Ovis aries (sheep): 100170327
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Entry
100170327 CDS
T03117
Symbol
FASN
Name
(RefSeq) fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00061
Fatty acid biosynthesis
oas01100
Metabolic pathways
oas01212
Fatty acid metabolism
oas04152
AMPK signaling pathway
oas04910
Insulin signaling pathway
oas04936
Alcoholic liver disease
Module
oas_M00082
Fatty acid biosynthesis, initiation
oas_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100170327 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100170327 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100170327 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100170327 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
oas01004
]
100170327 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
oas04147
]
100170327 (FASN)
Enzymes [BR:
oas01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
100170327 (FASN)
Lipid biosynthesis proteins [BR:
oas01004
]
Fatty acid synthase
Animal type
100170327 (FASN)
Exosome [BR:
oas04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
100170327 (FASN)
Exosomal proteins of breast milk
100170327 (FASN)
Exosomal proteins of colorectal cancer cells
100170327 (FASN)
Exosomal proteins of bladder cancer cells
100170327 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
KR
Thioesterase
Ketoacyl-synt_C
FAS_pseudo-KR
KAsynt_C_assoc
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
PP-binding
adh_short
Methyltransf_12
Methyltransf_23
Thiolase_N
PS-DH
DUF7080
Methyltransf_11
Methyltransf_31
AlaDh_PNT_C
Motif
Other DBs
NCBI-GeneID:
100170327
NCBI-ProteinID:
XP_027830105
LinkDB
All DBs
Position
11:50277419..50296144
Genome browser
AA seq
2514 aa
AA seq
DB search
MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
DASFFGVHPKQAHNMDPQLRLLLEVTYEAIVDAGINPASIRGTNTGVWVGVSGSEAAEAL
SRDPETLVGYSMVGCQRAMMANRLSFFFDFKGPSITLDTACSSSLLALQRAYQAIQRGEC
AMAIVGGINILLKPNTSLQFMRLGMLSSEGTCKSFDASGDGYCRAEAVMAVFLTKKSLAR
RVYATILNAGTNTDGCKKQGVTYPSGEAQEQLISSLYKPAGLDPETLEYIEAHGTGTKVG
DPEELNGIVQALCGSRQGPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
NPNPKIPALQDGRLQVVDRPLPVLGGIVGINSFGFGGSNVHVILQPNSQPPPPPGPHAAL
PRLLLASGRTLEGVQGLLELGLQHSQNLAFVSMLNDIAAPSPAAMPFHGYAVLGSQEGSQ
EVQQVPTSKRPLWFICSGMGTQWRGMGLSLMRLSSFRDSILRSDEAVKPLGLRVSQLLLS
TDNIFDDIVVSFVSLTAFQIALIDLLTSMGLRPDGIIGHSLGEVACAYADGCISQEEAIL
SAYWRGQCIKEANIPPGAMAAVGLTWEECKQRCPPGIVPACHNSIDTVTISGPQASMLEF
