Ornithorhynchus anatinus (platypus): 100085643 Help Entry 100085643         CDS       T01045                                  Symbol TNF Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism oaa  Ornithorhynchus anatinus (platypus) Pathway oaa01523   Antifolate resistance oaa04010   MAPK signaling pathway oaa04060   Cytokine-cytokine receptor interaction oaa04061   Viral protein interaction with cytokine and cytokine receptor oaa04064   NF-kappa B signaling pathway oaa04071   Sphingolipid signaling pathway oaa04150   mTOR signaling pathway oaa04210   Apoptosis oaa04217   Necroptosis oaa04350   TGF-beta signaling pathway oaa04380   Osteoclast differentiation oaa04612   Antigen processing and presentation oaa04620   Toll-like receptor signaling pathway oaa04621   NOD-like receptor signaling pathway oaa04622   RIG-I-like receptor signaling pathway oaa04625   C-type lectin receptor signaling pathway oaa04640   Hematopoietic cell lineage oaa04650   Natural killer cell mediated cytotoxicity oaa04657   IL-17 signaling pathway oaa04660   T cell receptor signaling pathway oaa04664   Fc epsilon RI signaling pathway oaa04668   TNF signaling pathway oaa04920   Adipocytokine signaling pathway oaa04930   Type II diabetes mellitus oaa04931   Insulin resistance oaa04932   Non-alcoholic fatty liver disease oaa04933   AGE-RAGE signaling pathway in diabetic complications oaa04936   Alcoholic liver disease oaa04940   Type I diabetes mellitus oaa05010   Alzheimer disease oaa05014   Amyotrophic lateral sclerosis oaa05020   Prion disease oaa05022   Pathways of neurodegeneration - multiple diseases oaa05132   Salmonella infection oaa05133   Pertussis oaa05134   Legionellosis oaa05135   Yersinia infection oaa05140   Leishmaniasis oaa05142   Chagas disease oaa05143   African trypanosomiasis oaa05144   Malaria oaa05145   Toxoplasmosis oaa05146   Amoebiasis oaa05152   Tuberculosis oaa05160   Hepatitis C oaa05161   Hepatitis B oaa05163   Human cytomegalovirus infection oaa05164   Influenza A oaa05165   Human papillomavirus infection oaa05166   Human T-cell leukemia virus 1 infection oaa05168   Herpes simplex virus 1 infection oaa05169   Epstein-Barr virus infection oaa05170   Human immunodeficiency virus 1 infection oaa05171   Coronavirus disease - COVID-19 oaa05205   Proteoglycans in cancer oaa05310   Asthma oaa05321   Inflammatory bowel disease oaa05322   Systemic lupus erythematosus oaa05323   Rheumatoid arthritis oaa05330   Allograft rejection oaa05332   Graft-versus-host disease oaa05410   Hypertrophic cardiomyopathy oaa05414   Dilated cardiomyopathy oaa05417   Lipid and atherosclerosis oaa05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:oaa00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100085643 (TNF)    04350 TGF-beta signaling pathway     100085643 (TNF)    04064 NF-kappa B signaling pathway     100085643 (TNF)    04668 TNF signaling pathway     100085643 (TNF)    04071 Sphingolipid signaling pathway     100085643 (TNF)    04150 mTOR signaling pathway     100085643 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     100085643 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     100085643 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100085643 (TNF)    04217 Necroptosis     100085643 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     100085643 (TNF)    04620 Toll-like receptor signaling pathway     100085643 (TNF)    04621 NOD-like receptor signaling pathway     100085643 (TNF)    04622 RIG-I-like receptor signaling pathway     100085643 (TNF)    04625 C-type lectin receptor signaling pathway     100085643 (TNF)    04650 Natural killer cell mediated cytotoxicity     100085643 (TNF)    04612 Antigen processing and presentation     100085643 (TNF)    04660 T cell receptor signaling pathway     100085643 (TNF)    04657 IL-17 signaling pathway     100085643 (TNF)    04664 Fc epsilon RI signaling pathway     100085643 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     100085643 