Ovis aries (sheep): 100216439 Help Entry 100216439         CDS       T03117                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism oas  Ovis aries (sheep) Pathway oas04064   NF-kappa B signaling pathway oas04380   Osteoclast differentiation oas04650   Natural killer cell mediated cytotoxicity oas04658   Th1 and Th2 cell differentiation oas04659   Th17 cell differentiation oas04660   T cell receptor signaling pathway oas05135   Yersinia infection oas05166   Human T-cell leukemia virus 1 infection oas05235   PD-L1 expression and PD-1 checkpoint pathway in cancer oas05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:oas00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     100216439 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100216439 (LCK)    04660 T cell receptor signaling pathway     100216439 (LCK)    04658 Th1 and Th2 cell differentiation     100216439 (LCK)    04659 Th17 cell differentiation     100216439 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     100216439 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100216439 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100216439 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     100216439 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     100216439 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oas01001]     100216439 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:oas03036]     100216439 (LCK) Enzymes [BR:oas01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100216439 (LCK) Protein kinases [BR:oas01001]  Non-receptor tyrosine kinases   SRC family    100216439 (LCK) Chromosome and associated proteins [BR:oas03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     100216439 (LCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 Haspin_kinase Kdo Motif Other DBs NCBI-GeneID:  100216439 NCBI-ProteinID:  NP_001135987 EnsemblRapid:  ENSOARG00020021346 UniProt:  B7U173 LinkDB All DBs Position 2:complement(235268263..235288875) Genome browser AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASP LQDNLVIALHSYVPSHDGDLGFEKDEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKH YKIRNLDKGGFYISPRVTFPGLHELVRHYMNTSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKER REDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaacccagaagatgactggatggaaaacatcgatgtttgt gaaaactgccactaccccatagtcccactggatggcaagaccacgctgcccatgcggaat ggctctgaagtgcgtgatccactggtcacctacgagggatccaaccccccagcttctcca ctgcaagacaacctggttatcgccctgcacagctatgtgccttctcacgacggagacctg ggcttcgagaaggatgaacagctccgcatcctggagcagaacggcgagtggtggaaggcg cagtccctgaccaccggccaggaaggtttcatccccttcaactttgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagaccctgagccgcaaggacgcggagaggcag ctcctggcgccggggaacacgcacggctctttcctgatccgggagagcgagagcactgcg ggatcgttttcactgtcggtccgggacttcgaccagacccagggagaagtggtgaaacat tacaagatacggaacctggacaaaggcggcttctacatctcgccccgcgtcacttttccc ggcttgcacgagctggtccgccattacatgaatacttcggacgggctgtgcacacggttg agccgcccctgccagacccagaagccccagaagccgtggtgggaggatgagtgggaggtt cccagggagactctgaagctggtggagcggctgggggctggccagttcggagaggtgtgg atggggtactacaacgggcacacgaaggtggcagtcaagagcctgaagcagggcagcatg tcccccgatgccttcctggccgaagccaacctcatgaagcagctgcaacaccagcggctg gtccggctctacgcggtggtcacccaggagccgatctacatcatcacggaatatatggag aacggaagcctggtggattttctcaagacttccgaaggcatcaagctgactatcaacaaa ctcttggacatggcagcccaaattgcagagggtatggcattcattgaagagcggaattat atccaccgtgacttgagggctgccaacatcctggtgtcccatagcctgagctgcaagatc gcagactttggtctagcacgcctcattgaggacaacgagtacacagcccgggagggtgcc aagtttcccattaagtggacagcaccagaagccattaactatgggacattcaccatcaag tcggatgtgtggtctttcgggatcctgctgacggagattgtcactcatggtcgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggta agacctgacaactgcccggaggagttgtaccagcttatgatgctgtgctggaaggagcgc cgggaggaccggcccacctttgactacctgcgcagcgtgttggaggacttcttcacagcc acggagggccagtaccaaccccaaccctga

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