Ornithorhynchus anatinus (platypus): 100077063
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Entry
100077063 CDS
T01045
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa04620
Toll-like receptor signaling pathway
oaa04621
NOD-like receptor signaling pathway
oaa04622
RIG-I-like receptor signaling pathway
oaa04623
Cytosolic DNA-sensing pathway
oaa04625
C-type lectin receptor signaling pathway
oaa04657
IL-17 signaling pathway
oaa04936
Alcoholic liver disease
oaa05160
Hepatitis C
oaa05161
Hepatitis B
oaa05162
Measles
oaa05164
Influenza A
oaa05165
Human papillomavirus infection
oaa05167
Kaposi sarcoma-associated herpesvirus infection
oaa05168
Herpes simplex virus 1 infection
oaa05169
Epstein-Barr virus infection
oaa05171
Coronavirus disease - COVID-19
oaa05207
Chemical carcinogenesis - receptor activation
oaa05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100077063 (IKBKE)
04621 NOD-like receptor signaling pathway
100077063 (IKBKE)
04622 RIG-I-like receptor signaling pathway
100077063 (IKBKE)
04623 Cytosolic DNA-sensing pathway
100077063 (IKBKE)
04625 C-type lectin receptor signaling pathway
100077063 (IKBKE)
04657 IL-17 signaling pathway
100077063 (IKBKE)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100077063 (IKBKE)
09172 Infectious disease: viral
05161 Hepatitis B
100077063 (IKBKE)
05160 Hepatitis C
100077063 (IKBKE)
05171 Coronavirus disease - COVID-19
100077063 (IKBKE)
05164 Influenza A
100077063 (IKBKE)
05162 Measles
100077063 (IKBKE)
05168 Herpes simplex virus 1 infection
100077063 (IKBKE)
05167 Kaposi sarcoma-associated herpesvirus infection
100077063 (IKBKE)
05169 Epstein-Barr virus infection
100077063 (IKBKE)
05165 Human papillomavirus infection
100077063 (IKBKE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100077063 (IKBKE)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100077063 (IKBKE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oaa01001
]
100077063 (IKBKE)
Enzymes [BR:
oaa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
100077063 (IKBKE)
Protein kinases [BR:
oaa01001
]
Serine/threonine kinases: Other
IKK family [OT]
100077063 (IKBKE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
RH_dom
Motif
Other DBs
NCBI-GeneID:
100077063
NCBI-ProteinID:
XP_028924172
Ensembl:
ENSOANG00000005385
UniProt:
F6VGZ1
LinkDB
All DBs
Position
7:62663645..62693488
Genome browser
AA seq
719 aa
AA seq
DB search
MQSTANYLWHTDDILGQGATASVYKARNKKSGELVAVKVFNNASYHRPPEVQVREFEVLR
KLKHQNIIKLFAVEETGNSKQKVLVMEYCARGSLLTVLEEPENAFGLPEEEFLVVLQCVV
AGINHLRENGIVHRDIKPGNIMRLVGEAGQSIYKLTDFGAARELADDEKFVSVYGTEEYL
HPDVYERAVLKKPQQKAFGVTVDLWSIGVTFYHAATGSLPFVPFGGPRRNKEIMFRMTSE
KPAGAIAGVQKRESGPLEWSYDLPTTCQLSGGLRAQLVPILANVLEVDQEKCWGFNQFFA
