Ornithorhynchus anatinus (platypus): 100077908 Help Entry 100077908         CDS       T01045                                  Symbol ADCY8 Name (RefSeq) adenylate cyclase type 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism oaa  Ornithorhynchus anatinus (platypus) Pathway oaa00230   Purine metabolism oaa01100   Metabolic pathways oaa01522   Endocrine resistance oaa04015   Rap1 signaling pathway oaa04020   Calcium signaling pathway oaa04022   cGMP-PKG signaling pathway oaa04024   cAMP signaling pathway oaa04062   Chemokine signaling pathway oaa04072   Phospholipase D signaling pathway oaa04081   Hormone signaling oaa04082   Neuroactive ligand signaling oaa04114   Oocyte meiosis oaa04211   Longevity regulating pathway oaa04213   Longevity regulating pathway - multiple species oaa04261   Adrenergic signaling in cardiomyocytes oaa04270   Vascular smooth muscle contraction oaa04371   Apelin signaling pathway oaa04540   Gap junction oaa04611   Platelet activation oaa04713   Circadian entrainment oaa04714   Thermogenesis oaa04720   Long-term potentiation oaa04723   Retrograde endocannabinoid signaling oaa04724   Glutamatergic synapse oaa04725   Cholinergic synapse oaa04727   GABAergic synapse oaa04742   Taste transduction oaa04750   Inflammatory mediator regulation of TRP channels oaa04911   Insulin secretion oaa04912   GnRH signaling pathway oaa04913   Ovarian steroidogenesis oaa04914   Progesterone-mediated oocyte maturation oaa04915   Estrogen signaling pathway oaa04916   Melanogenesis oaa04918   Thyroid hormone synthesis oaa04921   Oxytocin signaling pathway oaa04923   Regulation of lipolysis in adipocytes oaa04925   Aldosterone synthesis and secretion oaa04926   Relaxin signaling pathway oaa04927   Cortisol synthesis and secretion oaa04928   Parathyroid hormone synthesis, secretion and action oaa04934   Cushing syndrome oaa04935   Growth hormone synthesis, secretion and action oaa04970   Salivary secretion oaa04971   Gastric acid secretion oaa04972   Pancreatic secretion oaa04976   Bile secretion oaa05032   Morphine addiction oaa05163   Human cytomegalovirus infection oaa05166   Human T-cell leukemia virus 1 infection oaa05200   Pathways in cancer oaa05207   Chemical carcinogenesis - receptor activation oaa05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:oaa00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100077908 (ADCY8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100077908 (ADCY8)    04371 Apelin signaling pathway     100077908 (ADCY8)    04020 Calcium signaling pathway     100077908 (ADCY8)    04072 Phospholipase D signaling pathway     100077908 (ADCY8)    04024 cAMP signaling pathway     100077908 (ADCY8)    04022 cGMP-PKG signaling pathway     100077908 (ADCY8)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100077908 (ADCY8)    04081 Hormone signaling     100077908 (ADCY8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100077908 (ADCY8)   09144 Cellular community - eukaryotes    04540 Gap junction     100077908 (ADCY8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100077908 (ADCY8)    04062 Chemokine signaling pathway     100077908 (ADCY8)   09152 Endocrine system    04911 Insulin secretion     100077908 (ADCY8)    04923 Regulation of lipolysis in adipocytes     100077908 (ADCY8)    04912 GnRH signaling pathway     100077908 (ADCY8)    04913 Ovarian steroidogenesis     100077908 (ADCY8)    04915 Estrogen signaling pathway     100077908 (ADCY8)    04914 Progesterone-mediated oocyte maturation     100077908 (ADCY8)    04921 Oxytocin signaling pathway     100077908 (ADCY8)    04926 Relaxin signaling pathway     100077908 (ADCY8)    04935 Growth hormone synthesis, secretion and action     100077908 (ADCY8)    04918 Thyroid hormone synthesis     100077908 (ADCY8)    04928 Parathyroid hormone synthesis, secretion and action     100077908 (ADCY8)    04916 