Ornithorhynchus anatinus (platypus): 100076923
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Entry
100076923 CDS
T01045
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa00061
Fatty acid biosynthesis
oaa00620
Pyruvate metabolism
oaa00640
Propanoate metabolism
oaa01100
Metabolic pathways
oaa04152
AMPK signaling pathway
oaa04910
Insulin signaling pathway
oaa04920
Adipocytokine signaling pathway
oaa04922
Glucagon signaling pathway
oaa04931
Insulin resistance
oaa04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100076923 (ACACB)
00640 Propanoate metabolism
100076923 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100076923 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100076923 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100076923 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100076923 (ACACB)
04922 Glucagon signaling pathway
100076923 (ACACB)
04920 Adipocytokine signaling pathway
100076923 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100076923 (ACACB)
04931 Insulin resistance
100076923 (ACACB)
Enzymes [BR:
oaa01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100076923 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100076923 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100076923 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100076923
NCBI-ProteinID:
XP_001508230
LinkDB
All DBs
Position
21:17981152..18107213
Genome browser
AA seq
2446 aa
AA seq
DB search
MLLILTFLLLTFAWFVSSAMADLKPPTASEPEVPPREPSPDPVDKGDPETAQAQQNSEVN
EPPSRPNQAMPDPSRASQNPGHLATRPPHWRPSNDPPVLDATSATADHRANGLEGSPTPD
LLSPSGSQAKRVRPLSKEDQKQARIRKQLMTKFILGSFDDNSSDDEAVAGAFKASSRRSS
RSSFGSSSFETSSLLGLTRSESTPIMRPSMSGLHLVKRGREQKKLEQQRDFTVASPAEFV
TRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYI
KMADHYVPVPGGPNNNNYANVELIVDISKRIPVQAVWAGWGHASENPKLPELLHKNGIAF
LGPPSEAMWALGDKVASTIVAQTLQIPTLPWSGSGLSVDWTASDLQQMKRISVPQEVYVR
GCVRDVDEGLEAAEKIGFPVMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPVFV
MKLAQHARHLEVQILADQYGSAVSLFGRDCSIQRRHQKIIEEAPATVAPPAVFEYMEQCA
VRLAKTVGYVSAGTVEYLYSDDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGV
PLNRLKDIRILYGELPWGILPISFENPTNPPVPRGHVIAARITSENPDEGFKPSSGTVQE
LNFRSSKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFR
TTVEYLINLLETESFQGNDIDTGWLDYLIAERVQAEKPDIMLGVVCGALNVADALFRTCM
TDFLHSLERGQVLPAASLLNIVDVELIYDGVKYTLKVARQSLTMFVLIMNDGHIEIDAHR
LNDGGLLLSYDGNSYTTYMKEEIDSYRITIGNKTCVFEKENDPTVLRSPSAGKLLQYTVE
DGGHVVAGNSFAEIEVMKMIMTLNVQESGRVYYVKRPGAVLEAGCSVARLELDDPSKVHP
AEPFTGNLPAQQTLPIMGEKLHQVFHNVLENLTNVMNGYCLPEPIFSAKIKEWVSKLLVT
LRDPSLPLLELQEIMTSVSGRIPPSVEKSVRKVMAQYASNITSVLCQFPSQQIANVLDCH
AATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMTAVVLELLRKYLQVEHNFQQAHYDK
CVINLREQFKPDMSQVLDCIFSHAQVAKKNLLVTMLIDELCGPDPTLTDELLAILNELTQ
LSKTEHSKVALRARQVLIASHLPSYELRHNQVESIFLSAIDLYGHQFCPDNLKKLILSET
TIFDVLPMFFYHVNPVVCMASLEVYVRRGYIAYELNSLQHRKLPDGTCVVEFQFMLPSSH
PNRMHIPISVTNPDLVRHSTELFMDSGFSPLCQRMGAMVAFTKFEDFTRNFDDVISCFAN