VKQLKQEGVFAKEVQTGGMAFHSYFMDAIAPTLLQQLKKVIREPRLRSPRWLSTSIPESQ
WQESLARTFSAEYNVNNLVSPVLFQEALWHVPENAVVLEIAPHALLQAILKRGLQPSCTI
IPLMKKDHRDNLEFFLSNVGQLYLTGIDVNPNGLFPPVEFPAPRGTPLISPHIKWDHSQT
WDVPAAEDFPSGSSSSSATVYKIDISPESPDHYLVDHCIDGRVLFPATGYLCLVWKTLAR
ALDQDMEHTPVVFEDVTLHQATLLPKTGTVLLEVRLLEASCTFEVSEKGSLIVSGKVYQW
EDPDPKLFDNRYGAEPATPVDPTTAIHLRCGDVYKELQLQGFNYGPNFQGILEASSEGNM
GQLLWKDNWVTFMDTMLQMSILAPGQRSLRLPTRITAIYIHPATHQQKLYTLQDGTQVAD
VVMNRCLDTTVAGGVYISRIHTSVAPRHQQEQPVPILEKFCFTPHVESGCLAGNLALQEE
LQLCVGLAQALQTKVAQQGIKMVVPGLDGTQAPQEAPQQGLPQLLATACQLQLNGNLQMG
MGQILAQERALLCDDPLLSGLLNSPALKACVDTALENMTSLKMKVVEVLAGDGQLYSRIP
ALLNTQPLLELDYIATDRHPQALEAAQAKLQQLNITQGQWDPSDPAPSNLGGANLVVCNY
ALASLGDPATAVGNMVAALKEGGFLLLHTLLRGHPLGETVTFLTCPEPQQGQRHLLSQDE
WESLFAGTSLHLVALKKSFYGSVLFLCRRLAPRDSPIFLPVEDTSFQWVDSLKNILADSS
SQPVWLMAVGCTTSGVVGLVNCLRKEPDGHRIRCVLVSNLNSTSPIPEIAPKSLELQKVL
QSDLVMNVYRDGAWGAFRHFPLEQDKPEEQTEHAFINVLTRGDLSSIRWVCSPLRHSQST
GPGVQLCTIYYASLNFRDIMLATGKLSPDAIPGNWASRNCMLGMEFSGRDASGKRVMGLV
PAEGLATSTLVPQSFLWDVPSNWTLEEAASVPVVYSTAYYALIVRGRMQPGETVLIHSGS
GGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQSRFPQLNETSFANSRDTSFEQHVLWHTA
GKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLD
ALFEENSTMWQEVSSLLKAGIREGVVQPLKRTVFPRTQVEDAFRYMAQGKHIGKVVIQVR
EEEQKAVLHGTKPTQMAALCKTFCPAHKSYVITGGLGGFGLELAHWLVERGAQKLVLTSR
SGIRTGYQARQVREWRRQGVQVLVSTRDVSSLDGTQRLITEAAQLGPVGGVFNLAVVLRD
AMLDNQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQTNYGFA
NSTMERICEKRQHDGLPGLAVQWGAIADVGILVELKGTNDKAIGGTLPQRITSCLEVLDL
FLNQPHPVLSSFVLAEKAASRGPSGSQQDLVKAVAHILGIRDLATINPDSSLSDLGLDSL
MGVEVRQTLERERNLTLSMREIRQLTIRKLQEISAQAGTADELTNSTHKLSSPAQSQTQL
NLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSTTVFHSLAAKLSIPTYGLQCTRAA
PLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQSAGPTNNSLFLF
DGSHTFVMAYTQSYRAKMNPGCEAEAEAEAMCFFMRQFMEAEHSRVLEALLPLGDLEARV
AATVELIVQRHAGLDRHALSFAARSFYHKLRAAEQYAPRATYHGNVTLLRAKMGGAYGEG
LGADYNLSQVCDGKVSVHIIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG
NT seq
7545 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgatcgctggcatgtccgggaagctgcccgagtcggagaacctggag
gagttttgggccaatctcattggcggcgtggacatggtgacagatgatgacaggcggtgg
aaggcgggactatatggcctgcctcggcggtcaggcaagctgaaggacctgtcccggttt
gacgcttccttcttcggtgtccaccccaagcaggcgcacaatatggacccccagctccgc
ttgctgctggaggtcacctacgaggccattgtggatgcaggcatcaacccagcttccatt
cgggggacaaacaccggtgtctgggtgggtgtgagtggctctgaggctgcagaggctctg
agccgagaccctgagaccctcgtaggctacagcatggtgggctgccagcgtgccatgatg
