Ovis aries (sheep): 101118041
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Entry
101118041 CDS
T03117
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
oas
Ovis aries (sheep)
Pathway
oas04120
Ubiquitin mediated proteolysis
oas04144
Endocytosis
oas04330
Notch signaling pathway
oas04668
TNF signaling pathway
oas04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101118041 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101118041 (ITCH)
04668 TNF signaling pathway
101118041 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101118041 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101118041 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
oas04131
]
101118041 (ITCH)
04121 Ubiquitin system [BR:
oas04121
]
101118041 (ITCH)
Enzymes [BR:
oas01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
101118041 (ITCH)
Membrane trafficking [BR:
oas04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
101118041 (ITCH)
Ubiquitin system [BR:
oas04121
]
Ubiquitin ligases (E3)
HECT type E3
101118041 (ITCH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
101118041
NCBI-ProteinID:
XP_027832904
LinkDB
All DBs
Position
13:63782096..63882094
Genome browser
AA seq
862 aa
AA seq
DB search
MSGSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAGLDIYETLKSNNMKLEEVVVTL
QLVGDKEPAETIGDLSVCLDGLQLESEVVPNGETACSESASQNDDGSRPKDETRANASGS
DDPEDAGPGENRRINGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSTTSESD
GSSTGSLPPTNTNSSTSEGATSGLIIPLTISGGAGPRPLNPVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRNQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctggcagtggatcacagcttggttcaatgggtagtttgaccatgaaatcacaactt
cagatcactgtcatttcagcaaagcttaaagagaataaaaagaattggtttgggccaagt
ccttatgtggaagtcacagtagacggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcagcctctcacagttattgtcacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctggattg
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagaaccagcagagacaataggagatttgtcagtctgtcttgac
gggctgcaactagagtctgaagttgttcccaatggtgaaactgcatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagagcgaatgcaagtggatca
gatgaccctgaggatgcagggcctggtgaaaataggaggatcaatgggaacaattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggctcaccatctaccacttctgaaagtgat
ggctctagtacaggctctctgccaccaacaaatacaaattcaagtacatctgaaggagca
acatctggattaataattcctcttactatatctggaggtgcaggccctagaccattaaat
cctgtacctcaagctcccctcccacctggttgggagcagagagtggaccagcatgggcga
gtttattatgtagatcatattgaaaaaagaacgacgtgggatagaccagaacctctacct
cctggctgggagcggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacattggaatccgtccgaaactatgaacaatggcag
ctccagcgtagtcaacttcagggagctatgcagcaatttaaccagaggttcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgccg
cctggatgggagaagagaacggacagcaatggtagagtatattttgtcaaccacaacact
cgtattacacaatgggaagaccccagaaatcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacggtagatggaattccgtattttgtggaccacaataga
agaacaaccacctatatagatccccgcaccggaaaatctgccttagacaatggaccccag
atagcctatgtacgggacttcaaggcaaaggttcagtatttccgtttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtcctcaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcaggtttattgcaatggctctgttccatgggaaattcatagacacaggtttttctttg
ccattctataagcgtatcttgaataaaccagttggactgaaggatttagaatcgattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggagtgtggtttg
gaaatgtatttctccgttgataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggagattgtctcgtggtgttgaagaacagacgcaagctttctttgagggcttt
aatgaaattcttccccagcaatatttacagtactttgatgcaaaggaattagaggttctt
ttatgtgggatgcaagagattgatttgaatgattggcaaagacatgccatctaccgtcat
tatactaggacaagtaaacaaatcatgtggttttggcagtttgttaaagaaatcgataat
gagaagagaatgcggcttttgcagtttgttactgggacctgccgactaccagttggagga
tttgctgacctcatggggagcaatgggccacagaagttctgcattgaaaaagtcgggaaa
gaaaattggttgcctagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgctattgaagaaacagaaggctttgga
caagagtga
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