Ornithorhynchus anatinus (platypus): 100080712 Help Entry 100080712         CDS       T01045                                  Symbol MDM2 Name (RefSeq) E3 ubiquitin-protein ligase Mdm2   KO K06643   E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] Organism oaa  Ornithorhynchus anatinus (platypus) Pathway oaa01522   Endocrine resistance oaa01524   Platinum drug resistance oaa04068   FoxO signaling pathway oaa04110   Cell cycle oaa04115   p53 signaling pathway oaa04120   Ubiquitin mediated proteolysis oaa04144   Endocytosis oaa04151   PI3K-Akt signaling pathway oaa04218   Cellular senescence oaa04625   C-type lectin receptor signaling pathway oaa04919   Thyroid hormone signaling pathway oaa05163   Human cytomegalovirus infection oaa05165   Human papillomavirus infection oaa05169   Epstein-Barr virus infection oaa05200   Pathways in cancer oaa05202   Transcriptional misregulation in cancer oaa05203   Viral carcinogenesis oaa05205   Proteoglycans in cancer oaa05206   MicroRNAs in cancer oaa05214   Glioma oaa05215   Prostate cancer oaa05218   Melanoma oaa05219   Bladder cancer oaa05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:oaa00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     100080712 (MDM2)  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     100080712 (MDM2)    04151 PI3K-Akt signaling pathway     100080712 (MDM2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     100080712 (MDM2)   09143 Cell growth and death    04110 Cell cycle     100080712 (MDM2)    04115 p53 signaling pathway     100080712 (MDM2)    04218 Cellular senescence     100080712 (MDM2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100080712 (MDM2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     100080712 (MDM2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100080712 (MDM2)    05202 Transcriptional misregulation in cancer     100080712 (MDM2)    05206 MicroRNAs in cancer     100080712 (MDM2)    05205 Proteoglycans in cancer     100080712 (MDM2)    05203 Viral carcinogenesis     100080712 (MDM2)   09162 Cancer: specific types    05214 Glioma     100080712 (MDM2)    05220 Chronic myeloid leukemia     100080712 (MDM2)    05218 Melanoma     100080712 (MDM2)    05219 Bladder cancer     100080712 (MDM2)    05215 Prostate cancer     100080712 (MDM2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     100080712 (MDM2)    05169 Epstein-Barr virus infection     100080712 (MDM2)    05165 Human papillomavirus infection     100080712 (MDM2)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100080712 (MDM2)    01522 Endocrine resistance     100080712 (MDM2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oaa04131]     100080712 (MDM2)    04121 Ubiquitin system [BR:oaa04121]     100080712 (MDM2) Enzymes [BR:oaa01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      100080712 (MDM2) Membrane trafficking [BR:oaa04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     100080712 (MDM2) Ubiquitin system [BR:oaa04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    MDM2/MDM4 proteins     100080712 (MDM2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-C3HC4_3 SWIB Zn_ribbon_RanBP zf-RING_2 FTA4 zf-FPG_IleRS Motif Other DBs NCBI-GeneID:  100080712 NCBI-ProteinID:  XP_028934347 LinkDB All DBs Position 14:17113161..17140107 Genome browser AA seq 487 aa AA seqDB search MCRTEMSSATDPALGPSAAAPSEPEALVRPKPLLSKLLKLAGAQKDTFTMKEVIFYLGQY IMAKQLYDEKQQHIVHCSNDLLGDLFGVPSFSVKEHRRLYAMVSRNLIAVSRQEPIGAET SNSETRCQLETGNPPKETVQELPEEKPASPNLTSRPTTSSRRRTHSETDENLDELPSERQ RKRHKSDSISLTFDESLALCVISELCCDRSNSSDSNDIPSNPDLDAPSSSENSDDWCDRE SISDQFSVEFEVESIDSEDYSHNEEGQELTDEDDEVYQVTLYQTEESDADSFDEDPEISL ADYWKCSSCDEMNPPLPSHCHRCWSLRENWLPDEKAESLEKGDLESSPQEEAGFDVPDCK KIKATEGKESPVEGSDDPGKTLDSQESEEYSQPSTSNSIIYSSQEDAKESGREESRDREE NEDSKLPLSTIEPCVICQSRPKNGCILHGRTGHLMACFTCAKKLKKRNKPCPVCRQPIQM IVLTYFS NT seq 1464 nt NT seq  +upstreamnt  +downstreamnt atgtgtcgcaccgagatgtcttccgccacagaccccgccctcggcccctcggccgccgca ccttccgagccggaggccctggttagaccaaagccactcctttcgaagttattaaaactt gctggtgcacagaaagacacttttacaatgaaggaggttatattttatcttgggcaatat ataatggcaaaacaattatatgatgaaaagcagcaacacattgtccattgctcaaatgat cttcttggagatctgtttggagtaccaagcttctctgtgaaggaacacaggagattatat gcaatggtttccagaaacttgatagctgtcagccgtcaagaacctataggggcagagaca agtaacagcgagaccaggtgtcaactggaaactgggaatcctccaaaggagacagtgcaa gagttgccagaagagaaacctgcatcaccaaatttaacttctagaccaactacctcatct aggaggaggactcatagtgaaacagacgagaacctagatgaattacccagcgaaagacaa agaaaacgacacaaatcggatagcatttcgctcaccttcgatgaaagccttgcgctttgt gtgataagtgagctgtgctgtgaccggagcaacagtagtgactcaaatgacattccctcc aatccagatctcgatgctccgtcttcgagtgaaaattctgatgattggtgtgatcgagag tccatttcagaccaatttagtgttgagtttgaagttgaatctattgactctgaagattat agccacaatgaagaagggcaggaactcacagatgaagatgatgaggtataccaggtaact ttgtatcaaacagaagaaagtgatgcagactcatttgatgaagatcctgaaatatccttg gcagattattggaagtgctcttcttgtgatgaaatgaatcccccgctcccatcccactgc cacagatgttggtctctccgggagaactggcttcccgacgagaaggccgagtcgcttgag aaaggcgacttagaaagctcgccccaagaagaagcgggcttcgatgttcctgactgtaaa aagattaaagcgacggaaggtaaagaatcgcccgttgaaggaagcgatgacccaggcaaa accctggattcccaggagagcgaggaatactctcaaccgtccacttctaacagcatcatc tatagcagccaagaggatgccaaggagtcggggcgagaagaatcccgagacagagaggaa aacgaggactccaagcttccccttagcaccatagaaccctgcgtcatttgtcagagcaga ccgaaaaatggctgcatcctccatggcaggacaggacacctcatggcttgtttcacatgc gccaagaagctgaaaaaacgaaacaagccctgtccggtgtgtaggcagccgattcagatg atcgtgctgacttatttcagctag

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