Ovis aries (sheep): 101121018
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Entry
101121018 CDS
T03117
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X2
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
oas
Ovis aries (sheep)
Pathway
oas01524
Platinum drug resistance
oas04010
MAPK signaling pathway
oas04071
Sphingolipid signaling pathway
oas04141
Protein processing in endoplasmic reticulum
oas04210
Apoptosis
oas04530
Tight junction
oas04668
TNF signaling pathway
oas04714
Thermogenesis
oas04722
Neurotrophin signaling pathway
oas04932
Non-alcoholic fatty liver disease
oas04936
Alcoholic liver disease
oas05010
Alzheimer disease
oas05012
Parkinson disease
oas05014
Amyotrophic lateral sclerosis
oas05016
Huntington disease
oas05017
Spinocerebellar ataxia
oas05022
Pathways of neurodegeneration - multiple diseases
oas05208
Chemical carcinogenesis - reactive oxygen species
oas05417
Lipid and atherosclerosis
oas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101121018 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101121018 (MAP3K5)
04668 TNF signaling pathway
101121018 (MAP3K5)
04071 Sphingolipid signaling pathway
101121018 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
101121018 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
101121018 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101121018 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
101121018 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101121018 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
101121018 (MAP3K5)
05012 Parkinson disease
101121018 (MAP3K5)
05014 Amyotrophic lateral sclerosis
101121018 (MAP3K5)
05016 Huntington disease
101121018 (MAP3K5)
05017 Spinocerebellar ataxia
101121018 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
101121018 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101121018 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
101121018 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101121018 (MAP3K5)
04932 Non-alcoholic fatty liver disease
101121018 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101121018 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oas01001
]
101121018 (MAP3K5)
Enzymes [BR:
oas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
101121018 (MAP3K5)
Protein kinases [BR:
oas01001
]
Serine/threonine kinases: STE group
STE11 family
101121018 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
101121018
NCBI-ProteinID:
XP_004011568
LinkDB
All DBs
Position
8:complement(61835832..62064323)
Genome browser
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSYRRGGAATAAEGEETQLPPPPPGSFWNVESAAAPGAGCP
SATAGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVVAESEALQCLREACETVGAALE
TLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTN
SDSLQSLKEIICQKNTMCTGNYTFIPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQNEEQVASDMYCLVGRIYKDMFLDSNFMDTESRDHGASWFKKAFESEPT
LQSGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTSEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGKNTEEGDCEG
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRDCANDLLMDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHIT
TLVTSLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEGDHDERPSNQTVR
RPHAVLEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDQEIKHLKLKSQPIDIPGLPACHSSSPGTNTEDSELTDWLRENGADEDTIS
RFLAEDYSLMDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQA
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttctccgtgccgcccttcgccgagggcggc
agctaccggaggggaggagcggcgacggcggccgagggcgaggagacccagctgccaccg
ccgccaccgggcagcttctggaacgtggaaagtgccgccgctcccggcgccgggtgtccc
agtgccaccgctgggagcagcgccacccggtgccggggcaactctgggggcggaggcggc
cgacggaccacggtggcctatgtcatcaacgaggcgagccaggggcagctggtggtggcc
gagagcgaggccctgcagtgcctgcgggaggcgtgcgagacggtgggcgccgccctggag
accctgcattttgggaaactggactttggagaaactgcggtgctggaccgattttacaat