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     100085643 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100085643 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100085643 (TNF)    05170 Human immunodeficiency virus 1 infection     100085643 (TNF)    05161 Hepatitis B     100085643 (TNF)    05160 Hepatitis C     100085643 (TNF)    05171 Coronavirus disease - COVID-19     100085643 (TNF)    05164 Influenza A     100085643 (TNF)    05168 Herpes simplex virus 1 infection     100085643 (TNF)    05163 Human cytomegalovirus infection     100085643 (TNF)    05169 Epstein-Barr virus infection     100085643 (TNF)    05165 Human papillomavirus infection     100085643 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     100085643 (TNF)    05135 Yersinia infection     100085643 (TNF)    05133 Pertussis     100085643 (TNF)    05134 Legionellosis     100085643 (TNF)    05152 Tuberculosis     100085643 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     100085643 (TNF)    05144 Malaria     100085643 (TNF)    05145 Toxoplasmosis     100085643 (TNF)    05140 Leishmaniasis     100085643 (TNF)    05142 Chagas disease     100085643 (TNF)    05143 African trypanosomiasis     100085643 (TNF)   09163 Immune disease    05310 Asthma     100085643 (TNF)    05322 Systemic lupus erythematosus     100085643 (TNF)    05323 Rheumatoid arthritis     100085643 (TNF)    05321 Inflammatory bowel disease     100085643 (TNF)    05330 Allograft rejection     100085643 (TNF)    05332 Graft-versus-host disease     100085643 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     100085643 (TNF)    05014 Amyotrophic lateral sclerosis     100085643 (TNF)    05020 Prion disease     100085643 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     100085643 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100085643 (TNF)    05418 Fluid shear stress and atherosclerosis     100085643 (TNF)    05410 Hypertrophic cardiomyopathy     100085643 (TNF)    05414 Dilated cardiomyopathy     100085643 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100085643 (TNF)    04940 Type I diabetes mellitus     100085643 (TNF)    04936 Alcoholic liver disease     100085643 (TNF)    04932 Non-alcoholic fatty liver disease     100085643 (TNF)    04931 Insulin resistance     100085643 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     100085643 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     100085643 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:oaa04052]     100085643 (TNF)    00536 Glycosaminoglycan binding proteins [BR:oaa00536]     100085643 (TNF) Cytokines and neuropeptides [BR:oaa04052]  Cytokines   Tumor necrosis fators    100085643 (TNF) Glycosaminoglycan binding proteins [BR:oaa00536]  Heparan sulfate / Heparin   Cytokines    100085643 (TNF) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  100085643 NCBI-ProteinID:  XP_028911828 LinkDB All DBs Position X5:complement(8125205..8128181) Genome browser AA seq 225 aa AA seqDB search MSTESMLRDIELAGEPAGKTAGAQRPGHCLCLSLVSFLLVAGATTLFCLLHFGVIGPQDR EDGPLLPLTQMLKSYQPSAEKPAAHVVANSQEDKKLVWVGGRANALLEGNVILDKNQLVV PASGLYLVYSQILFKDSSCPANPDDSPILTHNVSRFSDSYEYEVSILSAIKTPCQGGAKG TWYEPIYQGGIFRLNQGDRLSSQTNSPEYLDFSMEGQVYFGIIAL NT seq 678 nt NT seq  +upstreamnt  +downstreamnt atgagcacggagagcatgctgagggacatcgaactggccggggagccggcggggaagacc gcgggggcccagaggcccggccactgcctctgcctcagcctcgtttccttcctcctcgtg gccggtgccaccacgctcttctgcctgcttcattttggggtcattggccctcaggaccga gaggatggccctctcctcccgctcacgcagatgctaaaatcttatcagccttcagcggag aagcctgctgcccacgttgtagccaattcccaggaggacaagaagctggtctgggtgggc ggccgtgccaacgccctgctggaaggcaacgtgatcctggacaaaaaccagctggtggtc cctgcctccggcctctacctcgtctactcccagatcctgttcaaggacagcagctgcccc gccaatcccgacgactcccccatcctgacccacaacgtctcccgcttctccgactcctac gagtacgaagtctccatcctctcggccatcaagacgccctgccagggcggggccaagggc acctggtacgagcccatctaccaggggggcatcttcaggctgaatcagggggacaggctc agctcccagaccaacagccccgaatatctggacttttccatggaagggcaagtgtatttc ggcatcattgccctgtga

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