gccaaccgtctctccttcttctttgacttcaaagggcccagcattaccttggacacggcc
tgctcctccagcctgctggccctgcagagggcctaccaggccatccagagaggggagtgt
gccatggccatcgtgggcggcataaacatcctgttgaagcccaacacctcgctgcagttc
atgaggctgggcatgctcagctctgagggcacctgcaagtccttcgatgcatcaggggat
ggctactgccgcgcagaggctgtgatggccgtctttctgaccaagaagtccttggcccga
cgggtgtatgccaccatcctcaacgctggcaccaacacggatggctgcaaaaagcaaggc
gtcacgtacccctccggagaggcacaggagcagctcatcagctccctgtacaagccggcc
gggctggacccggagaccctggagtacattgaagcccatggcaccggtaccaaggtgggt
gaccccgaggagctaaatggcatcgtgcaagccctgtgtggcagccgccaaggccccctg
ctgattgggtccaccaagtcgaacatgggacacccggagcctgcctcagggctcgcggcg
ctggccaaggtgctgctgtccctggagcacgggctctgggcccccaacctgcacttccac
aacccaaaccccaagatcccagcgctgcaggatgggcggctgcaggtggtggaccggccc
ctgcccgtcctcgggggcatcgtgggcatcaactcctttggcttcggtggctccaacgtg
cacgtcatcctccagcccaactcccagccaccgccacctcctggcccacatgctgccctg
ccccgtctgctgctggccagtgggcgcaccctggagggtgtgcaaggtctgctggagcta
ggcctccagcacagccagaacctggccttcgtgagcatgctcaatgacatcgcggccccc
tccccagcagccatgcccttccatggctatgccgtgctgggcagccaggagggcagtcag
gaggtgcagcaggtgccaaccagcaagcgcccactctggttcatctgctccggtatgggc
acacagtggcgcgggatggggctgagcctcatgcgtctgagcagcttccgtgactccatc
ctgcgctcagatgaggccgtgaagcctctgggactgcgggtgtcacagctgctgctgagc
acagacaacatctttgacgacatcgtcgtctccttcgtgagcctcactgccttccagatt
gccctcatagacctgctgacctccatgggccttcggcccgacggcatcatcgggcactcc
ctgggtgaggtggcctgtgcctatgccgacggctgcatctctcaggaggaggccatcctc
tctgcctactggaggggtcagtgcatcaaggaggccaacatcccgcccggggccatggcg
gctgtaggcttgacctgggaggagtgtaagcagcgctgcccccctggcatcgtgcctgcc
tgccacaactccatcgacactgtgaccatctcaggacctcaggcctccatgttggagttc
gtgaagcagctgaagcaggagggcgtgttcgccaaggaggtgcagacgggcggcatggcg
ttccactcctatttcatggacgccatcgccccgacgctgcttcagcagctcaagaaggtg
atccgggagccccggctgcgttccccacgctggctcagcacttccatccccgagtcccag
tggcaggagagcctggcccgcaccttctcggccgagtacaatgtgaacaacctggtgagc
cccgtgctgttccaggaggcactgtggcacgtgcccgagaacgctgtggtgctggagatt
gcgccccatgccctgctgcaggccatcctgaagagaggcctccagcccagctgcaccatc
atccccctgatgaagaaggaccacagggacaacctagagttcttcctcagcaacgtaggc
cagctctacctgaccggcattgacgtcaaccccaacgggctgttcccacccgtggagttc
ccggctccccggggcacccccctcatctccccccacatcaagtgggaccacagccagacc
tgggatgtgcccgccgctgaggatttccccagcggctccagcagctcctctgccactgtc
tataagattgacatcagccccgagtcccctgaccactacctggtggaccactgcatcgac
ggtcgcgtcctcttcccggccactggctatctgtgcctggtctggaagacactggcccga
gccctggaccaggacatggagcacacacctgtagtattcgaggacgtgacgctgcaccag
gctaccctcctgccgaagacagggactgtgctcctggaagtgcggcttctggaagcctcc
