KEGG   Ovis aries (sheep): 101102131
Entry
101102131         CDS       T03117                                 
Symbol
PINK1
Name
(RefSeq) serine/threonine-protein kinase PINK1, mitochondrial isoform X1
  KO
K05688  PTEN induced putative kinase 1 [EC:2.7.11.1]
Organism
oas  Ovis aries (sheep)
Pathway
oas04137  Mitophagy - animal
oas05012  Parkinson disease
oas05014  Amyotrophic lateral sclerosis
oas05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:oas00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    101102131 (PINK1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    101102131 (PINK1)
   05014 Amyotrophic lateral sclerosis
    101102131 (PINK1)
   05022 Pathways of neurodegeneration - multiple diseases
    101102131 (PINK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oas01001]
    101102131 (PINK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oas04131]
    101102131 (PINK1)
   03029 Mitochondrial biogenesis [BR:oas03029]
    101102131 (PINK1)
Enzymes [BR:oas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101102131 (PINK1)
Protein kinases [BR:oas01001]
 Serine/threonine kinases: Other
  NKF2 family
   101102131 (PINK1)
Membrane trafficking [BR:oas04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    101102131 (PINK1)
Mitochondrial biogenesis [BR:oas03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    101102131 (PINK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like APH
Other DBs
NCBI-GeneID: 101102131
NCBI-ProteinID: XP_014949215
LinkDB
Position
2:complement(245716754..245733917)
AA seq 587 aa
MAVRQALGRGLQLGRALLLRFTAKPGPAYGWGRPERPGPAAGWGRGERPGPAAGPGTEPC
RLGLGLPGRYRFFRQSVAGLAERLQRQFVVRARGGAGPRGRAVFLAFGLGLGLIEEKQAE
GRRAASACEEIQAVFTQKNKLLPDPLDTRRWQGFRLEEYLIGQSIGKGCSAAVYEAAMPV
LPRNLEEAESLGQLLPGKGPEILPRGEEALAPRAPAFPLAIKMMWNISAGSSSEAIFSAM
SQELVPASRVAVAGEYGAATPGRPKGGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPD
VLPPCLHPAGLGHGRTLFLVMKNYPCTLRQYLRGNTPSPRLATVMTLQLLEAVDHLVQQG
VAHRDLKSDNILVELDADGCPWLVITDFGCCLADERVGLQLPFTSWYVDRGGNGCLMAPE
VSTACPGPRAVIDYSKADAWAVGALAYEIFGLPNPFYGQGRAHLESRSYQEAQLPALPEW
VPWDVRCLVRSLLQREACKRPSARVAANVLHLSLWGEHTLALKNLKPDEMIGWLLQQSAA
TLLANRLTENCVETKMKMLFLANLEYEALSQAALLLDSWRAAPRQLL
NT seq 1764 nt   +upstreamnt  +downstreamnt
atggcggtgcgacaagcgctgggccgaggcctgcagctgggccgagcgctgctcctacgc
ttcacggccaagcccggcccggcctacggctggggccggccggagcggcccggccccgcg
gcgggctggggtcgcggagagcgcccgggcccggccgcgggacccggcacggagccgtgc
aggctcgggctcgggcttcccggccgctaccgcttcttccgccagtcggtggccgggctg
gcggagcggctccagcggcagttcgtggtgcgagcccggggcggtgcgggccctcgcggc
cgcgctgtctttctggccttcgggctggggctgggcctcatcgaggagaagcaagcggag
ggccggcgggccgcctcagcctgtgaggagattcaggcagttttcacccagaaaaacaag
ctgctcccggacccactggacacccgacgctggcagggtttccggctggaggagtatctg
atcgggcagtccattggcaagggctgcagtgccgccgtctatgaggccgccatgcctgtg
ttgccccggaacctggaggaggcagagagcctgggccagcttcttccagggaagggccca
gagatccttccacggggagaggaggcgctggccccgcgggccccggccttccccttggcc
atcaagatgatgtggaacatctcggcaggctcatccagcgaagccatctttagcgcaatg
agccaggagctggtcccagccagtcgagtggccgtggccggggagtatggagcggccact
cctggaagacccaagggaggtcccaagcagctggccccgcatcccaacatcatccgggtc
ttgcgagccttcacctcgtcggtgccgctgctgccaggagccctggtcgactacccagat
gtgctgcccccctgtcttcaccccgcaggcctgggccacgggcggactctcttccttgtc
atgaagaactacccctgtaccctgcgccagtaccttcgcgggaacaccccaagcccccgg
ctggccactgtgatgactctgcagctcttggaagcagtggatcacctggtccagcagggc
gtcgcgcacagagacctgaagtccgacaacatccttgtggaactggacgcagacggctgc
ccctggttggtgatcacagactttggctgctgcttggctgatgagcgcgtcggcctgcag
ttgcctttcaccagctggtacgtggaccgcggcggaaatggctgcctgatggctcctgag
gtgtccacggcctgccctggccccagggcagtgatcgactacagcaaggcggatgcctgg
gcggtgggcgcactcgcctatgaaatctttgggctccccaatcccttttatggccagggc
agggcccaccttgaaagccgcagttaccaggaggctcagctgccagcactgcccgagtgg
gtgccgtgggacgtgaggtgcctggtgaggtcgctgctgcagcgggaggcttgcaagagg
ccatccgcccgagtggctgctaacgtgcttcacttaagcctctggggtgaacacacgctc
gccctgaagaacctgaaaccagacgagatgattggctggctcctccaacaatcggccgcc
actctgctggccaacagactgacggagaactgtgtggaaacgaaaatgaagatgctgttt
ctggccaacctggagtatgaagcgctgagccaggcggccctcctcctcgactcctggagg
gcggccccgagacagctgctgtag

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