LPKDCPLFHEARSTLYCEEDSKNVREEPIHILNVAIKCADHLEDEALVPVFRTFVQSKKN
ILVEYGLRRITFLIAQQREFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLT
AVPCANHKMHLYLGAARVEEGAEVTDYRFFIRAIIRHSDLITKEASFEYLQNEGERLLLE
AMDELEVAFSNTTVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAE
VKINIRLTTTGTAIPIRLFLTNESGYYLDISLYKEVTDAGTGNIMFNSFGDKEGAQHGML
INTPYMTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSSDKYPKDVLTCTELVLD
SQGQLVQMNRLPGGNEVGMVAFKMKMKTREYPEGREVIVISNDITFKIGSFGQGEDLLFL
RASELARAQGIPRIYLSANSGARIGLAEEIRDMFRVAWVDPEDPYKGFKYLYLTPQDYTR
ISSLNSVHCEHVEEGGESRYVITDIIGKDDGLGVENLRGSGTIAGESSLAYEEIVTVSMV
TCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHFNGI
SHITVPDDFEGVYTILEWLSYMPKDNRSPVPIITPMDPIDREIEFVPSKAPYDPRWMLAG
RPHPTVKGTWQSGFFDQSSFKEIMEPWAQTVVTGRARLGGIPVGVIAVETRSVELVIPAD
PANLDSEAKIIQQAGQVWFPDSAFKTAQAIKDFDRERLPLLIFANWRGFSGGMKDMYDQV
MKFGAYIVDGLRQYKQPVLIYIPPYAELRGGSWVVIDPTINPFCMELYADKESRGGVLEP
EGTVEIKFRKKDLIKAMRRIDTVYGKLVEQLGSPELSEKDRRDLERKVKGREELLLPIYH
QVAVQFADLHDTPGRMQEKGVITDILEWKNSRTFLYWRLRRLLLEGVVKNEILLANSELS
HVHIQSMLRRWFLETEGTVKGYLWDNNQVVAAWLEKHLQEEDGSRSAIRENIKYLKRDFA
LKNIRGLVQEHPEVVMDCIVHMTQHISPAERAQVAHLLATLENPST
NT seq
7341 nt
NT seq
+upstream
nt +downstream
nt
atgctcttgatcttgactttcctactcctgacttttgcgtggtttgtgtcgagcgccatg
gccgacttgaagcctcctactgcaagtgagcccgaagtcccaccccgagagccttctccg
gaccccgtggacaaaggggacccggaaacggctcaagctcagcaaaactcggaggtgaat
gagcccccttcgaggcccaaccaagccatgccagaccccagccgggcctcccaaaacccc
gggcatctggcgactcgtccgccgcactggagaccctccaacgaccctccggtcctggat
gcgacgtcagcgacggccgaccaccgagccaacggtttggaagggtctcccactccggac
ctcttgtcgccctccggctcccaggccaagagggtcaggcccctgtccaaggaagaccag
aagcaggcccggatcagaaagcagctgatgaccaagttcatcctgggctcttttgacgac
aactcttccgacgacgaggccgtggccggggcgttcaaggcctcttccaggaggagcagt
cgctcgagctttggctcctcatcttttgagacttcctctctactgggcctgacgaggtct
gaatccaccccgattatgaggcctagcatgtcaggactgcatttggtaaagaggggacga
gagcagaagaagctggaacagcaaagagacttcaccgtcgcctctccagctgagtttgtg
actcgttttggggggaatcgggtcattgagaaggtcctcatcgccaacaatggcatcgcc
gcagtcaagtgcatgcgctccatccgccgatgggcctatgagatgttccgcaacgagcgg
gccatccgcttcgtcgtcatggtaaccccagaggacctaaaagccaacgcagaatacatc
aaaatggccgatcattacgtgcccgtccctggcgggccaaacaacaacaattatgccaac
gtggagctgatcgtcgatatctctaagaggatcccagtacaggcggtgtgggccggctgg
ggacacgcctcggagaaccccaaacttcctgagctgctccacaaaaatggaattgccttt
ttaggtcctccgagtgaagccatgtgggccctgggggataaagtggcttccaccatagtg
gcccagacccttcagattccaaccttgccgtggagtggaagtggtttgtcggtggactgg
acggccagtgaccttcagcagatgaagaggatcagcgtaccccaagaggtgtatgtccgg
ggctgtgtgagagacgttgatgagggcttggaggcagcggaaaaaattgggttccccgtg
atgatcaaagcttccgaaggaggcgggggcaaaggcatcaggaaggccgagagtgctgag
gattttcccattctcttccgacaagtgcagagcgagatcccgggctcgcccgtgttcgtc
atgaagttggctcagcacgcccgccacttggaggttcagattctggcagaccagtatggc
agcgccgtgtccctcttcggccgagactgctccatccagcggcgacatcagaagatcatt
gaggaggccccggccaccgtcgccccaccggctgtattcgagtatatggagcagtgtgcc
gtgcgcctggccaaaaccgtgggctacgtgagcgcgggaacagtagagtacctatacagc
