KEGG   Ovis aries (sheep): 101121421
Entry
101121421         CDS       T03117                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
oas  Ovis aries (sheep)
Pathway
oas00670  One carbon pool by folate
oas00790  Folate biosynthesis
oas01100  Metabolic pathways
oas01240  Biosynthesis of cofactors
oas01523  Antifolate resistance
oas04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:oas00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    101121421 (DHFR)
   00670 One carbon pool by folate
    101121421 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    101121421 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101121421 (DHFR)
Enzymes [BR:oas01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     101121421 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 101121421
NCBI-ProteinID: XP_004009103
UniProt: W5PZI9
LinkDB
Position
5:complement(78304510..78323826)
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGNLPWPPLRNEFKYFQRMTTVSSEEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRELKEPPKGAHFLAKSLDDALELIEDPELTNKVDMVWIVGGSS
VYKEAMNKPGHLRLFVTRIMQEFESDVFFPEIDFEKYKLLPEYPGVPLDVQEEKGIKYKF
EVYEKNN
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaactgcatcgtcgctgtgtcccagaacatgggcatcggcaagaac
gggaacctgccctggccaccactcaggaatgaattcaagtatttccaaagaatgactaca
gtctcttcagaagaaggtaaacagaatttggtgattatgggtaggaagacctggttctcc
attccagagaagaatcgacctttaaaggacagaattaatatagttctcagtagagaactc
aaggaacctccaaagggagctcattttcttgccaaaagtctggatgatgccttagaactt
attgaagatccagaattaacaaataaagtagacatggtttggatagtgggaggcagttct
gtatataaggaagccatgaacaagccaggccatcttagactatttgtgacaaggatcatg
caagaatttgaaagtgatgtgtttttcccagaaattgattttgaaaaatataaacttctt
ccagaatatccaggtgttcctttggatgtccaggaggaaaaaggcattaagtacaaattt
gaagtatatgaaaagaacaattaa

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