KEGG   Ovis aries (sheep): 100135450
Entry
100135450         CDS       T03117                                 
Symbol
SQSTM1
Name
(RefSeq) sequestosome-1
  KO
K14381  sequestosome 1
Organism
oas  Ovis aries (sheep)
Pathway
oas04137  Mitophagy - animal
oas04140  Autophagy - animal
oas04217  Necroptosis
oas04218  Cellular senescence
oas04380  Osteoclast differentiation
oas05014  Amyotrophic lateral sclerosis
oas05022  Pathways of neurodegeneration - multiple diseases
oas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100135450 (SQSTM1)
   04137 Mitophagy - animal
    100135450 (SQSTM1)
  09143 Cell growth and death
   04217 Necroptosis
    100135450 (SQSTM1)
   04218 Cellular senescence
    100135450 (SQSTM1)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100135450 (SQSTM1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100135450 (SQSTM1)
   05022 Pathways of neurodegeneration - multiple diseases
    100135450 (SQSTM1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100135450 (SQSTM1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oas04131]
    100135450 (SQSTM1)
   03029 Mitochondrial biogenesis [BR:oas03029]
    100135450 (SQSTM1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oas04147]
    100135450 (SQSTM1)
Membrane trafficking [BR:oas04131]
 Autophagy
  Mitophagy
   Cargo receptors
    100135450 (SQSTM1)
  Pexophagy
    100135450 (SQSTM1)
  Aggrephagy
    100135450 (SQSTM1)
  Xenophagy
    100135450 (SQSTM1)
  ER-phagy
   ER-phagy recepters
    100135450 (SQSTM1)
  Other autophagy associated proteins
   Midbophagy
    100135450 (SQSTM1)
Mitochondrial biogenesis [BR:oas03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    100135450 (SQSTM1)
Exosome [BR:oas04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   100135450 (SQSTM1)
SSDB
Motif
Pfam: UBA_5 PB1 ZZ
Other DBs
NCBI-GeneID: 100135450
NCBI-ProteinID: NP_001156515
UniProt: A0A6P9FQM3 C5ISA9
LinkDB
Position
5:complement(1195379..1281918)
AA seq 440 aa
MASLTVKAYLLGKEDAAREIRRFSFCFSPEPEAEAEAAPGPRPCERLLSRVAALFPVLRP
GGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDQRPPCAQEVPRN
MVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSACEGKGLHREHGKLAFPSPFGHCSEGFS
HSRWLRKLKHGHFGWPGWEMGPPGNWSPRPPQAGEAHPGPATESASGPSEDPSVNFLKNV
GESVAAALSPLGIEVDIDVEHGGKRSRLTPSSAGSSSTEEKCSSQPSSCCSDPSKPDRDV
EGTTQSLTEQMNKIALESGGQPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPE
SEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK
NYDIGAALDTIQYSKHPPPL
NT seq 1323 nt   +upstreamnt  +downstreamnt
atggcgtcgctcacggtgaaggcctaccttctgggcaaggaagacgcagcccgcgagatc
cgccgcttcagcttctgcttcagcccggagcccgaggccgaagccgaggccgcccctggc
ccccggccctgtgagcggctgctgagccgtgtggctgcgctctttcctgtgctccggccc
ggcggctttcaggcgcactaccgcgatgaggacggggacttggttgccttttccagtgac
gaggagctgacgatggctatgtcatatgtgaaggatgacatcttccgcatttacattaaa
gagaagaaggagtgccggcgggaccagcgccccccgtgtgctcaggaggtgccccgaaac
atggtgcaccccaacgtgatctgtgacggttgcaacgggcccgtggtggggacccgctac
aagtgcagcgtctgtcctgactatgacctgtgctccgcctgtgagggcaagggcctgcac
cgggagcacggcaagctggccttccccagcccctttgggcactgctctgagggcttctct
cacagccgctggctccggaagctgaaacatgggcactttgggtggcctggctgggagatg
ggcccaccggggaactggagcccacgtcctcctcaggcaggggaggcccaccctggccct
gccacggaatcagcctctggtccatcagaagatcccagtgtgaatttcctcaagaatgta
ggggagagtgtggcggctgccctcagccctctgggcattgaagtcgacattgatgtggag
catggaggcaagagaagccgcctgaccccctcctctgcaggcagctccagcacagaggag
aagtgcagctctcagccaagcagctgctgctctgaccccagcaagccagacagggacgtg
gagggcacaacacagtctctgacggagcaaatgaataagatcgccctggagtcggggggt
cagcctgaggaacagatggagtctgataactgttcaggaggagatgatgactggactcat
ctgtcttcaaaagaggtggacccgtctacaggtgaactccagtctctacagatgcctgaa
tctgaagggccaagctctctggatccttcccaggaaggacccacaggactgaaggaagct
gcattgtacccacatctgccaccagaagctgatccccggctgattgagtccctctcccag
atgctatccatggggttctctgatgaaggcggctggctcaccaggcttctgcagaccaag
aattacgacattggggctgccctggacaccatccagtattcaaaacacccaccacctttg
tga

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