Ovis aries (sheep): 101107334 Help Entry 101107334         CDS       T03117                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism oas  Ovis aries (sheep) Pathway oas01524   Platinum drug resistance oas04115   p53 signaling pathway oas04210   Apoptosis oas04215   Apoptosis - multiple species oas04217   Necroptosis oas04620   Toll-like receptor signaling pathway oas04621   NOD-like receptor signaling pathway oas04622   RIG-I-like receptor signaling pathway oas04623   Cytosolic DNA-sensing pathway oas04625   C-type lectin receptor signaling pathway oas04657   IL-17 signaling pathway oas04668   TNF signaling pathway oas04932   Non-alcoholic fatty liver disease oas04936   Alcoholic liver disease oas05010   Alzheimer disease oas05016   Huntington disease oas05022   Pathways of neurodegeneration - multiple diseases oas05132   Salmonella infection oas05134   Legionellosis oas05142   Chagas disease oas05145   Toxoplasmosis oas05152   Tuberculosis oas05160   Hepatitis C oas05161   Hepatitis B oas05162   Measles oas05163   Human cytomegalovirus infection oas05164   Influenza A oas05165   Human papillomavirus infection oas05167   Kaposi sarcoma-associated herpesvirus infection oas05168   Herpes simplex virus 1 infection oas05169   Epstein-Barr virus infection oas05170   Human immunodeficiency virus 1 infection oas05200   Pathways in cancer oas05203   Viral carcinogenesis oas05416   Viral myocarditis oas05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:oas00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     101107334 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     101107334 (CASP8)    04215 Apoptosis - multiple species     101107334 (CASP8)    04217 Necroptosis     101107334 (CASP8)    04115 p53 signaling pathway     101107334 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101107334 (CASP8)    04621 NOD-like receptor signaling pathway     101107334 (CASP8)    04622 RIG-I-like receptor signaling pathway     101107334 (CASP8)    04623 Cytosolic DNA-sensing pathway     101107334 (CASP8)    04625 C-type lectin receptor signaling pathway     101107334 (CASP8)    04657 IL-17 signaling pathway     101107334 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101107334 (CASP8)    05203 Viral carcinogenesis     101107334 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101107334 (CASP8)    05161 Hepatitis B     101107334 (CASP8)    05160 Hepatitis C     101107334 (CASP8)    05164 Influenza A     101107334 (CASP8)    05162 Measles     101107334 (CASP8)    05168 Herpes simplex virus 1 infection     101107334 (CASP8)    05163 Human cytomegalovirus infection     101107334 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     101107334 (CASP8)    05169 Epstein-Barr virus infection     101107334 (CASP8)    05165 Human papillomavirus infection     101107334 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     101107334 (CASP8)    05134 Legionellosis     101107334 (CASP8)    05152 Tuberculosis     101107334 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101107334 (CASP8)    05142 Chagas disease     101107334 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     101107334 (CASP8)    05016 Huntington disease     101107334 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     101107334 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101107334 (CASP8)    05416 Viral myocarditis     101107334 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101107334 (CASP8)    04932 Non-alcoholic fatty liver disease     101107334 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101107334 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:oas01002]     101107334 (CASP8) Enzymes [BR:oas01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      101107334 (CASP8) Peptidases and inhibitors [BR:oas01002]  Cysteine peptidases   Family C14: caspase family    101107334 (CASP8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED ROXA-like_wH ERM_C AIG1 PYRIN Motif Other DBs NCBI-GeneID:  101107334 NCBI-ProteinID:  XP_011997867 UniProt:  A0A6P3T9A7 A0A6P3TJN8 LinkDB All DBs Position 2:203617067..203641002 Genome browser AA seq 488 aa AA seqDB search MDLTQCLYKIGEQLGSDDLAALKFLSRDHIPYRKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFQVNRLDLLLNYLDTSEEEMKRELQIPGRAQISAYRILLFQISEDVNKVELKDF KFFLSQEIAKCKLDDDMTLLDIFVEMEKRTILGENNLDTLKRICEQVNKSLLKKIYDYEE LRKDSERIMRLERDPDEFSNDMSQSLPEEGSSEMLAMSDSPGEQGSELQTSDTVYRMTSK PRGYCLIFNNYDFSIAREQVPELHSLKDRNGTHLDAEALDKTFRELHFEIVHYRDQTAKG ICEVLKSYQKKDHKTKDCFICCILTHGNKGTIYGSDGQEAPIYELTSYFTGSKCPSLVGK PKIFFIQACQGDKYQRGIAVETDSEQREAYLEADSSPQKRYIPDEADFLLGMATVNNCVS YRSIVKGTWYIQSLCQNLRERCPRGEDILTILTKVNFEVSKKDDKQNMGKQMPQPTFTLR KKLFFPLN NT seq 1467 nt NT seq  +upstreamnt  +downstreamnt atggatctcacccaatgtctctataaaattggagagcagctgggcagtgacgacctggct gccctcaagttcctaagccgggaccacatcccatataggaagcaggaacccattaaggat gccttgatgctattccagaggctccaagaaaagagaatgttggaggaaagcaatctgtcc ttcttgaaggagctgcttttccaagtgaatagactggatctgctgcttaactacttggac accagcgaggaagagatgaagagggagcttcagatacctggcagggcccagatctctgcc tacaggatcctgcttttccagatttcagaagatgtgaacaaagtggaattgaaggacttt aagttttttttgagccaggagattgccaaatgtaagctggatgatgacatgactttgctt gatattttcgtggagatggagaagaggaccatcctaggggaaaataacttggacaccctg aaaagaatctgtgagcaggtcaacaagagcttgctgaagaaaatctatgattatgaagaa ttaagaaaagattcagagagaataatgagacttgaaagagatccagatgaattttcaaat gatatgtcacaatcgcttccagaggagggctcctctgagatgctggccatgtcagactct ccaggagaacagggcagtgagttgcagacatccgacacagtttaccgaatgacaagcaaa cctcggggatactgtttgatctttaacaattatgattttagcatagcacgggagcaggtg cccgaacttcacagccttaaggataggaatggaacacacttggatgcagaggctttggac aagacctttcgtgaacttcattttgagatagtgcactacagagaccaaacagcaaaggga atctgtgaggttctgaaatcctaccagaagaaggaccacaaaaccaaagactgcttcatc tgctgcatccttacccatggaaacaagggcaccatctatggctccgatgggcaagaagcc cccatctatgagctgacctcctacttcactggatcaaaatgcccttcccttgtcggcaaa cccaaaatcttttttattcaggcttgtcaaggggataagtaccagagaggaatagctgtt gagaccgactcagaacagagggaagcctatttagaagcggattcgtcacctcagaagaga tatatcccagatgaggctgactttctgctggggatggccactgtgaacaactgtgtttcc taccgaagcatcgtgaaggggacctggtatatccaatcgctttgtcagaacctgagagaa agatgtcctaggggtgaagacattctgaccatcctaaccaaggtgaacttcgaagtaagc aaaaaggatgacaagcaaaacatgggcaaacagatgccgcaacctactttcacactgcga aaaaaactcttctttcctcttaattga

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