gacgacggcagcttccacttcctggagctcaacccccgcctgcaagtggaacacccctgc
actgaaatgatcgcggacgttaacttaccagccgcccaactccagattgcgatgggggtg
cctctcaacaggctgaaggacatccgcatattgtatggagagttaccctgggggatctta
cccatctcctttgaaaatcccacaaatcctccagtgcctcgaggccatgttatcgctgct
agaatcaccagtgaaaatcccgatgagggatttaagccgagctccgggaccgtccaggag
ttgaattttcgcagcagtaagaacgtgtggggttacttcagcgtggcagctgccggcggc
ttgcacgagtttgccgattcccagtttgggcactgcttctcctggggagagaaccgggaa
gaggccatttcgaacatggtggtggccctgaaagaactgtccatccgtggggatttccgc
accaccgtagaatatcttattaacctactagaaaccgaaagcttccaaggcaacgacatt
gacactggatggttggattaccttatcgcagagagggtccaggccgagaagcccgacatc
atgcttggggtcgtttgcggagccttgaatgtagccgacgccttgttcagaacctgtatg
accgacttcttgcactcccttgaaaggggccaggttctcccagccgcatctcttttaaac
attgtagatgtagagcttatttatgatggcgtcaaatatactctcaaggtggcccgtcag
tctctcactatgtttgtcctcataatgaacgacggtcacatcgagatagatgctcacagg
ctgaatgacgggggattgcttctgtcatatgatgggaacagttacaccacgtacatgaaa
gaagaaatcgatagttatcgaatcacgattggcaacaaaacgtgcgtgtttgagaaggag
aatgacccgacggtcctgaggtcgccttctgccgggaaactgctgcagtatacggtggag
gatggaggccatgtggtggctggaaacagctttgcggagatagaggtgatgaaaatgatc
atgaccttgaacgtccaagaaagcggccgggtctactacgtaaagcgccctggagcggtg
ctggaggcagggtgctcagtggccagactggaattggatgacccatccaaagtccacccg
gctgaaccattcacaggaaacctccctgcccagcaaaccttgcctattatgggggagaaa
ttgcaccaggttttccacaatgtgctagagaatctgaccaacgtcatgaatggctactgc
ttgccagaacctattttcagtgcaaagatcaaagaatgggtgtccaagctgctagtgact
ctgcgagacccttccttgcccctcctggagttgcaggagattatgaccagcgtgtccggc
cggatcccgccctccgtggagaagtcggtccgcaaagtgatggcccagtacgcgagtaac
atcacctctgtactctgccagttccccagccaacagatagcaaacgtgttggactgccat
gccgccaccttgcagcggaaggcggatagagaagttttcttcatgaacacgcaaagcatt
gtgcagctagtccagaggtaccgcagtggaacacgtggctatatgacagcagtggtgttg
gagttattaagaaaatacctacaagttgaacataattttcaacaagcacactatgacaaa
tgtgtcatcaacctcagggaacagttcaaaccggatatgtctcaagtgctggactgtatt
ttctcacatgcccaagtggccaagaagaacctgctggtgaccatgttaattgatgagctg
tgtggccctgatcccacactgaccgacgagctgctggccattctcaacgagctcacccaa
ctcagcaagaccgaacactccaaggtggccctcagagctaggcaggttttgatagcttct
caccttccttcctacgaattaaggcacaaccaagtagagtctatcttcctttccgccatc
gacttatacggacaccagttttgccccgacaacctgaagaaactgatcctgtctgaaacg
accatctttgatgttctgcccatgtttttctaccacgttaaccctgtggtctgcatggct
tccttggaggtgtatgtccggagaggatacatcgcctacgagttaaacagcctgcaacac
cggaaactcccggacggcacctgcgtagtagaattccagttcatgttgccttcgtctcat
ccaaaccggatgcacatccccatcagcgtgaccaaccccgacctggtccggcatagcacc
gagctcttcatggacagcggtttctccccgctgtgtcagaggatgggagccatggtcgcc
ttcacgaaattcgaggattttaccaggaattttgacgatgtcatttcctgcttcgccaac
ctgcccaaggactgtcccctgttccatgaggcccgatccaccctgtactgcgaggaggac
agcaaaaacgtgagggaagaacccatacatattttgaacgtggccatcaagtgcgcggat
cacctcgaggatgaagctcttgtgccagtcttccggacttttgtgcagtcgaagaaaaac
atcctggtggaatacggtctccggagaatcacatttttaatcgcccagcagagagaattt
cccaagttttttactttcagagcgagagatgagtttgccgaagacagaatctaccgccat
ctggagcccgctttggccttccagttggagctgaatcgaatgcggaactttgatctgacc
gccgtgccttgtgccaatcataagatgcatctttacctaggagccgccagggtggaagaa