tgcacctttgaggtgtctgagaaaggcagtctgatcgtgagcgggaaggtataccagtgg
gaagatcccgaccccaagctctttgacaaccggtatggcgcggaacctgcgacccccgtg
gaccccacaactgccatccacctccgctgtggtgacgtgtacaaggagctgcagctgcag
ggcttcaactacggccccaacttccagggcatcctcgaggccagctctgaaggcaacatg
ggccagctgctctggaaggacaactgggtgaccttcatggacaccatgctgcagatgtct
atcctggccccgggccagcgcagcctgcgcctgcccacacgcatcaccgccatctacatc
cacccggctacccaccagcagaagctgtacacgctgcaggacgggacacaagtggccgac
gtggtaatgaacaggtgtctggacaccacggtggccggcggtgtctacatctcaaggatc
cacacctcggtggccccccggcatcagcaggagcagccggtgcccatcctggagaagttc
tgcttcaccccacacgtggagagcgggtgcctggccgggaacctggcccttcaggaggag
ctgcagctgtgtgtggggctggcacaggcgctgcagaccaaggtggcccagcaggggata
aagatggtggttcctgggctggacggcacccaggctccccaggaggccccacagcaaggc
ctgccccagctgctggccaccgcctgccagctgcaactcaacgggaacctgcagatgggg
atgggccagatcctagcccaggagagagccctgctgtgtgacgacccgctgctcagtggg
ctcctcaactccccagcactgaaggcgtgcgtggacactgccctggagaacatgaccagc
ctcaagatgaaggtggtagaggtgctagctggtgacggccaactgtattcccgcatccct
gcactgctcaacactcagcccctgttggagctggactacatagccactgaccgccacccc
caggccctggaggctgcccaggccaagttgcagcagctcaacataacccagggccagtgg
gacccctcggacccggcccccagcaacctgggtggggccaacctcgtggtgtgcaactat
gccctagccagcctcggtgacccggccacggctgtcggcaacatggtggctgccctcaag
gagggaggcttcctgttgctgcacacgctgctcagaggacaccccttgggagagactgtc
accttcctcacctgccctgagccacagcagggccaacggcacctcctgagccaggatgag
tgggagagcctgtttgctggcacgtccctgcacctggtggccctgaagaagtccttctac
ggctcggtgctcttcctgtgtcgccggctggccccacgtgacagcccaatcttcctgcct
gtggaggataccagcttccagtgggttgactccctgaagaacatcctggccgattcctcc
tcccagcccgtgtggctcatggctgttggctgcaccacctcaggggttgtgggcttggtg
aactgtctccggaaagagcctgacgggcaccggattcggtgcgtcctggtgtctaacctt
aacagcacgtcccccatccctgagatagccccgaagtccttggagctgcagaaggtgctc
cagagtgacctggtgatgaacgtctaccgtgatggggcttggggagcattccgccacttc
ccactggaacaagacaagcccgaggagcagacggagcacgccttcataaatgtactcaca
cgaggggacctgtcttccatccgctgggtctgttcccctctgcgccacagccagtccacg
ggccctggcgtccagctctgcaccatctattacgcctccctcaacttccgcgacatcatg
ctggccacgggcaagctgtcccccgacgccatcccaggaaattgggcctctcggaactgc
atgctaggcatggagttctctggccgagatgccagcgggaagcgtgtgatggggctggta
cccgccgaaggcctggccacctccactctggtgcctcagagcttcctgtgggacgtgcct
tccaactggaccctcgaggaggccgcctcggtgcccgttgtctacagcacagcctactac
gcgctgattgtccgcgggcgcatgcaaccaggggagaccgtgctcattcactcgggttct
ggcggcgtaggccaggctgccatcgccattgccctcagcctgggctgccgcgtcttcact
actgtggggtcagccgaaaagcgggcatacctccagtccaggttcccccagctcaacgaa
accagctttgccaactcccgggacacatcctttgagcagcatgtcctgtggcacacagcc
