KEGG   Ornithorhynchus anatinus (platypus): 100081438
Entry
100081438         CDS       T01045                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa00670  One carbon pool by folate
oaa00790  Folate biosynthesis
oaa01100  Metabolic pathways
oaa01240  Biosynthesis of cofactors
oaa01523  Antifolate resistance
oaa04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100081438 (DHFR)
   00670 One carbon pool by folate
    100081438 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100081438 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100081438 (DHFR)
Enzymes [BR:oaa01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100081438 (DHFR)
SSDB
Motif
Pfam: DHFR_1 YidX_N Beta-prop_RSE1_2nd
Other DBs
NCBI-GeneID: 100081438
NCBI-ProteinID: XP_028915410
Ensembl: ENSOANG00000001607
UniProt: A0A6I8NIG7
LinkDB
Position
1:21270501..21285821
AA seq 187 aa
MGPLLNCIVAVAKNGGIGNKGDLPWPALRNEFRYFQKMTTTPTVKGKQNLVIMGKKTWFS
IPEKSRPLKDRINIVLSRELKEPPQGAHYVAKSLDDALNLLHLPELASKVDMVWIIGGSS
VYKEAMEKGGHQRLFVTRILQDFESDTFFPEIDLEKYKLIPEYPGVPADTQEEKGIQYRF
EVYEKHI
NT seq 564 nt   +upstreamnt  +downstreamnt
atgggcccgctgctcaactgcatcgtggccgtggccaagaacgggggcatcggaaataaa
ggggacctgccctggcccgcgctcaggaacgaattcagatattttcagaaaatgaccaca
actccaacagtaaaaggtaaacaaaatctggtgataatgggtaagaagacctggttctcc
attcctgagaaaagtcgacctttgaaagacagaattaatatagtgctcagcagagaacta
aaagaacccccacaaggagctcattatgttgccaaaagtctggatgatgctctaaatctt
ctccacctcccagaactagcaagtaaagtggatatggtatggatcattggaggcagctca
gtttataaggaagcaatggagaaaggaggtcatcagcgactatttgtgactagaattttg
caagactttgaaagtgacacattttttccagaaattgatttagagaaatataaacttatt
ccggagtatcctggtgttccagctgacacccaggaagaaaagggcattcagtacagattt
gaagtatacgaaaagcatatttag

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