Ovis aries (sheep): 101116923
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Entry
101116923 CDS
T03117
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
oas
Ovis aries (sheep)
Pathway
oas04620
Toll-like receptor signaling pathway
oas04621
NOD-like receptor signaling pathway
oas04622
RIG-I-like receptor signaling pathway
oas04623
Cytosolic DNA-sensing pathway
oas04625
C-type lectin receptor signaling pathway
oas04657
IL-17 signaling pathway
oas04936
Alcoholic liver disease
oas05160
Hepatitis C
oas05161
Hepatitis B
oas05162
Measles
oas05164
Influenza A
oas05165
Human papillomavirus infection
oas05167
Kaposi sarcoma-associated herpesvirus infection
oas05168
Herpes simplex virus 1 infection
oas05169
Epstein-Barr virus infection
oas05171
Coronavirus disease - COVID-19
oas05207
Chemical carcinogenesis - receptor activation
oas05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101116923 (IKBKE)
04621 NOD-like receptor signaling pathway
101116923 (IKBKE)
04622 RIG-I-like receptor signaling pathway
101116923 (IKBKE)
04623 Cytosolic DNA-sensing pathway
101116923 (IKBKE)
04625 C-type lectin receptor signaling pathway
101116923 (IKBKE)
04657 IL-17 signaling pathway
101116923 (IKBKE)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
101116923 (IKBKE)
09172 Infectious disease: viral
05161 Hepatitis B
101116923 (IKBKE)
05160 Hepatitis C
101116923 (IKBKE)
05171 Coronavirus disease - COVID-19
101116923 (IKBKE)
05164 Influenza A
101116923 (IKBKE)
05162 Measles
101116923 (IKBKE)
05168 Herpes simplex virus 1 infection
101116923 (IKBKE)
05167 Kaposi sarcoma-associated herpesvirus infection
101116923 (IKBKE)
05169 Epstein-Barr virus infection
101116923 (IKBKE)
05165 Human papillomavirus infection
101116923 (IKBKE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101116923 (IKBKE)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101116923 (IKBKE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101116923 (IKBKE)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
101116923 (IKBKE)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: Other
IKK family [OT]
101116923 (IKBKE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
APH
CCDC24
Motif
Other DBs
NCBI-GeneID:
101116923
NCBI-ProteinID:
XP_027832032
LinkDB
All DBs
Position
12:4077942..4100585
Genome browser
AA seq
718 aa
AA seq
DB search
MQSTVNYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTASYLRPREVQVREFEVLR
KLNHQNIIKLFAVEETGAGRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVA
AGMNHLRENGIVHRDIKPGNIMRLLGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL
HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFVPFGGPRRNKEIMYRITTE
KPAGAIAGTQRRENGPLEWSYTLPITCQLSMGLQSQLVPILANILEAEQAKCWGFDQFFA
ETSDILQRGVIHVFSLPQAVLHRVYVHAHNTIAIFLEAVYEQTGVAPQHQEYLFEGHLCV
FEPGFSAQHIAHTTASSPLTLFSTASEPPKGLAFRDPALDVPKFVPKVDLQADYSTAKGI
LGAGYQALRLAQTLLGGQELMVRGLHWFVEMLQATCRRTLELSSMALLFLSSSLGPERFS
GMAEVPELQDLKRTAELRSRLRNLAEVLSRCSHNITETQKTLSDLRSELVKNRDQVHEDR
SIQQIQCCLDKMYLTYKQFKKSRMKPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQ
RYQASLVTHGKRMRLLHETRSHLRLVGCSVAACNTEAQGAQESLSKILDRLSHQLLQERT
QGAQASPPPTAPYPSSTLKDLVLHMQELCGEMKVLASDLQDNNRIIEGLSRVPLAPDI
NT seq
2157 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcactgtcaactacctgtggcacacggacgacctgctggggcagggggccacg
gccagcgtgtacaaggcccgcaacaagaaatccggggagctggttgctgtgaaggtcttc
aacacggccagctacctgcggccccgcgaggtgcaggtgagggagtttgaggtcctgcgg
aagctgaaccatcagaacattatcaagctcttcgcggtggaggagacgggggccggccgg
cagaaggtgctggtcatggagtactgctcgagcgggagcctgctgagcgtgctggagagc
cccgagaatgccttcgggctgcccgaggacgagttcctggtggtgctgcgctgcgtggcg
gccggcatgaaccacctgcgggagaacggcatcgtgcaccgcgacatcaagcccgggaac
atcatgcgcctgctgggcgaggagggccagagcatctacaagctgaccgacttcggggcc
gcccgcgagctggatgacgacgagaagttcgtctcagtctacggcaccgaggagtatctg
caccctgacatgtacgagcgggcggtgcttcgcaagccccagcagaaagcttttggggtg
accgtggatctttggagcatcggggtgaccctgtaccacgcagccaccggcagcttgccc
ttcgtcccatttggcgggccccggcgcaacaaggagatcatgtaccgcatcaccacggag
aagccagccggggccattgcgggcacccagaggcgggagaatgggcccctggagtggagc
tacaccctgcccatcacctgccagctgtccatgggtctgcagagccagctggtgcccatc
ctggccaacatcctggaggcagagcaggccaagtgctggggcttcgaccagttcttcgca
gagaccagcgacatcctgcagcgaggcgtgatccacgtgttctccctgccccaggcagtc
ctgcaccgcgtctatgtccacgcgcacaacacgatagccatcttcctggaggccgtgtac
gagcagacgggtgtggctccccagcaccaggagtacctctttgagggtcacctgtgtgtc
tttgagcccggcttctctgctcagcacatcgcccacaccacagcgagcagccccctgacc
ctgttcagcacagccagcgagccccccaaggggctggccttcagggaccccgctctggac
gttcccaagtttgtccccaaagtggatctgcaggcagattacagcacagctaagggcatc
ttgggtgccggctaccaggccctgcggctggcgcagactctgctgggagggcaggagctg
atggttcggggtctgcactggttcgtggagatgctccaggccacgtgcaggcggacgctg
gagctctcgagcatggctctcctcttcctcagcagcagcctcggccctgagaggtttagc
ggcatggccgaggtgcctgagctccaggacctgaagaggaccgcagagctgaggtccagg
ctgcgtaatttggctgaggtcctctccagatgctcccacaatatcacggaaactcagaag
accctgagcgacctgcgctctgagctggtgaagaaccgggatcaggtacatgaggacaga
agcatccagcagattcagtgctgtttggacaaaatgtacctcacctacaaacagttcaag
aaatccagaatgaagccagggctgggctacaacgaggagcagattcacaagctggacaag
gtgaattttagtcatttagccaaaaggctcctgcaggtgttccaggaggagtgtgtgcag
aggtaccaggcatccctggtcacacacggcaagcgaatgaggttgctgcatgagaccagg
agccacctgcgcctggtgggctgctccgtggctgcctgcaacacggaagcccagggagcc
caggagagcctcagcaagatccttgaccgactatctcaccagctcctgcaagagagaaca
cagggggctcaggcctccccacccccgacagctccttatcccagctctacgctgaaggac
ctagttctccacatgcaagagctctgtggggagatgaaggtgctggcgtctgacctccag
gacaacaaccgcatcatcgaagggctaagcagggtcccactggctcctgacatctga
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