Ornithorhynchus anatinus (platypus): 100081193
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Entry
100081193 CDS
T01045
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa04137
Mitophagy - animal
oaa04140
Autophagy - animal
oaa04141
Protein processing in endoplasmic reticulum
oaa04210
Apoptosis
oaa04932
Non-alcoholic fatty liver disease
oaa05010
Alzheimer disease
oaa05012
Parkinson disease
oaa05014
Amyotrophic lateral sclerosis
oaa05020
Prion disease
oaa05022
Pathways of neurodegeneration - multiple diseases
oaa05160
Hepatitis C
oaa05162
Measles
oaa05168
Herpes simplex virus 1 infection
oaa05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100081193 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100081193 (EIF2AK3)
04137 Mitophagy - animal
100081193 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
100081193 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
100081193 (EIF2AK3)
05162 Measles
100081193 (EIF2AK3)
05168 Herpes simplex virus 1 infection
100081193 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
100081193 (EIF2AK3)
05012 Parkinson disease
100081193 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
100081193 (EIF2AK3)
05020 Prion disease
100081193 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
100081193 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100081193 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100081193 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oaa01001
]
100081193 (EIF2AK3)
Enzymes [BR:
oaa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100081193 (EIF2AK3)
Protein kinases [BR:
oaa01001
]
Serine/threonine kinases: Other
PEK family [OT]
100081193 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Kdo
PQQ_2
ABC1
APH
Motif
Other DBs
NCBI-GeneID:
100081193
NCBI-ProteinID:
XP_028902324
Ensembl:
ENSOANG00000010350
LinkDB
All DBs
Position
18:complement(28002110..28055796)
Genome browser
AA seq
954 aa
AA seq
DB search
MIIPSLDGDLFQWDRDRESMEAVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGK
VRYICSAMGCRRWDDDEIEQEDILLLHRTQKTVRAVGPRSGNEKWNFSVGHFELRYVPDV
ETRVGFLESNFKSGVNREESTIISDVEEQEAVMKDTVIKVSVADWKIMAFNKKGGHLEWE
YQFCTPIASAWLVKDGKVIPISLFDDTSYTSDSGILEDEEDIVEAARGATESSVYLGMYR
GQLYLQSSVRISEKFPTNPKALESINNENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDK
CLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERSKRSTQITVRFFDNMNYNKNVRK
KDPVLLLHWWKEIAGTILFCIIATTLIVRRLFHPNPHRQQRKESETQCQTDNKYDSISGE
ISDSSWSDIKTSGYVSRYLTDFEPIQCMGRGGFGVVFEARNKVDDCNYAIKRIRLPNRDL
AREKVMREVKALAKLEHPGIVRYFNAWLEAPPEKWQEKMDELWLKDESTDWPLSSPSPMD
APSVKIRRVDPFSTRERVEIIAPSPQRNKSFSVGISCSQSSSSESQFSPLEFSEVENGNN
SESEDPGFNLRDSCLTDCDVEDGTVDGNDEGHSFELCPSAASPYVRSGERTSSSIVFEDS
GCDNTSSKEDHKTLALHNGNRSPDRLISTKDSPSESLLSISPPRPTTLSLDLTRNVTEKL
QPTSPKVYLYIQMQLCRKENLKDWMNRRCNIEDRERTVCLQIFLQIAEAVEFLHSKGLMH
RDLKPSNIFFTMDDVVKVGDFGLVTAMDQDEEEQSVLTPMPAYARHTGQVGTKLYMSPEQ
ICGNSYSHKVDIFSLGLILFELLYPFSTQMERVRILSEVRNLKFPPLFATKYPQEYTMVQ
HMLSPSPTERPEATAIIENALFEDLEIPVKTVLRQRSRSLSSSGMKHSRQPSSS
NT seq
2865 nt
NT seq
