Ovis aries (sheep): 101115147
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Entry
101115147 CDS
T03117
Symbol
MLKL
Name
(RefSeq) mixed lineage kinase domain-like protein isoform X4
KO
K08849
mixed lineage kinase domain-like [EC:
2.7.11.1
]
Organism
oas
Ovis aries (sheep)
Pathway
oas04217
Necroptosis
oas04623
Cytosolic DNA-sensing pathway
oas04668
TNF signaling pathway
oas05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
101115147 (MLKL)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101115147 (MLKL)
09150 Organismal Systems
09151 Immune system
04623 Cytosolic DNA-sensing pathway
101115147 (MLKL)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
101115147 (MLKL)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101115147 (MLKL)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101115147 (MLKL)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: TKL group
Other
101115147 (MLKL)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MLKL_N
PK_Tyr_Ser-Thr
Pkinase
DUF7792
Motif
Other DBs
NCBI-GeneID:
101115147
NCBI-ProteinID:
XP_027833421
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Position
14:complement(1603994..1631829)
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AA seq
471 aa
AA seq
DB search
MDQLKQIISLGQLVYNQCEKMKYCQKQCRRLGNRIQGLLQPLQMLQDQGERNLPSQISTA
LSRFQAALEEAKQRIDKFSNKSDIQKFLTAGHDSIIFGGVNQRLSDVWEELSLLLQVDQW
RHTSSLSPGVSWQQEDQQDAEEDRKAIQGLSEKETVKTLLRQLESIKETVEAVQSWMRSD
SQKPKKGFPQDQIKEIKKEELPEADWILLKENESSTLYEGKYHESPVAIKVFNNSQAKDI
GIVRHTFNNEIRTMKKFDSPNILRMFGICIDETVTPPQLSIVMEYCELGTLRELLDWEKD
LTLAKRIILALGAARGLYRLHHSETPSELHRSISSTSFLVTKDYSVKLTGFELSKTLTSI
SRRTRGKAAERVSSAAYISPQRLENVYNKYDIKAEIYSFGIVLWEIATGKSPFEGCDSKK
IYQLVAESRYREPVGEDCPPQLREIVDDCRAYEPSRRPSVKEILNRLSSFY
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
atggatcagctgaagcagatcatctccttaggccagcttgtctacaaccagtgtgagaag
atgaaatactgccagaaacagtgccgacgtctagggaaccgcatccagggcctgctgcag
cctctgcaaatgctccaggaccaaggagagaggaacctgccctcccagataagcactgcg
ctgagccgtttccaggctgccctagaggaagctaagcagcggatagacaagttcagcaat
aagtccgatatccagaagtttctaacagcagggcacgacagcataatctttggtggggtg
aaccagaggctgagcgatgtctgggaggagctctctctgctgctccaggtggatcagtgg
aggcatacttcaagcctcagcccaggagtgtcttggcaacaggaagaccagcaggatgca
gaggaagacaggaaggccatccaaggactgagtgagaaagaaactgtaaaaactttattg
aggcaattggagagcataaaggaaaccgtcgaagccgtgcagagctggatgaggtcagat
tcacagaaacccaagaaggggttcccacaggatcaaatcaaggagattaagaaggaggag
cttccagaagccgattggatcctactaaaggaaaatgaatccagcacactttatgaagga
aaataccacgaatctccagtggccataaaagtattcaacaactcccaggccaaagacatt
ggaatagtgaggcatactttcaataatgaaatcagaaccatgaagaaatttgattccccc
aacatcctgcgcatgtttgggatttgcatcgatgaaacagtgacaccccctcagttatcc
atcgtcatggagtactgtgagctcgggaccctgagggagctgctggattgggaaaaggac
ctcaccctggccaagcgcatcatcctggccctgggggcagccagaggcttgtacaggctg
caccattcggaaacaccctcagaactccacaggagcatcagtagcacgagcttcctggtg
actaaagactacagtgtgaagcttacaggatttgagttgagcaaaacactgacttccatc
agccgacgaactagaggaaaagcagcagagagagtcagttctgccgcatacatctcaccc
cagaggttggaaaatgtgtataataaatacgacataaaagccgaaatatacagctttgga
attgtcctctgggagatcgccactgggaagagcccatttgaaggttgtgattccaagaag
atctaccagctggtggctgagtctcggtaccgggagccagtgggcgaagattgccctcca
cagttgcgggagatcgttgatgattgccgtgcctatgaaccctccaggaggccctctgtt
aaagaaatcttaaacagactgtcttccttttattaa
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