gcagatatcgccgtggtggagatgagcgatgccttccgacaaccatccttattttaccac
ctgggagtgcgagaaagtttcagcatggccaacaacatcatcctctactgtgatactaat
tcagactctctgcagtcactgaaggagatcatttgccagaagaatactatgtgcactggg
aactacacatttattccttacatgataacgccgcataacaaggtctactgctgtgacagc
agcttcatgaagggcttgactgagctcatgcagccgaactttgagctgcttctgggaccc
atctgcttacctcttgtggatcgtttcattcagctcttgaaggtggcacaagcaagttcc
agccagtatttccgggagtctatactcaatgatatcaggaaagctcgtaacttatatact
ggcaaagaactggcagctgaattggcaagaattcgacagcgagtggataatattgaagtc
ttgacagcagatattgtcataaatctgttactttcatatagagatatccaggactatgat
tctattgtgaagctggtagagactttagaaaagcttccaacgtttgatttggcctcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaacctccctggagatagg
gcaaaagctcttgacattatgattcccctggtgcaaaatgaagagcaggttgcttcagat
atgtattgccttgttggtcgaatctacaaagatatgtttttggactctaatttcatggac
actgaaagtagagaccatggagcctcttggttcaaaaaggcatttgaatcagagccaaca
ctacagtcaggaattaattatgcggtcctcctcctggcatctgggcaccagtttgaatct
tcctttgagctccgaaaagttggggtgaagctaagtagtcttcttggtaaaaagggaaac
ttggaaaaacttcagagctactgggaagttggatttttcctgggggccagtgtcctggcc
aatgaccacttgagagtcattcaagcatctgaaaagctttttaaactgaagacacctgca
tggtacctcaagtctatcgtagagacaattttgatatataagcattttgtgaaactgact
tcggaacagcctgtggccaaacaggaacttgtggacttctggatggatttcctggtcgag
gccacaaagacagatgtcactgtagttaggtttccagtattaatattagaaccaaccaaa
atctatcaaccttcgtatttgtctatcaacaatgaagttgaggaaaagacaatatctatt
tggcacgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggtgtgagtatttctaaatttgaagaacgatgctgttttctgtatgtgcttcac
aattctgacgatttccaaatctatttctgtacagaacttcactgtaaaaagttttttgaa
atggtgaacaccattactgaagagaaggggaaaaacacagaggaaggagattgtgaaggt
gactccctggagtatgactatgaatatgatgaaaatggtgacagagtcgttttaggaaaa
ggcacttatgggatagtttatgcaggtcgagatctgagcaaccaagtcagaatcgccatt
aaggaaatcccagaaagagacagcagatactcccagcccctgcatgaagaaatagccttg
cataagcatctgaagcacaaaaatattgtccagtatctgggctctttcagtgaaaatggt
ttcattaaaatcttcatggagcaggtcccaggaggaagtctttctgctctccttcgttcc
aaatggggcccactgaaagacaatgagcaaacaatcggcttttatacaaagcaaatcctg
gaaggattaaaatacctccatgacaatcagatagttcaccgggatataaagggtgacaat
gtgttgattaatacctatagtggtgttctcaagatttctgatttcggaacatcaaagagg
cttgctggcataaatccatgtactgaaacttttactggtaccctccagtatatggcacca
gaaataatagataaaggaccaagaggctatggaaaggcagcagacatttggtctctgggc
tgcacaatcattgaaatggccactggaaaaccacccttttatgaactgggggaaccacaa
gcagctatgttcaaggtggggatgtttaaagtccacccagagatcccagagtccatgtca
gcagaggccaaggcgttcatattgaagtgtttcgaaccagaccctgacaaaagagactgt
gctaacgacttgcttatggatgagttcttaaaagtttcaagcaaaaagaaaaagacacag
cctaagctttcagctctttcagctggatcgaatgagtacctcaggagtatctccttgccc
gtgccagtcctggtggaggacacaagcagcagcagcgagtacggctcagtttcccccgac
acagagttaaaggtggaccccttctctttcaaaacaagagccaagtcctgtggagaaaag
gatgtcaaaggcatacggacgttgtttctgggcatccctgatgaaaattttgaagaccac
agtgctccaccttctccagaagaaaaagattctggattctttatgctgaggaaggacagt
gagagacgggccacgcttcacaggattctgacggaagaccaggacaaagttgtgagaaac
ttaatggaatccttggctcagggggccgaagagcctaaactaaaatgggaacacatcaca
actctcgtcacaagcctcagagaatttgtgaggtccacagaccggaagatcatagccacc
accctgtctaagctgaagctggagctggactttgacagccatgggatcagtcaggtccag
gtggtgctctttggttttcaagatgctgtcaataaagttcttcggaatcataacatcaag
ccacactggatgtttgctttagacagtatcatccgaaaggcggtacagacagctattacc
attctggttccagaactgaggccacatttcagccttgcatctgagagtgatactgccgat
caagaagacttggatgcagaaggtgaccatgatgaacggccttcaaatcaaactgtccga
agacctcatgcagtccttgaagacgcggtggccacctcaggggtgagcacgctcagttct
actgtatcccatgactcccagagtgctcaccgatcactgaatgtacaacttggaaggatg
aaaatagaaacaaatagattactggaagaattggttcagaaagagaaagaattacaagca
ctccttcatcaagctattgaagagaaagaccaagaaattaaacacctgaagcttaagtcc
caaccaatagatattcctgggttgcctgcgtgtcactccagttctcctggcacaaacact
gaagattctgaacttactgactggctgagagaaaacggagccgatgaagacactataagt
cggtttttggctgaggattattcattaatggatgttctctactatgttacacgtgatgat
ttaaaatgcctgagactaaggggcgggatgctgtgcacactgtggaaagccatcactgac
ttccgagacaaacaggcttga
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