Ovis aries (sheep): 101114308
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Entry
101114308 CDS
T03117
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X3
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
oas
Ovis aries (sheep)
Pathway
oas04014
Ras signaling pathway
oas04072
Phospholipase D signaling pathway
oas04148
Efferocytosis
oas04360
Axon guidance
oas04625
C-type lectin receptor signaling pathway
oas04630
JAK-STAT signaling pathway
oas04650
Natural killer cell mediated cytotoxicity
oas04660
T cell receptor signaling pathway
oas04670
Leukocyte transendothelial migration
oas04722
Neurotrophin signaling pathway
oas04920
Adipocytokine signaling pathway
oas04931
Insulin resistance
oas05168
Herpes simplex virus 1 infection
oas05205
Proteoglycans in cancer
oas05208
Chemical carcinogenesis - reactive oxygen species
oas05211
Renal cell carcinoma
oas05220
Chronic myeloid leukemia
oas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
101114308 (PTPN11)
04630 JAK-STAT signaling pathway
101114308 (PTPN11)
04072 Phospholipase D signaling pathway
101114308 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101114308 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
101114308 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
101114308 (PTPN11)
04660 T cell receptor signaling pathway
101114308 (PTPN11)
04670 Leukocyte transendothelial migration
101114308 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
101114308 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
101114308 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
101114308 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101114308 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
101114308 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101114308 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
101114308 (PTPN11)
05211 Renal cell carcinoma
101114308 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
101114308 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
101114308 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
oas01009
]
101114308 (PTPN11)
Enzymes [BR:
oas01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
101114308 (PTPN11)
Protein phosphatases and associated proteins [BR:
oas01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
101114308 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
101114308
NCBI-ProteinID:
XP_004017449
UniProt:
A0A6P3EMB8
LinkDB
All DBs
Position
17:complement(61898762..61966377)
Genome browser
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDAKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLTDQASGDQSPLPPCTPTPSCAEMREDNARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcactggcgtggaggcagaaaacctactg
ttgacaagaggagttgacggcagtttcttggcgaggcccagcaaaagcaaccctggcgac
ttcacactttccgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacctgtacggaggagagaaatttgccactttggctgaattggtccagtat
tacatggaacatcatgggcaattgaaagagaagaatggagatgtcattgagctcaaatat
cctctcaactgtgccgatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagaaaaattattaactgaaaaaggaaaacatggtagctttcttgtgcgtgagagc
cagagccaccctggagattttgttctctctgtccgaactggagatgacaaaggggagagc
aatgatgccaagtctaaagtgacccacgtcatgatccgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgactctttgacagacctcgtggagcattacaagaagaat
cctatggtagaaacattgggcacagtactacaactcaagcagcccctcaacacaactcgt
atcaatgctgctgaaatagaaagtcgggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgtaaa
cttctctatagccggaaagagggtcagaggcaagaaaataaaaacaaaaatagatataag
aacatcctgcccttcgatcacaccagggtcgtcctccacgatggtgatcccaatgagccc
gtttcggattacatcaacgcaaacattatcatgcctgaatttgaaaccaaatgcaacaac
tcaaagcccaaaaagagttacattgccacacaaggctgcctgcagaacacagtgaatgac
ttctggaggatggtgttccaagagaactcccgagtgattgtcatgacaacaaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgacgagtatgcactaaaagaatac
ggagtcatgcgtgttaggaacgtcaaggaaagtgccgctcacgactataccttaagagaa
cttaaactctcgaaggttggacaagggaatacagagagaacggtctggcaataccacttt
cggacctggccggaccacggcgtgcccagtgacccggggggcgtgctggactttctggag
gaggttcaccacaagcaggagagcattgtggatgcggggcccgtggtggttcactgcagt
gctggaattggccggacagggacgttcattgtgattgatattcttattgacatcatcaga
gagaaaggtgtcgactgtgacatcgacgttcccaaaaccattcagatggtgcggtcacag
aggtcagggatggtccagacagaagcacagtaccgattcatctatatggccgtccagcat
tatattgaaacactacagcgcaggattgaagaagagcagaaaagcaagaggaaaggacac
gaatacacaaatattaagtattccttgacggaccaggcaagtggagatcagagtcccctg
ccaccttgtaccccaacaccatcctgtgcagaaatgagagaagacaatgctagagtctat
gaaaatgtgggcctgatgcagcagcagaaaagcttcagatga
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