
Enzymes [BR:
oaa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
100074148 (MTHFD1L)
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Ortholog
Paralog
GFIT
Motif
Pfam:
FTHFS
THF_DHG_CYH_C
THF_DHG_CYH
Ddi2_HDD
DUF2325
Motif
Other DBs
NCBI-GeneID:
100074148
NCBI-ProteinID:
XP_028913941
Ensembl:
ENSOANG00000021726
UniProt:
K7EBW2
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Position
2:complement(76850445..77020272)
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AA seq
942 aa
AA seq
DB search
MRPRQALVSLQLLRAAPRRALGLLGRRPPAARPGRPETVRDIIQNSKEVLTVLRQGNPTF
KPVLAIVQVGDDPFMQEISQNMAEETGLNITHICLPSESSEDEIIDEVLKLNGDVKVHGL
ALQLSSGSYSNKILNAVKPEKDVDGVTDVNLGKLVRGDAHECFVSPTARAVIELLEKSDL
AIDGKKVLVLGAHGSLEAAVQCLFQRRGAMMMSCQWKTQQLQKKLQEADIVVIGSPKPEE
IPISWIRPGITIINCSRDFPTEKHDFSQSNLQYSDLVVEEDVSTLAAALRIQNVVNSGRR
WLREQQYRRWKLHCLKLQPLSPVPSDIEISRGQSPKAVDVLAKEIGLLADEIEIYGQSKA
KVRLSLLERLKDQADGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLNVNSFACLRQPS
QGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDTRILHESTQTDK
ALYNRLVPLVNGVREFSEIQLSRLKRLGINKTDPGSLTDDEMSKFARLDIDPSTITWQRV
LDTNDRFLRKITIGQANTEKGFFRQAQFDIAVASEIMAVLALTNSLADMKERLGRMVVAS
DKSGQPVTAEDLGVTGALAVLMKDAIKPTLMQTLEGTPVFVHAGPFANIAHGNSSVLADK
IALKLVGEEGFVVTEAGFGADIGMEKFFNIKCRTSGLIPSAVVLVATVRALKMHGGGPNV
TAGVPLKKEYTEENLQLVADGCCNLQKQIQIAQLFGVPVVVALNVFKTDTNAEIDLVCEL
AKRSGAFDAVPCHHWSVGGKGAVDLARAVREAANKKNRFRFLYDLELPIVDKIRTIAQTV
YGAQDIELSPEAKAKVDRYTQQGFGKLPICMAKTHLSLSHQPERKGVPTGFILPISDVRA
SIGAGFIYPLVGTMSTMPGLPTRPCFYDIDLDTDTEQVKGLF
NT seq
2829 nt
NT seq
+upstream
nt +downstream
nt
atgcggccgaggcaggccttggtgtccctccagctgctccgggccgctccccgccgggcc
ctcggcctgttggggcggcggcccccggcggctcggcccggccgccccgaaaccgtcaga
gacattatccagaattcaaaagaagttctgactgtattgcggcaaggaaatcctaccttt
aagccagtacttgctattgtccaggtaggagatgatccattcatgcaggaaataagccag
aacatggcagaggagactggtttgaatattactcacatttgccttccttcagagagcagt
gaagatgagattattgatgaagtcttgaagctcaatggtgatgtcaaagttcatggcctt
gctctccaactctccagtggctcatatagcaataaaatactgaatgctgtaaaacctgag
aaagatgtggatggggtgacagatgtaaatctgggaaaattggttcgtggtgatgctcat
gaatgcttcgtgtcacctactgccagagctgtcattgaacttcttgaaaaatcagattta
gctatagatggaaagaaggtgttggtccttggggctcatggatcgctagaagctgccgtg
cagtgcctgtttcagagaaggggtgccatgatgatgagctgccaatggaaaacacaacaa
ctgcagaagaagctgcaggaagctgatattgtggtcattggctctcccaagcctgaggaa
atccccatcagttggatcagaccaggaattactattatcaattgttcccgtgattttcca
acagagaaacatgatttcagccagtcaaatttgcagtacagtgatttggtcgttgaagag
gacgttagtacacttgcagcagctctgcggattcagaatgttgtaaatagtggtagaaga
tggcttcgtgaacagcagtatagaaggtggaagctccattgtttaaaactacagcctcta
tcaccagtacccagtgatattgagatttccagaggacaaagtccaaaagctgttgatgtg
cttgccaaggagataggattgcttgcagatgaaatcgaaatctacggtcagagcaaagcc
aaagtacgtttgtccctgttagaaaggttaaaggatcaagcagatggaaaatacgttttg
gttgctgggattactcccacgccccttggagaagggaaaagcacagtcacaattggactg
gttcaagcactgacagcacacctgaatgttaattcctttgcttgtctgaggcaaccttca
caaggacccacatttggagttaaaggtggtgctgcaggaggtggctatgctcaagttatc
ccaatggaggagttcaatcttcacttgactggagacattcacgccattactgctgcaaat
aatttgctggctgctgctattgacaccaggattttgcatgaaagcactcagacagataaa
gccctatataatcggttggttccattagtgaatggtgtgagggaattttcagaaattcag
ctttctcgattaaaaaggctgggtattaacaagacggatccaggctcactcactgacgat
gagatgagtaaatttgctcgacttgacattgacccatccaccataacttggcaaagagtg
ttggacacaaatgaccgatttttgcgaaaaataacaattgggcaggcaaacacagagaag
ggattctttcgtcaggcccaatttgacattgctgtggcaagtgagatcatggccgtgttg
gcgttgactaacagcctcgcagatatgaaggagcgacttggaagaatggtggtggctagt
gataaaagtggacagcctgtaaccgcggaagatttaggagtaactggagctttggcagtt
ttgatgaaagatgcaattaaaccaactcttatgcagacattagaggggacaccagttttt
gtacatgcaggaccctttgctaacattgcacatggcaattcttctgtgctggcagacaag
attgccctgaaattggttggagaggaaggttttgtggtaactgaagctggttttggtgct
gatattgggatggagaaattcttcaacatcaagtgcagaacttctggactcattcccagt
gctgttgtgctggttgcaacagtgcgggctttgaagatgcatggaggcgggccaaatgtc
actgctggtgtcccgcttaagaaagaatatacagaggagaatcttcagctggtagccgat
ggttgctgtaatctacagaagcagattcagattgctcagctatttggagttccagttgtg
gttgccctaaacgtcttcaagaccgacacaaatgccgagattgatttggtgtgtgagctt
gcaaaacggtctggagctttcgatgcagtgccctgtcatcactggtcagtgggaggtaaa
ggggcagtggacttggctcgtgctgtaagagaagctgccaataagaaaaaccgcttccga
ttcctatatgatttggagctccccattgttgacaaaataaggactattgcccagacagtc
tatggagcccaggatatagaactatcccctgaagcaaaagcaaaagtagaccggtacacc
caacagggctttggaaagttgccaatttgtatggcaaaaacccacctgtctctctctcac
caacctgagaggaaaggagtacccactggcttcattctcccaattagcgatgtccgtgcc
agcattggggcaggattcatttaccctctggtgggaacgatgagcaccatgccaggattg
cctacccgcccatgcttctacgatatagacctggacacggacaccgagcaagttaaaggc
ttgttctga
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