gggaagggtgttgacctcgtcctcaactccctggcggaagagaagctgcaggccagtgtg
cggtgcctggcccagcatggtcgattcctggaaattggcaaatttgacctttccaacaac
caccctctgggcatggccatcttcctgaagaacgtgactttccacgggatcctactggac
gcactctttgaagaaaacagcaccatgtggcaggaagtgtcatcgctgctgaaggcgggc
atccgggagggtgtggtacagcctctcaagcgaacagtgttccccaggacccaggtggag
gacgccttccgctacatggcccagggcaaacacatcggcaaagtggtcattcaggtgcgt
gaggaagagcagaaggcagtgctgcacgggaccaaacccacccagatggcggccttgtgc
aagaccttctgcccagcccacaagagctacgtcatcactgggggcctgggtggctttggc
ctagagttggcccactggctcgtggagcgaggggcccagaagctggtgctgacctcccgc
tctgggatccgcacaggctaccaagccaggcaggtccgtgagtggagacgccagggtgtg
caggtcctggtgtccaccagagatgtcagctcactggatggcacccagaggcttatcact
gaggccgcccagcttgggcccgtaggaggcgtcttcaacctggccgtggtcctgagagac
gccatgctggataaccagacccctgagttcttccaggacgtcaacaagcccaagtacaat
ggcaccctgaacttggacagggtgacccgggaggcatgcccggagctggactacttcgtg
gtcttctcctcggtgagctgcgggcgtggcaatgccggccagaccaactatgggttcgcc
aactccaccatggagcgcatatgcgagaagcgtcagcacgacggcctcccaggcctcgcc
gtgcagtggggcgcaattgctgatgtgggcatcctcgtggagctgaagggcactaacgac
aaggccatcggcgggacactgccccagcgcatcacctcctgcctggaggtgctagacctc
ttcctgaaccagccccaccccgtcctgagcagctttgtgttggcagagaaggctgcgtcc
cgtggccccagcggcagccagcaggacctggtgaaggccgtggctcacatcctgggcatc
cgtgacttggccaccatcaacccggacagctcgctttcagaccttggcctcgactcactc
atgggtgtggaggtgcgccagacgctggagcgtgagcgcaacctgacgctgtccatgcgg
gaaatccggcagctcaccatccgcaagctgcaggagatttccgcacaggctggcacggct
gatgagctgacgaactccacacacaaattgagcagccctgcccagtcgcagacgcagctg
aacctgagcaccctgctggtgaaccccgagggcccgaccttgacacggctcaactcggtg
cagagctccgagcggcccctgttcctggtgcaccccatagagggctctaccaccgtgttc
cacagcctggccgccaagctcagcatccccacctatggcctacagtgtacaagagcggca
cccttggacagcatccagagcctggctgcctactacatcgagtgcatcaggcaggtgcag
ccagaggggccctaccgcatcgccggctactcttacggggcctgcgtggctttcgagatg
tgctcacagctgcaggcccagcagagcgccggccccacgaacaacagcctcttcctgttt
gacggctcccacacattcgtgatggcctacactcagagctaccgggccaagatgaacccc
ggctgcgaggcagaggccgaggccgaggccatgtgcttcttcatgcggcagttcatggaa
gcggagcacagcagggtgctggaggccctcctgcccctcggggatctggaggcgcgtgtg
gcagccaccgtcgagctgatcgtgcagaggcacgcaggcctggaccggcacgcgctcagc
tttgctgcgcgctctttctaccacaagctgcgcgccgcggagcagtacgcgccgcgggcc
acctaccacggcaacgtgacgctgctgcgcgccaagatgggcggtgcctacggggagggc
ctgggtgccgactacaatctgtcccaggtgtgcgacggcaaggtgtctgtgcacatcatc
gagggcgaccaccgcacgctgctggagggcagcggcctggagtccatccttagtattatt
cacagctccctggccgagccgcgcgttagcgtgcgggagggctag
DBGET
integrated database retrieval system