Melanogenesis     100077908 (ADCY8)    04925 Aldosterone synthesis and secretion     100077908 (ADCY8)    04927 Cortisol synthesis and secretion     100077908 (ADCY8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100077908 (ADCY8)    04270 Vascular smooth muscle contraction     100077908 (ADCY8)   09154 Digestive system    04970 Salivary secretion     100077908 (ADCY8)    04971 Gastric acid secretion     100077908 (ADCY8)    04972 Pancreatic secretion     100077908 (ADCY8)    04976 Bile secretion     100077908 (ADCY8)   09156 Nervous system    04724 Glutamatergic synapse     100077908 (ADCY8)    04727 GABAergic synapse     100077908 (ADCY8)    04725 Cholinergic synapse     100077908 (ADCY8)    04720 Long-term potentiation     100077908 (ADCY8)    04723 Retrograde endocannabinoid signaling     100077908 (ADCY8)   09157 Sensory system    04742 Taste transduction     100077908 (ADCY8)    04750 Inflammatory mediator regulation of TRP channels     100077908 (ADCY8)   09149 Aging    04211 Longevity regulating pathway     100077908 (ADCY8)    04213 Longevity regulating pathway - multiple species     100077908 (ADCY8)   09159 Environmental adaptation    04713 Circadian entrainment     100077908 (ADCY8)    04714 Thermogenesis     100077908 (ADCY8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100077908 (ADCY8)    05207 Chemical carcinogenesis - receptor activation     100077908 (ADCY8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100077908 (ADCY8)    05163 Human cytomegalovirus infection     100077908 (ADCY8)   09165 Substance dependence    05032 Morphine addiction     100077908 (ADCY8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100077908 (ADCY8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100077908 (ADCY8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100077908 (ADCY8) Enzymes [BR:oaa01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100077908 (ADCY8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD Motif Other DBs NCBI-GeneID:  100077908 NCBI-ProteinID:  XP_028918463 Ensembl:  ENSOANG00000008103 LinkDB All DBs Position 4:complement(5703182..5848513) Genome browser AA seq 1338 aa AA seqDB search MWTMCLDSYDSRRHLKRYIPEKYQLDVVDFPPALSHCTTLAYKNIAHQNIKSKTDDSQLY FEFYYRIGNIMVTFIKNPELLPLKERRKCHWFNFAQEIVCTCMLSKNNYSYVRTSNSKLN NLQLDELNSDQRHCKLENLAAYPFYVSLNDPFHMQQATAVRHITERRFVQGRGAAAGEAP RGAAPPGARAGRPAAAAAAPEAGPPGGLPEGEPAFPRLDRAPGNSDFFLHWGAAYRGVIF PTLRNAFKSRDLERLYQRYFLGQRRKSEVVVNVLDVLTKLTLLVLHLTLASAPMDPLKGI LLGFFTGIEVVICALAVARKDAASHAYLRYGGLVTWVAVTTQILAAGLGYGLLGDGVGYV LFTLFATYGMLPLPLAWAILAGLLTSALQIGLQMAVPRPVRVSVDQIVAQAVLFMCMNTA GIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVE DEHLQHQFHKIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHH CLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGS VLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERN EFLRKHNIETYLIKQPEESLLTLPEDIVKEAVSSVDKRNSGATFTEGSWSPELPFDNIVG KQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRRVHIKPFSLM FKDSSLEYKYSQMRDEVFKSNLVCAFIVLVFITAVQSLLPSSRMMPMVIQFSILIMLHSA LVLITTAEDYKCLPLVLRKSCCWINETYLARNVIIFASITINFLGAIINILWCDLDKTIL LKNQTFNSSVSFSDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYSLLTE TIYASLFLRYDNFNHNGEKDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQA KEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFAD FYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPDKQQC EDKWGHLCALADFSLALNESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGK TVNLASRMDSTGVSGRIQVPEETYLILNDRGFAFDYRGEIYVKGISEQEGKIKTYFLLGR VQPNPLILPPRKLPGQYSLAAVVLGLVQSLNRQRQKQILNENNNSGIIKGHYNRRTLLTS SGSEAVAQAESVDKPDLP NT seq 4017 nt NT seq  +upstreamnt  +downstreamnt atgtggaccatgtgtttagactcttatgactctagaagacatctcaaaaggtacattcca gaaaaataccagctggatgttgttgacttcccacctgccttatcccactgcacaacacta gcatataaaaacatagcacaccaaaatattaagagcaaaactgatgatagtcaactttat tttgaattttactacaggattgggaacataatggtgacatttataaagaatcctgagctc