Ornithorhynchus anatinus (platypus): 100089978
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Entry
100089978 CDS
T01045
Symbol
PTPN11
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 11
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
oaa
Ornithorhynchus anatinus (platypus)
Pathway
oaa04014
Ras signaling pathway
oaa04072
Phospholipase D signaling pathway
oaa04148
Efferocytosis
oaa04360
Axon guidance
oaa04625
C-type lectin receptor signaling pathway
oaa04630
JAK-STAT signaling pathway
oaa04650
Natural killer cell mediated cytotoxicity
oaa04660
T cell receptor signaling pathway
oaa04670
Leukocyte transendothelial migration
oaa04722
Neurotrophin signaling pathway
oaa04920
Adipocytokine signaling pathway
oaa04931
Insulin resistance
oaa05168
Herpes simplex virus 1 infection
oaa05205
Proteoglycans in cancer
oaa05208
Chemical carcinogenesis - reactive oxygen species
oaa05211
Renal cell carcinoma
oaa05220
Chronic myeloid leukemia
oaa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
oaa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100089978 (PTPN11)
04630 JAK-STAT signaling pathway
100089978 (PTPN11)
04072 Phospholipase D signaling pathway
100089978 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100089978 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
100089978 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
100089978 (PTPN11)
04660 T cell receptor signaling pathway
100089978 (PTPN11)
04670 Leukocyte transendothelial migration
100089978 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
100089978 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
100089978 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
100089978 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100089978 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
100089978 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100089978 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100089978 (PTPN11)
05211 Renal cell carcinoma
100089978 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
100089978 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100089978 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
oaa01009
]
100089978 (PTPN11)
Enzymes [BR:
oaa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
100089978 (PTPN11)
Protein phosphatases and associated proteins [BR:
oaa01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
100089978 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
100089978
NCBI-ProteinID:
XP_028907739
LinkDB
All DBs
Position
2:20632859..20691355
Genome browser
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQDLKYD
VGGGEKFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNTKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPGGVLDFLEEVHHKQENITDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLADQTSGDQXPLPPCTPTPTCPEMRDDSARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatccaggagatggtttcacccaaatatcaccggagtggaggcagagaatttactg
ctgacgagaggagttgatggcagtttcttggctaggcccagtaagagtaatccaggagac
ttcacactttccgttaggcgaaatggagccgtcacccacatcaaaattcaaaatactggg
gattactacgatctctatggaggagagaagtttgccacgctggctgaattagtgcagtac
tatatggaacatcatgggcagttgaaagagaagaatggagatgtgatcgagctcaagtat
ccactgaactgtgcagatcctacctcggaaaggtggttccatgggcacctctctgggaag
gaagcagagaaactattaactgagaaaggaaagcatggaagcttccttgttcgagaaagc
cagagccatccgggagactttgttctctccgtccgcacgggggatgataaaggagagagt
aatgatggcaaatctaaagtgactcatgtcatgattcgctgtcaggatctgaagtatgat
gttggaggaggagagaagtttgactctttgacagatctcgtggaacattataagaagaat
ccgatggttgagactttgggcacggtacttcagctgaagcagcctctgaatacaacccgt
ataaatgccgcggagatcgaaagccgtgtgagagaactgagcaagttggccgagaccaca
gataaagtcaagcaaggtttttgggaagaatttgagactttacagcaacaggaatgcaag
cttctctacagccgaaaagagggccaacggcaagaaaacaaaaacaaaaacagatacaaa
aacattttaccctttgatcataccagagtcgtcctacatgacggtgatcccaatgagcca
gtgtcagattacattaatgccaatattataatgcctgaatttgaaaccaagtgcaacaac
acaaaacccaaaaagagttatatcgcgacccaaggttgtcttcagaacacagtgaatgat
ttttggagaatggtgttccaggagaattctcgagttattgtcatgacaacgaaagaagtt
gaaagagggaagagtaaatgtgtcaaatactggccggatgaatacgcgttaaaggaatac
ggagtcatgcgagtcaggaacgtcaaagagagcgcagctcatgattataccttacgagag
cttaaactctcaaaggttggacaagggaacacagaaaggacagtttggcaatatcatttt
agaacctggcccgatcacggagtccctagcgatcctggtggtgttctggactttttagag
gaggtccaccacaagcaggagaacatcaccgacgccgggcctgtggtggtacattgcagt
gctggaatcggccggacgggaacgttcatcgtgattgatatccttattgacatcatcaga
gagaaaggggtggactgtgacatcgacgttcccaagaccatccagatggtgagatctcag
aggtcagggatggtccagacggaagcacagtaccgattcatatacatggccgtgcagcac
tacattgaaacactacagcgcagaattgaagaggaacagaaaagcaagagaaaaggacac
gagtacacaaatattaagtattccctagcggaccagacgagtggagatcagnagcccctt
ccaccctgcacaccaactccaacctgcccagaaatgagagacgatagcgccagagtatat
gaaaatgtgggcttgatgcagcagcagaaaagctttagatga
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