Ovis aries (sheep): 101107690 Help Entry 101107690         CDS       T03117                                  Symbol HK2 Name (RefSeq) hexokinase-2 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism oas  Ovis aries (sheep) Pathway oas00010   Glycolysis / Gluconeogenesis oas00051   Fructose and mannose metabolism oas00052   Galactose metabolism oas00500   Starch and sucrose metabolism oas00520   Amino sugar and nucleotide sugar metabolism oas00524   Neomycin, kanamycin and gentamicin biosynthesis oas01100   Metabolic pathways oas01200   Carbon metabolism oas01250   Biosynthesis of nucleotide sugars oas04066   HIF-1 signaling pathway oas04910   Insulin signaling pathway oas04930   Type II diabetes mellitus oas04973   Carbohydrate digestion and absorption oas05230   Central carbon metabolism in cancer Module oas_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate oas_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:oas00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101107690 (HK2)    00051 Fructose and mannose metabolism     101107690 (HK2)    00052 Galactose metabolism     101107690 (HK2)    00500 Starch and sucrose metabolism     101107690 (HK2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     101107690 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     101107690 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     101107690 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101107690 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     101107690 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     101107690 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101107690 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oas04131]     101107690 (HK2) Enzymes [BR:oas01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      101107690 (HK2) Membrane trafficking [BR:oas04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     101107690 (HK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  101107690 NCBI-ProteinID:  XP_014949962 LinkDB All DBs Position 3:96669457..96737497 Genome browser AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDDTLLEIAKRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVRVTDNGLQKVEMENQIYAIPEDIMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCLQTKLDESFLVSWTKGFKSSGV EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDTVEGDEGRMCINMEWGAFGDDGALDDIRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKLSPELLATGHFETKDVSDIEGEKDGIRKAREILVRLG LNPTDEDCVATHRVCQIVSTRSASLCAATLAAVLRRIKENKGVDRLRSTVGVDGSVYKKH PQFAKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLS REQLLEVKKRMKIEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVMLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD LRTEFDAAVDELSLNPGRQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgattgcctcacatctgctcgcctacttctttacggagctcaaccacgaccaagtgcag aaggttgaccagtatctctaccacatgcgtctttctgatgatactcttctggagattgct aagcggtttcgtaaggagatggagaaagggcttggagccaccactcaccccaccgcttca gtaaaaatgctgcctacttttgtgaggtctactccagacgggacagaacatggagagttc ctggctctggaccttggagggaccaacttccgtgtgctttgggtaagagtaacagacaat ggactccagaaggttgagatggagaaccagatctatgccatccccgaggacatcatgcga ggcagtggcacccagctgtttgatcacattgctgaatgcctggccaacttcatggataag ctacaaatcaaagataagaagctccctttgggttttaccttctccttcccctgcctccaa acaaaactagacgagagtttcctggtctcatggaccaaggggttcaagtccagtggtgtg gaagggaaagatgtggttactctgatccggaaggccatccagaggagaggggactttgat attgatattgtggctgtagtgaatgataccgttgggaccatgatgacctgtggctatgat gatcagaactgtgagattggtctcattgtgggcacgggcagcaacgcttgctacatggaa gagatgcgccacattgacacggtggaaggcgatgagggccggatgtgtatcaatatggag tggggggcctttggggatgacggcgcgcttgatgacatccgtacggagtttgatcaggag atcgacatgggctctctgaaccccgggaagcaactatttgagaagatgatcagtggaatg tacatgggggaactggtgaggcttatcctggtgaagatggccaaggaggagctgctcttt ggggggaagctcagccctgaacttcttgccacaggccattttgagaccaaagatgtttca gatattgaaggggagaaggatggcatccggaaggcccgtgagatcctggtgcggctgggg ctgaacccgacggatgaggactgtgtggctactcatcgggtctgccagatcgtgtccaca cgctcggccagcctgtgtgcggctacgctggcggccgtgctgcggcgcatcaaggagaac aaaggcgtggaccggctgcgctccaccgtcggggttgatggctccgtctacaagaagcac cctcagtttgccaagcgtcttcacaagaccgtgcggcgcctggtgcctgactgtgatgtc cgcttcctccgctctgaggatggcagtggcaagggggcagccatggtgacggcagtggcc tatcggctggccgatcagcaccgagcccgccagaagaccctggagtctctgaagctgagc cgtgagcagctgctggaggtcaagaagaggatgaagatagaaatggagcgaggtctgagc aaggagactcacgccattgctcctgtcaagatgctgcccacctacgtgtgtgccacccct gacggcacagagaaaggagacttcctggccttggaccttgggggcaccaatttccgggtc ctgctggtgcgtgtgcggaacgggaagcgccgcggggtggagatgcacaacaagatctac tcgatcccgcaggaggtcatgcacggcacaggggacgagctctttgaccacatcgtccag tgcattgcggacttcctggagtacatgggcatgaagggtgtgtccctgcctctaggtttc acgttctccttcccctgccagcagaacagcctagacgagagcatcctcctgaagtggact aaaggcttcaaggcgtctggctgcgagggtgaggacgtagttatgctgctgaaggaagcc atccaccggcgagaggagtttgacctggacgtggttgccgtggtgaacgatacagttggg actatgatgacctgtggctatgaagaccctcactgtgaagtcggcctcattgttggcaca ggcagcaatgcctgctacatggaggagatgcggaatgttgagctggtggaaggggaagag gggcggatgtgtgtcaacatggagtggggggccttcggggacaacggatgcctcgatgac ttgcgcacagaatttgatgcagctgtggatgaactttcccttaaccctggcagacagagg tttgagaaaatgatcagcggcatgtacttgggcgagattgttcgtaacatcctcatcgat ttcaccaagcgtgggctgcttttccgtggccgcatctcagagcggctcaagacaagggga atctttgaaaccaagttcctgtctcagattgagagtgactgcctggccctgctgcaggtc cgcgccatcctgcaccacttagggctcgagagcacctgcgatgacagcatcatcgtcaag gaggtgtgcaccgtggtggctcgacgggcagcccagctctgtggcgcaggcatggctgct gtagtggacaaaatacgagaaaaccgtgggctggacaccctcaaagtgacagtgggtgtg gacgggaccctctacaagctacatcctcactttgccaaagtcatgcatgagacggtgaag gacttggctccaaaatgtgatgtgtccttcctggagtcagaagatggcagtgggaagggg gcagctctcatcactgctgtggcctgccgcatccgagaggctggacaacggtag

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