Ornithorhynchus anatinus (platypus): 100076789
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Entry
100076789 CDS
T01045
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa01522
Endocrine resistance
oaa04012
ErbB signaling pathway
oaa04062
Chemokine signaling pathway
oaa04148
Efferocytosis
oaa04151
PI3K-Akt signaling pathway
oaa04360
Axon guidance
oaa04370
VEGF signaling pathway
oaa04510
Focal adhesion
oaa04670
Leukocyte transendothelial migration
oaa04810
Regulation of actin cytoskeleton
oaa04935
Growth hormone synthesis, secretion and action
oaa05100
Bacterial invasion of epithelial cells
oaa05135
Yersinia infection
oaa05146
Amoebiasis
oaa05163
Human cytomegalovirus infection
oaa05165
Human papillomavirus infection
oaa05170
Human immunodeficiency virus 1 infection
oaa05200
Pathways in cancer
oaa05202
Transcriptional misregulation in cancer
oaa05205
Proteoglycans in cancer
oaa05208
Chemical carcinogenesis - reactive oxygen species
oaa05222
Small cell lung cancer
oaa05417
Lipid and atherosclerosis
oaa05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100076789 (PTK2)
04370 VEGF signaling pathway
100076789 (PTK2)
04151 PI3K-Akt signaling pathway
100076789 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100076789 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100076789 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100076789 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
100076789 (PTK2)
04062 Chemokine signaling pathway
100076789 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
100076789 (PTK2)
09158 Development and regeneration
04360 Axon guidance
100076789 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100076789 (PTK2)
05202 Transcriptional misregulation in cancer
100076789 (PTK2)
05205 Proteoglycans in cancer
100076789 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
100076789 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
100076789 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100076789 (PTK2)
05163 Human cytomegalovirus infection
100076789 (PTK2)
05165 Human papillomavirus infection
100076789 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
100076789 (PTK2)
05100 Bacterial invasion of epithelial cells
100076789 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
100076789 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100076789 (PTK2)
05418 Fluid shear stress and atherosclerosis
100076789 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100076789 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oaa01001
]
100076789 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
oaa01009
]
100076789 (PTK2)
Enzymes [BR:
oaa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100076789 (PTK2)
Protein kinases [BR:
oaa01001
]
Non-receptor tyrosine kinases
FAK family
100076789 (PTK2)
Protein phosphatases and associated proteins [BR:
oaa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
100076789 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
GIT1_C
Motif
Other DBs
NCBI-GeneID:
100076789
NCBI-ProteinID:
XP_028919977
Ensembl:
ENSOANG00000007126
LinkDB
All DBs
Position
4:378942..522175
Genome browser
AA seq
1142 aa
AA seq
DB search
MLWDRAGRRASKPAGATWMEKRGCSPFPMCWAKEYDRYLASSKTMAAAYLDPNLNHTPSS
GAKTHLSAGMERSPGAMERVLKVFHYFENNSEPTSWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSSVRENYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKNDYMLEVADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLRRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRYDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGSNPTHLADFNQVQTIQYSNSEDKDRKGTL
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL
ANNEKQGARTHTVSVSGVSHCQHKVKKARRFLPLVFCSHEPPPPDEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRDRIDLGRCIGEGQFGDVHQGVYTTPENPAMAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
FSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSSDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGIKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKLQQEERMRMES
RRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQANHYQVSGYPGPHGVPA
LAGSIYPGPTPLLDQADSWNHRPQEIAMWQPNLEESAAMDMRGLGSMLPPTQLMEERLIR
QQQEMEEDQRWLEKEERSLKPDVRLSRGSMDREDGSLPGGPTGNQHIYQPVGKPDPAAPP
KKPPRPGAPSHLGSLASLSSPVDSYNEGVKPWRLQPQEISPPPTANLDRSNDRVYENVTG
LVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLAAVDETMPVLPASTLREIEMAQKLL
NSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMIGQAR
PH
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atgttgtgggaccgggcaggccggcgggcctcgaaaccggcaggtgcaacctggatggag
aaaagaggctgcagccccttccccatgtgttgggccaaagaatatgaccgatacctagca
tcaagcaaaaccatggcagctgcatacctcgatcccaacttgaaccacactccgagttcc
ggcgcaaagactcatctaagtgcaggaatggagcgttcccccggggccatggagcgagtg
ttaaaagtctttcattattttgaaaataacagcgaaccgacgtcatgggccagcatcatc
cgacatggagacgccactgatgtccggggcataattcagaagatcgtggacagtcacaag
gtcaaacatgtggcctgttatggattccgccttagccacctgcgttcggaggaggttcac
tggctccatttggatatgggcgtttccagcgtgagagagaactatgaactagcccaccct
ccagaggaatggaaatatgaactgagaattcgctatttgccaaaaggatttctgaaccag
tttactgaggataaaccaactttgaatttcttctatcagcaggtgaaaaatgactacatg
ttggaggtagcagaccaagtggaccaagaaatcgctttgaaactaggttgcctagaaatt
cgacggtcctactgggagatgaggggcaatgctctggagaagaagtccaactacgaagtg
ctagagaaagatgttggtttaagaagattttttccaaagagtttactggactctgtcaag
gccaaaacactgcgaaagctgatccagcagacatttcggcagtttgccaaccttaataga
gaagaaagtattctgaaattttttgagattctctctccggtgtacagatacgataaagaa
tgcttcaagtgtgctctcggttcaagctggatcatatcagtggagctggcaattggtcca
gaagaaggaatcagttatctcacggataagggctctaatcctacacacctggcggacttc
aatcaagtgcagacgattcagtactccaacagtgaagacaaagacagaaaaggaacgctg
caactcaaaatagcaggggcacctgagcctctgacagtgacagccccatccttaaccatt
gcggagaacatggctgatctgatcgatggatattgccggttggtgaacggagcctcccag
tccttcatcatcagaccccagaaagaaggtgaaagggctttaccatcaataccaaagctg
gccaacaatgaaaagcaaggagcaaggacacatacagtctctgtgtcaggagtcagtcac
tgtcagcataaagtaaagaaagctagacgctttctcccgttggtcttctgttcccacgag
ccgccacctccggatgaaattagtggggacgaaacagatgactatgcggagattatagat
gaagaagatacttacaccatgccatcaaaaagctatggaatagatgaagccagggattat
gagattcagcgggacagaatagatcttggacggtgtattggagaaggccagtttggagat
gtgcatcaaggcgtttacacaactccggagaatccagccatggcagttgcaattaaaaca
tgtaaaaactgtacctccgacagtgtgagagaaaaattcctccaagaagccctaacaatg
cgccagtttgaccacccgcatatcgtgaagctcattggcgttataactgagaacccggtc
tggatcatcatggagctgtgcacccttggggagctaaggtcatttttacaagtgaggaag
ttcagtttggacttggcttctttgattctctatgcctaccagctcagtacagctcttgca
tatctggagagcaagaggtttgttcatcgggacattgctgctaggaacgtattggtgtcc
tcctctgactgtgtgaaattaggagactttggtttgtcacgatacatggaagacagtacg
tactacaaagcctccaaagggaaattaccgataaagtggatggctccagagtccatcaat
ttccggcgcttcacctcagccagcgacgtttggatgtttggtgtgtgcatgtgggaaatt
ttgatgcacggcatcaagcctttccaaggagtgaagaacaatgacgtgattggccgaatt
gagaatggggaacggctcccaatgcctccgaactgccctcccaccctctacagcctaatg
acgaaatgttgggcctacgatcctagcaggaggcctcggtttacggagctcaaagcccag
ctcagtaccatcctggaggaagaaaagctgcagcaggaagagcggatgaggatggaatcg
cggagacaagtcaccgtgtcctgggattcgggaggctccgatgaagctccgcccaagccc
agcagacctggttaccccagtccaagatccagtgaagggttttatcctagtccccagcac
atggtccaagccaatcattaccaggtctctggttaccctgggcctcacggggtgcccgcc
ttggctggcagcatttacccaggaccaacacctctgttggaccaagcagattcgtggaac
caccggcctcaggagatagcaatgtggcaaccgaacctggaggaatcggcggccatggac
atgcggggcctagggtccatgctgccccccacacagctgatggaggagaggttgatccgg
cagcagcaagagatggaggaagatcaacgctggcttgagaaggaagagcgatccttgaag
cctgatgtgaggctttcacgaggcagcatggaccgagaggacggaagcctgccgggcggc
ccgacagggaatcaacatatataccagcctgtgggtaaaccagaccccgcagccccgcct
aagaaacctcctcgcccgggagcccctagtcacctgggaagcctcgccagcctcagcagc
cccgtggacagctacaacgaaggagtgaagccatggaggctccagccccaggaaatcagc
ccccctcctaccgcaaatttggaccgttccaacgacagggtgtacgagaacgtgacgggc
ctggtcaaagcggtgatagaaatgtctagtaagatccagccagcccctccagaggaatat
gtgccaatggtgaaggaagttggcttggccctgagaacgctgctggcagcggtggacgag
accatgcccgtcctcccagcgagcactctccgagagatcgagatggcgcagaagctgctt
aactcagatttgggggagctgatcaacaagatgaaacttgcccaacagtacgtcatgacc
agcctccagcaggaatacaaaaaacaaatgctcacagctgctcacgcgctggccgtggat
gccaaaaacctgctcgatgtcattgatcaagcccgcttgaaaatgattgggcaggccagg
ccccattaa
DBGET
integrated database retrieval system