ggtgctgaagtgaccgactataggttcttcatccgggccatcatcagacactctgacttg
attacgaaggaggcctccttcgagtatcttcagaatgaaggggaacggctgctcttggaa
gcgatggacgagctggaggtggccttcagtaataccaccgtccgcaccgactgcaaccac
atcttcctcaacttcgtccccacggtcatcatggacccttccaagatcgaagagtcggtt
cgctctatggtgatgcgctacgggagccgcctgtggaaacttcgtgtcctgcaagccgaa
gtcaagatcaatatccgcctgaccacgactggcaccgcaatccccattcgcctcttcctg
accaatgaatctggttactacctggacatcagcctctataaagaagtgacggatgccggg
actggaaacatcatgttcaactccttcggagataaagaaggtgctcagcatgggatgtta
atcaacactccgtacatgaccaaggacctgttacaagcgaagagattccaggcccaatcc
ctgggaactacttatgtttacgactttcccgaaatgttccggcaggctctgtttaaattg
tggggctcctcagacaagtaccccaaagatgtcctgacttgcacggagctggtgctggat
tctcagggccaactggtccagatgaacaggctacccggaggcaatgaggtgggcatggtg
gccttcaaaatgaagatgaagacccgagagtatcccgagggccgcgaagtgatcgtcatc
agcaatgacatcacgttcaagatcggctccttcggacagggggaagacctcctgttccta
cgggcttcggaactggcccgcgcccagggcatccccaggatctacctctcggccaacagc
ggggcccgtatcggcctggccgaggagatccgggacatgttccgggtggcctgggtggac
ccagaagacccttacaaagggttcaagtacctgtacctgactccccaagactacacccga
atcagctccttgaactctgtccactgtgagcatgtggaggaaggaggagaatccaggtac
gtgatcacggacatcatcgggaaggacgatgggctcggagtggagaacctgaggggctcg
ggcaccattgctggggagtcgtccctggcttatgaggaaatcgtcaccgtgagcatggtt
acttgccgggctctcggcattggggcctacctggtgcgactgggccagcgggtgatacag
gtggagaactcccatatcatcttgactggggccagtgctttgaacaaggtcctgggtcgt
gaagtctacacatccaataaccagttgggtggtgtacagataatgcatttcaatggcatt
tcccacatcacggttccagatgactttgagggagtctataccatcttggagtggctctct
tatatgcccaaggataatcggagcccggtgcctatcattacacccatggaccccattgac
cgagaaattgagtttgtcccttctaaagccccctatgatccccggtggatgttggctgga
agacctcatccaactgtgaaggggacgtggcagagtggcttctttgaccagagcagcttc
aaggagatcatggagccctgggcacagaccgtcgttactggcagggcaaggttgggtgga
atccccgttggggtaatcgcggtggagacgcggtccgttgagctggtcatcccagctgat
cccgctaatctggactctgaagcaaagatcatccagcaggccggccaggtttggttccca
gactcagcctttaaaactgcccaggccattaaagacttcgaccgggagaggctgcccctt
ctgatctttgccaactggagaggattctctggaggcatgaaagatatgtacgatcaggtg
atgaaatttggcgcctacatagtcgacggcctaaggcagtataaacagcccgtccttatt
tacattccaccgtacgctgagctcaggggaggatcgtgggtggtcattgatccgacaatc
aacccattctgcatggagctgtatgccgacaaagagagcagagggggcgtcttggagccc
gaaggaaccgtggagatcaagttccggaagaaagatttgataaaagccatgagaagaata
gatactgtgtatgggaagctcgtcgaacagctgggttcgccggaattgtcggagaaggat
cgcagagatctggagaggaaggtgaaagggcgggaggagctcctcttgcctatatatcac
caggtggcagtgcagtttgccgacctgcacgacaccccgggaagaatgcaagaaaaggga
gtcattacggatattttagagtggaaaaactcccgtacgttcttatactggcggctgcgt
cgactgctcctggagggtgtcgtgaaaaacgagatcctgctcgccaacagcgagctgagc
cacgtccacatccagtctatgctgcgtcgctggttcctggagacggagggcaccgtgaag
gggtacctctgggacaacaaccaagtggtggcagcgtggctggagaaacacctgcaggaa
gaggacggctcccgctccgccatccgggagaacatcaaatacctcaagcgggacttcgcc
ctcaagaacatccgaggcctggttcaggagcatcctgaggtggttatggactgcatcgtt
cacatgactcaacacatcagccccgcagaaagggcccaggtagcccacctgctcgccacc
ttggaaaacccctccacctga
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integrated database retrieval system