+upstream
nt +downstream
nt
atgatcattccttccttggatggagacctcttccagtgggatcgagatcgggagagcatg
gaagcggttccttttacggttgaatctctgcttgagtcatcttacaaatttggagatgat
gttgttttggttggaggaaagtctcttactacctatggcttaagtgcatatagtggcaag
gtgcgttatatttgttcagcgatgggttgtcgccgttgggatgatgatgaaatagaacag
gaagatattctcctccttcatcgaacacaaaagactgtcagagctgttggaccccgcagc
ggcaatgagaagtggaatttcagcgtcggccactttgagctgcgatacgtaccagatgtg
gaaacccgagttggatttcttgaaagtaattttaaatccggtgtaaacagagaagagtcc
accataatttccgacgtggaagaacaagaagccgtcatgaaggacacagtgataaaggtc
tcagttgccgactggaagattatggcttttaataagaagggaggtcatctggagtgggaa
taccagttttgcacgccgattgcttctgcctggctggttaaagatgggaaggtcattccg
atcagtcttttcgatgacaccagttacacgtcggacagcggaatcctagaggatgaagag
gacatcgtggaagccgccagaggagccacggagtctagtgtctatttaggaatgtacaga
ggccagctgtacctgcagtcatcagtcaggatttctgaaaaatttcccaccaacccgaag
gctttggaatctatcaataatgaaaatgccatcattcctttgcccaccatcaagtggaaa
cctttaattcattctccttctaggactcctgttttggtgggctctgacgaatttgacaaa
tgtcttagcaatgacaagttttctcatgaagagtacagcaatggtgccctctcaattttg
cagtatccatatgacaacggttattatttaccatactacaagagggagaggagcaagcgg
agcacacagatcacagttaggttttttgacaacatgaactacaacaagaatgtgcgtaaa
aaagatcctgtcctcctgctacactggtggaaggaaatagcgggcaccattctgttttgc
atcatagcaacgactttgatcgtgcgccgactcttccatcctaatcctcacaggcagcag
cggaaagaatctgaaacccagtgtcagactgataataaatatgattccataagtggtgaa
ataagcgacagtagctggagtgacattaagacctctggatatgtatcaagatacctaaca
gattttgaaccaatacagtgtatgggccgtggaggattcggagtggtcttcgaagccaga
aacaaagtagatgactgcaattatgccatcaagaggatccgtctccccaatagggatttg
gcccgtgagaaggtgatgcgagaagttaaagctttagctaagcttgagcatccaggaatt
gtgagatatttcaatgcctggctggaagcaccacctgaaaaatggcaggaaaagatggat
gaactgtggctgaaagatgaaagcacggactggcctctcagctcacccagcccaatggat
gcaccgtccgttaaaatccggagagtggatcccttctccacgagagaacgtgttgaaatc
atagccccttcacctcagagaaacaaatccttttccgtagggatttcctgtagtcaatca
agttcctcagagagccagttctcacccctggaattctcagaagtggaaaatggcaacaac
agcgaatcagaagatccagggttcaacctccgggacagctgcctcaccgactgcgatgtt
gaagatggcactgtcgatgggaacgatgaagggcactcttttgaactgtgtccttcagca
gctagcccctacgtgaggtcaggcgagagaacctcctcttccattgtatttgaagattct
ggttgtgacaacacatccagtaaggaagaccacaaaaccctggcattgcataatggcaac
cgctctcctgatagactcatcagtacaaaagactctccttctgaaagcctcctgtccatt
tctcctccaagaccgacgaccttaagtttggacctcaccagaaacgtcacggaaaaactt
cagcccacttcaccaaaggtgtacctctacattcagatgcaactgtgtaggaaggaaaac
ctcaaagactggatgaacagacggtgcaacatcgaggaccgagaacggacggtgtgcctg
cagatcttcctgcagatagcggaggctgttgagtttttgcacagtaaaggcctaatgcac
agggacctcaagccttccaacatattctttacaatggatgatgtggtaaaagttggggat
tttggactggtgactgctatggaccaggatgaggaagagcaatcggttcttaccccgatg
ccagcttatgcccgacacactggtcaagtgggaaccaaactgtacatgagcccagagcag
atttgtgggaacagttattctcataaagtggacatcttctctttgggtctgattctgttt
gaattgctctacccattcagcactcagatggagagagtcagaattttaagtgaagtaagg
aatctcaaatttccaccactctttgcaacaaaataccctcaagagtacaccatggtccag
cacatgctctctccatctccgacggagaggccggaggctacagctatcattgaaaatgcc
ttatttgaggacctggaaatcccagtaaagacagtgctcaggcagaggtcccgctccctg
agttcgtcaggaatgaagcactcgagacagccgagcagcagctga
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