ETSDTLHRVVVHVFSLPQAVLHHVYVHAHNTTAVFLESVFKQTNIAPDHQEYLFEGHPCL
LEPSLPAQHLVKTSASSPLTLLSVEPKSPLGLTFRDPALDIPKFVPKVDLLADYNTAKGV
LGSGHRTLRLSQELHRGRELMLRGLTWLVEMLKSSCGHSLEKTRMALLFLNHSGQGQDRP
QLTSGSCEEPERRVVGELRARLQTISEILSGWPQSIQDTWSRLGSMAAELAKSREQVHED
RSIQQIECCLDKMQLIYKQFKKARMRPGLGYNEEQIHKLDKVNFVHLAKRLLRIFQDDCV
HKYQEALTMHGQRMREVHEIRKHLQLVNSTVAACSSEAQGTQECLREALDRLTQRLLQNR
LTAPPTSSPSLDVDLNSVPKELLLHMRELQEEMKSVTFDLQHNNSIIERLKEVTPAPVL
NT seq
2160 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacggccaactacctctggcatacagacgacatcctgggccagggggccacc
gccagtgtctacaaggctcgcaacaagaaatccggggagctggtggcagtgaaggtcttc
aacaatgccagctaccaccgtcccccggaggtgcaagtgcgggagtttgaggtcctgcgg
aaactgaagcatcagaacatcatcaaactgtttgccgtggaggaaactggcaacagcaag
cagaaggtgctggtgatggagtactgtgccagagggagcctgctgaccgtgctggaggag
cccgagaatgccttcggcctgcccgaggaagaattcctcgtggtgctgcaatgtgtggtt
gctggcatcaaccacctccgagagaatggcatcgtgcacagggacatcaagccaggaaac
atcatgcgtctggtgggcgaagccgggcagagcatatacaagctgacggacttcggcgcg
gcccgggaactggctgacgacgagaagttcgtgtcggtctacggcacggaagagtatctc
cacccagatgtatatgagagagccgtgctgaagaagccccagcaaaaggcttttggggtg
acggtggacctttggagcatcggagtcaccttctaccatgcggccacaggcagcctcccc
tttgtgcccttcggtgggccccggcggaacaaggagatcatgttccgcatgacctcggag
aagccggccggggccatcgcgggcgtccagaagcgggagagcggaccgctggagtggagc
tacgacctccccaccacctgccagctgtctggagggctgcgggcccagctggtgcctatc
ctggccaacgtcctggaggtggatcaggagaagtgctggggcttcaaccagttcttcgcc
gagaccagcgacacgctccacagggtcgtcgtccatgtcttctccctgccgcaggccgtc
ctgcaccacgtctacgtccacgcccacaacacgacggccgtattcctggaatcggtgttc
aaacaaaccaacattgcccccgaccaccaggagtatctatttgagggccacccctgcctc
ctggagcccagcctgcctgctcagcacctcgtgaaaacatcagcgagcagccccctaacc
ctgctcagcgtggagcccaagagtcccttgggcctgaccttccgggatccagccctcgac
atccccaagtttgtccctaaagtggacctgctggcggattacaacactgccaagggtgtg
ctgggctccgggcaccggacactgaggctttcccaggagctgcacaggggccgggagctg
atgctcaggggactcacctggctggtggaaatgctcaagtcctcctgtggacactccctg
gagaaaacacggatggcactactcttcctgaaccacagtggccagggtcaagacaggcct
cagctcacttctgggtcatgtgaggaaccagagcggcgagtcgtgggtgaactgagagcc
agacttcagactatcagtgagattctttccggatggccccagagtatccaggacacctgg
agccgcctgggcagcatggccgctgagctggcgaagagccgggaacaggtacatgaagac
agaagcatccagcagattgagtgctgcctggacaagatgcagcttatctacaagcagttc
aagaaagccaggatgcggccaggtttgggctacaatgaagagcagattcacaaacttgat
aaggtgaattttgtccatttagccaagagactgctacgtatcttccaagatgactgtgtt
cacaagtatcaggaggctctcaccatgcacggacagaggatgagagaggtgcacgagatc
cgcaagcatctgcagctggtgaacagcacggtggccgcctgcagctcggaagcccaggga
acccaggagtgcctcagggaggccctggacaggctcactcagcgcctccttcagaacaga
ctgactgcacctccaacctcttctccctccctggatgtggacttgaactctgttccgaag
gagctgcttctgcacatgcgggagctccaggaggagatgaagtcagtgacatttgatctc
cagcacaacaacagcatcattgagagattaaaggaggtcacacccgcccctgttctttga
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