Ornithorhynchus anatinus (platypus): 114805830 Help Entry 114805830         CDS       T01045                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism oaa  Ornithorhynchus anatinus (platypus) Pathway oaa04022   cGMP-PKG signaling pathway oaa04068   FoxO signaling pathway oaa04081   Hormone signaling oaa04140   Autophagy - animal oaa04152   AMPK signaling pathway oaa04211   Longevity regulating pathway oaa04213   Longevity regulating pathway - multiple species oaa04910   Insulin signaling pathway oaa04920   Adipocytokine signaling pathway oaa04923   Regulation of lipolysis in adipocytes oaa04930   Type II diabetes mellitus oaa04931   Insulin resistance oaa04932   Non-alcoholic fatty liver disease oaa04935   Growth hormone synthesis, secretion and action oaa05010   Alzheimer disease oaa05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:oaa00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     114805830 (IRS2)    04022 cGMP-PKG signaling pathway     114805830 (IRS2)    04152 AMPK signaling pathway     114805830 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     114805830 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     114805830 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     114805830 (IRS2)    04923 Regulation of lipolysis in adipocytes     114805830 (IRS2)    04920 Adipocytokine signaling pathway     114805830 (IRS2)    04935 Growth hormone synthesis, secretion and action     114805830 (IRS2)   09149 Aging    04211 Longevity regulating pathway     114805830 (IRS2)    04213 Longevity regulating pathway - multiple species     114805830 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     114805830 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     114805830 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     114805830 (IRS2)    04932 Non-alcoholic fatty liver disease     114805830 (IRS2)    04931 Insulin resistance     114805830 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  114805830 NCBI-ProteinID:  XP_028903726 LinkDB All DBs Position 20:complement(10876260..10932191) Genome browser AA seq 959 aa AA seqDB search MASPAAAAAAAAAAAGCNLNNNNNHPSGVRKCGYLRKQKHGHKRFFVLRGPGPPAQPARL EYYDSEKKWRSKAAAPKRVISLDSCLNVNKRADAKHKYLIALYTRDEYFAVAADDEREQD GWYRALTDLLSEGKAGPEASSGCSSCSSSSLPSPASPAPAVEEPPAGAAYREVWQVNLKP KGLGHTKNLTGVYRLCLAARTVGLVKLNRQLPSVTLQLMSIRRCGHSDSFFFMEVGRSAA TGPGELWMQADDSVVAQNIHETILEAMKALKELAEFRPRSKSQSASGSSASRPISVPGAR HLVGLPRRPRPDGRPGPGPCSACRLRTASEGDGSPCSPGPPFGRSHTGGCGGPPARTAKG LLPPAAASPGSPASLSSSSSGGGQSWGPVPPRPGFPPWSCSASTAGSPSDPGFMSLDEDG EDGNAAAYVSMERGGSPAGRPRTASLDEPGRRPYPEDYGRVEIGGRPHDAGYVAMTPGVA ARTADYVPMSPASVSAPQRIVRAGRRSPPEGSPEEEDEDDGGYMPMWSAARAALGPGGSP DGRRLPNGDYLHMSPSEPGPPPPPPPPGAAPCCCSYNSLPRSYKAPGPRPADRDQYVLMG ARAGPEHPLLQPLQQQQQQQHVWPQAQQPMPPRGRPGPPAASPPGPAPWPGSRPRAVRPT RLALETPRALPDPPPPPPPPPPPPEPRSPGEYVNIDFGEPSGRGPPASPSPSSLPSPGSW LSWGTPGTSAEGRRRSPLLDYMNVGFGGPAGGGGGGGGGGGSSPDGPASPDGASPSPPPG GDSPGPAAAGCARSPASALGRLSLRDRPDPQPAPVAPAKVVRADPQGGRRRHSSETFSAT ATVSPLSPPFAPRPKRHTSASVENVSLRKAAGPAPAPASHGPGLDYLAQRLKDAAKGKDV