Ovis aries (sheep): 101108127
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Entry
101108127 CDS
T03117
Symbol
ALDH7A1
Name
(RefSeq) alpha-aminoadipic semialdehyde dehydrogenase isoform X2
KO
K14085
aldehyde dehydrogenase family 7 member A1 [EC:
1.2.1.31
1.2.1.8
1.2.1.3
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00010
Glycolysis / Gluconeogenesis
oas00053
Ascorbate and aldarate metabolism
oas00071
Fatty acid degradation
oas00260
Glycine, serine and threonine metabolism
oas00280
Valine, leucine and isoleucine degradation
oas00310
Lysine degradation
oas00330
Arginine and proline metabolism
oas00340
Histidine metabolism
oas00380
Tryptophan metabolism
oas00410
beta-Alanine metabolism
oas00561
Glycerolipid metabolism
oas00620
Pyruvate metabolism
oas00670
One carbon pool by folate
oas01100
Metabolic pathways
oas04936
Alcoholic liver disease
Module
oas_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
oas_M00135
GABA biosynthesis, eukaryotes, putrescine => GABA
oas_M00555
Betaine biosynthesis, choline => betaine
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101108127 (ALDH7A1)
00053 Ascorbate and aldarate metabolism
101108127 (ALDH7A1)
00620 Pyruvate metabolism
101108127 (ALDH7A1)
09103 Lipid metabolism
00071 Fatty acid degradation
101108127 (ALDH7A1)
00561 Glycerolipid metabolism
101108127 (ALDH7A1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
101108127 (ALDH7A1)
00280 Valine, leucine and isoleucine degradation
101108127 (ALDH7A1)
00310 Lysine degradation
101108127 (ALDH7A1)
00330 Arginine and proline metabolism
101108127 (ALDH7A1)
00340 Histidine metabolism
101108127 (ALDH7A1)
00380 Tryptophan metabolism
101108127 (ALDH7A1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
101108127 (ALDH7A1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101108127 (ALDH7A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101108127 (ALDH7A1)
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.3 aldehyde dehydrogenase (NAD+)
101108127 (ALDH7A1)
1.2.1.8 betaine-aldehyde dehydrogenase
101108127 (ALDH7A1)
1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
101108127 (ALDH7A1)
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-GeneID:
101108127
NCBI-ProteinID:
XP_004008714
UniProt:
W5QAE8
LinkDB
All DBs
Position
5:25016887..25113434
Genome browser
AA seq
539 aa
AA seq
DB search
MWRVPGLLCVRVARKSKFSGPWTGPAAFMSTLLINQPQYAWLKELGLREENDGVYNGSWG
GRGEVITTYCPANNEPIARVRQASMADYEETVEKAREAWSIWADIPAPKRGEIVRQIGDA
LREKIQVLGSLVSLEMGKILVEGVGEVQEYVDVCDYAVGLSRMIGGPILPSERPGHALIE
QWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNACLWKGAPTTSLISVAVTKIIAKVLED
NKLPGAICSLTCGGADVGTAMAKDERVDLLSFTGSTQVGKQVALMVQERFGRSLLELGGN
NAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFLHESIHDEVVNRLKKAYAQIRVG
NPWDSNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLEHD
ASIVHTETFAPILYVFKFKNEDEVFAWNNEVKQGLSSSIFTKDMGRIFRWLGPKGSDCGI
VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgtggcgcgttcccggtctgctctgcgtgcgcgttgcaaggaagagcaagttctccgga
ccttggaccgggcctgccgccttcatgtccactctgctcatcaatcagcctcagtatgct
tggctgaaggagctggggctccgcgaggaaaacgacggcgtgtataatggaagctgggga
ggccggggagaggtaatcaccacctattgtcctgctaacaatgagcccattgccagagtc
agacaggccagcatggctgactatgaagaaactgtagagaaagcaagagaagcatggagc
atctgggcagatattcctgctccaaagcgaggagaaatcgtgagacagattggtgatgcc
ttgcgggagaagatccaagtgctaggaagcttggtgtctttggagatggggaagatcttg
gtggaaggtgtgggagaagttcaggaatacgtggatgtttgtgattatgctgttggctta
tctcggatgattgggggacccatcctgccttctgaaagacctggccatgctctcattgaa
cagtggaatcctgtaggcctggttggaatcatcactgctttcaacttccctgtggccgtg
tatggctggaacaacgccattgccatgatctgtgggaacgcttgcctttggaaaggagct
cctacaacttccctcattagtgtagctgtcacaaagataatagccaaagttctggaggac
aacaagctgcctggtgcaatttgttccttgacttgtggtggagcagatgtcggcacagca
atggccaaggatgagcgggtggacctgctgtccttcaccgggagcactcaggtgggaaaa
caggtggcgctcatggtacaggagaggtttgggagaagtttattagaacttggaggaaac
aatgccattatagcttttgaggacgcggacctcagcttagtcgtcccctcagctctcttt
gcagccgtggggacagccggccagaggtgtaccacggcgaggcgcctgttcttacatgaa
agcatccatgatgaagttgtcaatagacttaaaaaggcctatgcacagatccgtgttggg
aacccttgggactctaacgttctctatgggccactccacaccaaacaggcagtaagcatg
tttcttggagcagtggaagaagcaaagaaggaaggtggcaccgttgtctatggtggcaag
gttatggatcgccctggaaattacgtagaaccgacaatcgtgacaggtcttgagcatgac
gcatccattgtacacacagagacttttgccccgattctttatgtctttaaattcaagaat
gaagatgaggtctttgcatggaacaatgaagtcaaacagggactttcaagtagcatcttt
accaaggatatgggcagaatctttcgctggcttggaccaaaaggatcagattgtggcatt
gtaaacgtcaacattccaacgagtggggctgagattggaggtgcatttggaggagagaag
cacactggcggtggcagggagtcgggcagtgatgcctggaagcagtacatgagaagatct
acttgtaccatcaactacagtaaggaccttcctctggcccaaggaatcaagtttcagtaa
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