Ovis aries (sheep): 101113251
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Entry
101113251 CDS
T03117
Name
(RefSeq) polyunsaturated fatty acid (12S)/(13S)-lipoxygenase, epidermal-type-like
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00590
Arachidonic acid metabolism
oas01100
Metabolic pathways
oas01523
Antifolate resistance
oas04726
Serotonergic synapse
oas04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
101113251
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
101113251
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101113251
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101113251
Enzymes [BR:
oas01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
101113251
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Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
101113251
NCBI-ProteinID:
XP_042111564
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Position
11:26610638..26619369
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AA seq
662 aa
AA seq
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MGKYRIRVATGDSLLAGSSNLVQLWLVGEHGEKDLGKILRPIRTREVQLEVEVSLYLGRL
LLVKLRKHKSLVGFDWFCKWIAVQGPGTQGEAFFPCYRWVQGNEIICLPEGTARTMRDDP
QNQFKKHREQELEERRKVYRWGFWKEGLILPIAGNSQWDLPRNERFLEDKDLDFSLSLAK
VLKDLALKGTLDLTNSVRRLEDFSKVFPRGKTPLAEQVRNSWKDDALFGYQFLNGANPML
LRRSTSLPSRLVLPPEMEDLKTQLEKELQTGSLFEADFSLLDGVKPNVIIFKQQYVAAPL
VMLKLQPDGRLLPMVIQLQPPRNGCPPPVLFLPSDPPMAWLLAKTWVRSSDFQLHQLQSH
LLRGHLIAEVISVATMRSLPSLHPIYKLLIPHFRYTMEINMLARSNLVSEWGIFDLVVST
GSGGHVDILQRATAGLTYRSFCPPDDLADRGLLDVKSSLYGQDALRLWGAISRYVEKMVS
LFYKSDGAVKDDPELQAWCSEITETGLQGAQDRGFPISLESRAQLCHFITMCIFTCTGQH
ASTHHGQLDWYSWIPNGPCTMRKPPPISKDVTEKDIVDALPGLHQARTQKTFIKFLGRRQ
PVMVALGQHKENYFSDPGPQAVLKQFQEELAALDKEIEVRNAGLDLPYEYLRPSMVENSV
TI
NT seq
1989 nt
NT seq
+upstream
nt +downstream
nt
atgggcaaatacaggattcgcgtcgccactggagactcgctcttggctggctccagcaac
ctggtgcagctgtggctggtgggcgagcacggggagaaggacctggggaagatactgcgg
ccgatacggaccagggaggtgcagctagaggtcgaagtctccctatatctggggcgcctc
ctgctggtgaagctgcgcaagcacaaaagcttggtgggtttcgactggttctgcaagtgg
atcgcggtccagggtcccggcacccaaggcgaggcctttttcccctgctaccgctgggtg
cagggcaacgagatcatctgcttgcccgagggcaccgcccggaccatgagggatgatccc
cagaaccagtttaagaaacatcgggagcaagagcttgaggaaagaaggaaggtgtaccga
tggggtttctggaaagagggattaatcctgcctatagcagggaattcgcaatgggatctt
cccagaaacgagagatttcttgaagataaggatttagacttcagtctctctctggcaaaa
gtgttgaaggacttggccttaaaggggacattagatctcacaaattctgtaagaagactg
gaagacttcagtaaagtattcccacgaggaaaaactcctctggctgagcaggtccgcaat
tcctggaaggatgatgccctatttgggtaccagttcctcaacggggcaaaccccatgctc
ctgagacgctccacgagtctcccgtcacggttggtgctgcctccagaaatggaagacttg
aagacacagctggagaaagaactccagactggatctctgtttgaagctgacttctccctg
ctggatggggtcaagcctaatgtcatcatttttaagcaacagtatgtagcagcccctctg
gtcatgctgaagctccagcccgatggaagactcttacctatggtcatccagctccagcca
cctcggaatggatgccccccacctgtgttgttcctgccttcagatccccccatggcctgg
ctccttgccaagacctgggtccggagctctgatttccagctgcaccagctacagtcacac
ctgctgaggggccacctgatagctgaggttatttctgtggccaccatgaggagcctgccc
agcctgcatcctatctacaagctcctgattccacactttcgctacaccatggagatcaac
atgctggcccggagtaatcttgtctctgaatggggaatttttgatctggtggtgagcact
gggagtggcggccacgtagacattctccagagagccacagctggtctgacgtatcgctcc
ttctgccctcctgatgacctggcagaccgtgggctcctggatgtgaagtcttctctctat
ggccaagatgcgctcaggctctggggagccatcagccggtatgtagagaagatggtcagt
cttttctacaagagtgatggagctgtgaaagatgatccagaactgcaggcctggtgtagc
gagatcactgagactggactgcagggggcccaggaccgggggttccccatctccttagag
tcccgagctcagctctgccacttcatcaccatgtgcatcttcacgtgcactggtcagcac
gcttccacccaccacggccagctggactggtactcctggatcccgaatggtccatgcacc
atgcggaagcctccgcccatctccaaggacgtgacagagaaggatatagtagacgcactg
cctggtctgcaccaggcccgaacacagaagaccttcataaaattccttggccgacgccag
cctgtcatggtggccttggggcagcacaaagaaaactatttctctgaccctgggcctcaa
gctgtgctgaagcaattccaggaggagttggctgccctggacaaggagattgaggtccgg
aatgcaggcctggacctgccctatgagtatcttcgacccagcatggtagagaacagtgtg
accatctga
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