Ovis aries (sheep): 101111590
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Entry
101111590 CDS
T03117
Symbol
HMGCS2
Name
(RefSeq) hydroxymethylglutaryl-CoA synthase, mitochondrial
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00280
Valine, leucine and isoleucine degradation
oas00650
Butanoate metabolism
oas00900
Terpenoid backbone biosynthesis
oas01100
Metabolic pathways
oas03320
PPAR signaling pathway
Module
oas_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
101111590 (HMGCS2)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
101111590 (HMGCS2)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
101111590 (HMGCS2)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
101111590 (HMGCS2)
Enzymes [BR:
oas01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
101111590 (HMGCS2)
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GFIT
Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
ACP_syn_III
Motif
Other DBs
NCBI-GeneID:
101111590
NCBI-ProteinID:
XP_004002439
UniProt:
W5QGT9
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Position
1:complement(97112935..97137264)
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AA seq
508 aa
AA seq
DB search
MQRLLTPVRRVLQVKRVMQEASLLPARLLPAAHPSFSTVPAVPLAKTDTWPKDVGILAME
VYFPAQYVDQTELEKFNKVEAGRYTVGLGQTQMGFCSVQEDVNSLCLTVVQQLMERTQLP
WDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWM
ESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLRGTHMENVYD
FYKPDVTSEYPLVDGKLSIQCYLRALDKCYAFYRQKIEKQWKQAGIDRPFTLDDVQYMIF
HTPFCKLVQKSLARLMFNDFLLASGDTQTGVYKGLEAFRGLKLEDTYTNKEVDKAFLKAS
LNMFNKKTKNSLYLSTYNGNMYTSSLYGCLASLLAHHSAQDLAGSRIGAFSYGSGLAASF
FSFRVSQDASPGSPLEKLVSSTSDLQKRLASRKRVSPEEFTEIMNQREQYYHKMNFSPPG
DKNSLFPGTWYLERVDELYRRKYARRPV
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgcagcggctgttgactccagtgaggcgggtgttgcaagtgaagagagtgatgcaagaa
gcttccctcctgcctgcccgccttctccccgcagcccaccccagtttttctacagttccg
gctgtccccttggccaaaacagatacttggccaaaggatgtgggtattcttgccatggag
gtctactttccagcccaatatgtggaccaaacagagctggagaagttcaacaaggtggag
gcagggaggtacaccgtgggcttgggccagacccagatgggcttctgctcagtccaggag
gatgtcaactccctgtgcctgacggtggtgcaacagctgatggagcgcacgcagctcccc
tgggactctgtgggccgcctggaagtgggcactgagaccatcatcgataagtccaaggct
gtcaaaacagtgctcatggagctcttccaggattcaggcaacactgacattgaaggcata
gataccaccaatgcctgctacggtggcactgcctccctcttcaatgctgctaactggatg
gaatccagctcctgggatggtcgctacgcactggtggtctgtggggacatcgccgtctac
cccagtggtaacgctcgccccacaggcggggctggagctgtggcaatgctggttgggccc
gaggcccctctggtcctcgagagagggcttagaggaacccacatggagaacgtgtacgac
ttctacaaaccagatgtgacttcagagtacccactggtggatgggaagctctccatccag
tgctacttacgggccctggacaaatgttacgcattttaccgtcaaaagatcgagaaacag
tggaagcaagctggcatcgatcggcctttcactctcgatgatgtgcagtatatgattttt
cacacgcctttctgcaagttggtccagaaatccctggcccgcctgatgttcaatgacttc
ctgttggccagtggtgacacacagactggcgtctacaaggggttggaggccttcagggga
ctaaagctggaagacacctacaccaataaggaggtagataaagcatttctaaaagcctcc
ctgaacatgttcaataagaaaaccaagaactccctctacctctccacatacaatgggaat
atgtacacctcatccctatatggatgcctggcttcacttctggcccatcactctgcccaa
gacttggctggctccaggatcggtgccttctcttatggctctggtttggcagcaagtttc
ttttctttccgggtgtcccaggatgcttctccgggctccccgctggagaagctggtatcc
agtacatcagacctgcagaaacgtcttgcctcccggaagcgtgtgtctcctgaggagttc
acagaaataatgaaccaaagagaacaatactaccacaagatgaatttctcaccacctggt
gataagaacagccttttcccaggcacttggtacctggagcgagtggatgagctatatcgc
cgaaagtacgcccggcgccccgtctaa
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