HEISRKASFPSCSKEATFSPSIPTACSASCTEKALLFDPMPSTTVTVVGGGKSHLAGQI NT seq 2880 nt NT seq  +upstreamnt  +downstreamnt atggccagtcctgcggcggcggcggcggcggcggcggcggcggcgggctgcaacctgaac aacaacaacaaccacccgtccggcgtgcgcaagtgcggctacctgcgcaagcagaagcac ggccacaagcgcttcttcgtgctgcggggcccggggcccccggcgcagcccgcccggctg gagtactacgacagcgagaagaagtggcggagcaaggccgcggcgcccaagcgggtgatc tcgctggactcctgcctcaacgtcaacaagcgggccgacgccaagcacaagtacctcatc gccctctacacccgcgacgagtacttcgccgtggcggccgacgacgagcgggagcaggac ggctggtaccgcgccctcaccgacctgctcagcgagggcaaggcggggcccgaggcctcg tccggctgctcgtcctgctcgtcgtcgtccctgcccagccccgccagccccgcgccggcc gtcgaggagcccccggccggggcggcctaccgggaggtgtggcaggtcaacctgaagccc aaggggctgggccacaccaagaacctgacgggcgtctaccggctgtgcctggcggcccgc acggtgggcctggtcaagctcaaccgccagctgccgtccgtcaccctgcagctgatgagc atccggcgctgcgggcactcggacagcttcttcttcatggaggtgggccgctcggccgcc accggccccggcgagctgtggatgcaggccgacgactcggtggtggcgcagaacatccac gagaccatcctggaggccatgaaggccctcaaggagctggccgagttccgcccccgcagc aagagccagtcggcgtcgggctcgtcggccagccgccccatcagcgtcccgggcgcccgg cacctggtgggtctgccccgccggccgcgccccgacgggcggccgggccccgggccctgc tcggcctgccgcctgcggacggccagcgagggggacggctccccctgcagccccgggccc ccgttcggacgctcgcacaccggcggctgcgggggacccccggcccgcacggccaagggg ctgctgccgcctgccgccgccagcccgggcagccccgccagcctgtcgtcgtcgtcgtcg ggcggcgggcagagctgggggcccgtcccgccgcgccccggtttccccccgtggagctgc agcgcctcgacggccggctcgcccagcgacccgggcttcatgtcgctggacgaggacggg gaggacggcaacgccgccgcctatgtcagcatggagcgcgggggcagccccgccggacgc ccccgcaccgcctcgctggacgagccgggccgccgcccctaccccgaggactacggccgg gtggagatcggcggccggccccacgacgccggctacgtggccatgacccccggcgtggcc gcccggacggccgactacgtgcccatgagccccgccagcgtgtcggccccgcagcgcatc gtaagggccggacgacgctcgcccccggagggctccccggaggaggaggacgaggacgac ggcggctacatgcccatgtggagcgcggcccgggcggccttggggcccgggggcagcccc gatggccggcggctgcccaacggcgactacctgcacatgtcccccagcgagcccggcccg ccgccgccgccgccgccccccggggccgccccttgctgctgctcctacaactccctgccg cgctcctacaaggcgcccggcccccggcccgcggaccgggaccagtacgtgctcatgggg gcgcgggccggcccggagcaccccctcttgcagcccttgcagcagcagcagcagcagcag cacgtctggccgcaggctcagcaaccaatgcccccgcgagggcgtccgggaccgccggcg gcctcccccccgggcccggcgccctggccgggctcccgcccccgggccgtgcggcccacc cgcctggccctggagaccccccgggccctgcccgacccgccgccgccgccgccgccaccg ccaccgccgccggagccccggagcccgggcgagtacgtcaacatcgacttcggggagccg tcgggccgcggcccccccgcctcgccgtcgccgtcgtcgctgcccagcccggggtcgtgg ctgagctggggcacgccgggcaccagcgccgaaggccggcgccgctcgccgctgctggac tacatgaacgtgggcttcgggggtccggcggggggcggcggcggcggcggcggcgggggc ggctcgtcgcccgacggtcctgcctcccccgacggcgcctcgccctcgccgccgccaggg ggcgactccccgggcccggcggcggccggctgcgcgcgcagccccgcgtccgccctcggc cgcctcagcctgcgggaccggcccgaccctcagcccgcccccgtcgcccccgccaaggtc gtccgcgcagacccccagggcggacgccgccgacacagctccgagaccttctccgccacc gccactgtgagccccctctccccgcccttcgcgccccgacccaagcgccacacctccgcc tccgtggagaacgtctccctcaggaaggccgccgggcctgcccccgcccccgccagccac ggacccggactcgactacctggcccagcgcctcaaggacgccgccaagggcaaagatgtg catgaaatatccaggaaagcctctttcccttcatgctccaaggaggcgacgttttcaccg tcgatacctactgcttgtagtgcttcctgcaccgaaaaggcactgctgtttgacccaatg ccttcaaccaccgtgactgtagttggaggggggaaatctcatttggctggccagatctga

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