Ovis aries (sheep): 101122979
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Entry
101122979 CDS
T03117
Symbol
HMGCS1
Name
(RefSeq) hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X2
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
oas
Ovis aries (sheep)
Pathway
oas00280
Valine, leucine and isoleucine degradation
oas00650
Butanoate metabolism
oas00900
Terpenoid backbone biosynthesis
oas01100
Metabolic pathways
oas03320
PPAR signaling pathway
Module
oas_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
oas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
101122979 (HMGCS1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
101122979 (HMGCS1)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
101122979 (HMGCS1)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
101122979 (HMGCS1)
Enzymes [BR:
oas01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
101122979 (HMGCS1)
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GFIT
Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
Cullin
Motif
Other DBs
NCBI-GeneID:
101122979
NCBI-ProteinID:
XP_004017060
UniProt:
A0A6P3T5V7
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Position
16:31544055..31566693
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AA seq
520 aa
AA seq
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MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCT
DREDINSLCMTVVQNLMERNSLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDI
EGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVAML
IGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDHCYSVYRKKI
HARWQKEGNDRDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEA
FGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLAQY
SPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKIVASICDLKSRLDSRTCVAP
DIFAENMKLREDTHHLANYIPQSSIDSLFEGTWYLVRVDEKHRRTYARRPSLNDDTLDEG
VGLVPSSTTAEHIPSPAKKVPRLPATAAEPEAAVISNGEH
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgcctgggtcacttcctttgaatgcagaagcctgctggcccaaagatgtaggaattgtt
gcccttgagatctattttccttctcaatatgttgatcaggcagagttggaaaaatacgat
ggtgtagacgctggaaagtatactattggcttgggccaggccaagatgggcttctgcaca
gatagagaagatatcaactctctgtgcatgactgtggtccagaatcttatggagagaaat
agcctttcttatgactgcattgggcggctagaagttggaacggagacaatcatcgacaaa
tcaaagtcagtgaagacgaatttgatgcagctctttgaggagtctgggaatacggatata
gaaggaatagacacaactaatgcgtgctatggaggcacagccgctgtcttcaatgctgtt
aactggatcgagtccagctcttgggatggacggtatgccctggtagttgcaggggatatt
gccgtatatgccacaggaaatgccagacctacaggtggagttggagccgttgctatgcta
attgggcctaatgcacctttaatttttgaacgaggacttcgtgggactcatatgcaacat
gcctatgacttttacaagcctgatatgctttctgaatatccgatagtagatggaaaactg
tccatacagtgctacctcagtgcattagaccactgctattctgtctaccgcaagaagatc
cacgcccggtggcagaaagagggaaatgatagagatttcaccttgaatgattttggtttc
atgatattccactcaccctattgtaaactggttcagaaatctctagctcggatgttgctg
aatgacttccttaatgaccagaacagagataaaaatagtatctacagtggcctagaagcc
tttggggatgttaaattagaagatacctactttgacagagatgtggaaaaggcatttatg
aaagctagttcagaactcttcaatcagaaaacaaaggcatctttgcttgtgtcaaatcaa
aatggaaatatgtacacatcttcagtgtatggctccctggcttctgttctcgcacagtac
tcacctcagcagctggcaggaaagaggatcggcgtgttttcttacggttctggtttggct
gccactctgtactccctcaaagttacacaagatgccacaccagggtccgctcttgataaa
atagtagcaagcatatgtgatcttaagtcaaggcttgactcgagaacttgtgtggcacca
gatatctttgctgaaaacatgaagctccgagaggatactcatcacttggccaactacatt
ccccagagttccatagattccctcttcgaaggaacatggtacctagttcgagtagatgaa
aaacacagaagaacctacgctcggcgcccctctctaaacgacgacactttggatgaggga
gtaggccttgtgccctcgagcactacagccgagcatattccaagtcctgctaagaaagtg
ccaaggctccctgcaacagcagcagaacctgaagcagctgtcatcagtaacggggagcat
taa
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