ttacctctgaaagagagaaggaaatgtcactggttcaattttgcacaggaaattgtctgt acatgtatgttgtcgaaaaacaattactcatacgtacgtacatccaactcaaagttgaat aaccttcagctggatgaactcaactcagatcaaaggcactgcaaactagagaacctggcc gcctatcccttctatgtcagcctaaatgatccatttcatatgcaacaggcgacggccgtg cgccacatcaccgagcgccgcttcgtccagggccggggggcggccgcgggcgaggccccc cgaggagcggcccctccgggcgcccgggccggccgccccgccgccgccgccgccgccccc gaggccggtccccccgggggcctccccgagggcgagccggccttcccgcgcctggaccgc gcgcccggcaactcggacttcttcctgcactggggggccgcttaccggggggtcatcttc cccaccctgcgcaacgccttcaagtcccgggacctggagcgcctctaccagcgctacttc ttgggccagcggcgcaagtcggaggtggtggtcaacgtcctggacgtgctcaccaagctg accctgctggtgctccacctgaccctggcctcggcccccatggacccgctcaagggcatc ctgctgggcttcttcacgggcatcgaggtggtcatctgcgccctggccgtggcccgcaag gacgccgcctcccacgcctacctgcgctacggcggcctggtgacctgggtggccgtcacc acccagatcctggccgccgggctgggctacggcctgctgggcgacggcgtcggctacgtg ctcttcaccctcttcgccacctacggcatgctgcccctgcccctggcctgggccatcctg gccgggctgctcacctcggccctccagatcggcctgcagatggccgtcccccggccggtc cgcgtctccgtcgaccagatagtggctcaggcggtgttatttatgtgtatgaacacagcg ggaattttcattagctacctgtcagacagagctcaacgccaagccttcctggagaccaga agatgtgtggaagcgaggctgaggctagaaacggagaaccagagacaggaacgactggtg ctgtcggtcttgcctcgcttcgtggtcctagaaatgatcaatgacatgaccaacgtggaa gacgaacacttgcaacaccagttccacaagatctatatccatcgctacgagaatgtcagc attctcttcgcagatgtgaaaggatttactaacctttctacgaccttgtcagcacaggag ctggtcaggatgttgaacgaactctttgccagatttgatcgactagcccatgagcatcac tgtcttcgaattaagatcctgggagactgctactactgtgtttctggactccctgaaccc cgtcaagaccatgcacactgctgtgtagaaatgggtctcagcatgatcaaaacaatcagg tatgtgagatcaagaacaaagcatgatgtcgacatgaggataggaattcactctggatca gtgttatgcggagtcctcggcctgcggaaatggcagttcgatgtgtggtcatgggatgtg gacattgcaaataaattagaatcaggtggaattcctgggcgaattcacatctcaaaagcc accctggactgcctcaacggtgattataatgttgaagaagggcacgggaaagagcgaaat gagttcttaaggaaacacaatatagagacctatttgataaagcagccagaggagagcctg ctgaccctgcctgaagacattgtgaaggaggcggtcagctccgtggataagcgaaacagt ggggccacatttaccgaaggatcgtggagccccgagcttccgttcgataacattgtgggg aaacagaatactttggctgccctaacaagaaattcaataaatctgcttccaaaccatctt gcacaagctttgcatgtccagtctgggcccgaggaaattaacaagcgaatagagcacacc atcgacttacggagtggcgataaattgagaagagtgcatatcaagcctttctcactgatg tttaaagactccagcctggagtataagtactcccagatgagagatgaagtcttcaagtca aacttggtctgtgcattcattgttcttgttttcatcacggcagtccaaagcttgcttcct tcttcaaggatgatgccaatggtcatccagttttccattctgattatgttgcactcggcc cttgtgctcatcaccactgccgaagactacaaatgtctgcctcttgtgctacgaaaaagt tgttgttggataaatgagacctatttggccaggaatgtgatcatctttgcctccatcacg attaattttctgggagcgatcataaatatcttgtggtgtgacttggacaagacgattcta ttgaagaaccagactttcaactcttcagtctccttctcggatatctgctcctaccctgag tattttgtctttaccggggtgctggccatggtgacttgtgccgtgttccttcggctcaac tctgtgctgaagctggcggtgttactgattatgatcgccatctactccctgctcacggag accatttatgcatcactctttcttcgctatgacaactttaatcacaatggagagaaagat ttcctggggaccaaagaagcatccctgctcctgatggcgatgtttctcctagctgtattt taccatgggcaacagctggaatacacagccagacttgacttcctgtggcgagtgcaggcc aaagaggagatcaatgaaatgaaggaactcagggagcacaatgagaatatgctccgtaac atcctacccagccacgtcgctcggcacttcctggagaaagaccgagacaacgaagaactg tactctcagtcctacgatgctgtcggagtgatgtttgcttctatcccgggatttgctgac ttttactctcagacggaaatgaataaccaaggagtggaatgtctgcgtctgctaaatgaa attatcgccgactttgatgagttactcggggaagaccgatttcaagacattgaaaagatt aaaaccattggcagcacctacatggctgtatcaggcttgtcacctgataaacagcaatgc gaagacaagtggggtcatttatgtgctctggctgacttctctcttgccctgaacgaaagc atccaggagatcaacaagcattcatttaacaattttgagctccgcattggtatcagccat ggatcggtggtggcgggggtgatcggcgcgaagaaaccacaatatgacatctggggcaaa acggtgaacctagccagtcgtatggacagcacaggggtgagcggcaggattcaagtcccc gaggagacgtacctcatcctaaacgaccgaggctttgcctttgactaccgaggagagatt tatgtcaagggcatcagcgagcaggaaggaaaaatcaaaacatattttcttctaggaaga gtacaaccaaatcctttaatcttaccaccaaggaaattgcctggacagtattccttagca gctgttgtcctcggacttgtacagtcacttaacaggcagaggcagaagcagatactgaat gagaacaacaactctggaataatcaagggacattacaaccgacggactttgttgacttcc agtggatctgaagccgtagctcaagcagaaagcgtggacaaacctgacttgccataa

DBGET integrated database retrieval system