KEGG   Ovis aries (sheep): 101123550
Entry
101123550         CDS       T03117                                 
Symbol
CACNA2D1
Name
(RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1
  KO
K04858  voltage-dependent calcium channel alpha-2/delta-1
Organism
oas  Ovis aries (sheep)
Pathway
oas04010  MAPK signaling pathway
oas04260  Cardiac muscle contraction
oas04261  Adrenergic signaling in cardiomyocytes
oas04921  Oxytocin signaling pathway
oas05410  Hypertrophic cardiomyopathy
oas05412  Arrhythmogenic right ventricular cardiomyopathy
oas05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101123550 (CACNA2D1)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    101123550 (CACNA2D1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    101123550 (CACNA2D1)
   04261 Adrenergic signaling in cardiomyocytes
    101123550 (CACNA2D1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101123550 (CACNA2D1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    101123550 (CACNA2D1)
   05414 Dilated cardiomyopathy
    101123550 (CACNA2D1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:oas04040]
    101123550 (CACNA2D1)
Ion channels [BR:oas04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   101123550 (CACNA2D1)
SSDB
Motif
Pfam: VGCC_alpha2 VWA_N VWA VWA_3 VWA_2 MCP-like_PDC_1 dCache_1 IFN-gamma
Other DBs
NCBI-GeneID: 101123550
NCBI-ProteinID: XP_027824343
LinkDB
Position
4:39570745..40111177
AA seq 1110 aa
MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDI
YEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASN
EVVYYNAKDDLDPEKNDSEPGSQRIKPVFIDDANFGRQISYQHAAVHIPTDIYEGSTIVL
NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
FTDGGEERAQEIFTKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
INTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQNENKTNLK
NQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIGIGIPTIN
LRKRRPNVQNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFKTLVKSQDERYI
DKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKIEETITQARSKKGRMKDSETLKPDNF
EESGYTFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNTDLINRVLLDAGFTN
ELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNY
VFTAPYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDP
CAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYA
YNKSYDYQSVCEPGAAPKQGAGHRSAYVPSIADILHIGWWATAAAWSILQQFLLSLTFPR
LLEAVEMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHVEKLMNTNL
IFIMVESKGTCPCDTRLLIQAEQTSDGPDPCDMVKQPRYRKGPDVCFDNNALEDYTDCGG
VSGLNPSLWSIIGIQCVLLWLLSGSRHQQL
NT seq 3333 nt   +upstreamnt  +downstreamnt
atggctgctggctgcctgctggccttgactctgacacttttccaatctttgttgatcggc
ccctcgtcggaggagccgttcccttcggccgtcactatcaagtcatgggtggataagatg
caagaagacctcgtcaccctggcaaaaacagcaagtggagtcaatcagcttgtcgatatt
tatgagaaataccaagatttgtatactgtggagccaaataatgcacgccagctggtggaa
attgcagccagggatattgaaaaacttctgagcaacagatccaaagccctggtgcgtcta
gctttggaagcagaaaaagttcaagcagcccaccagtggagagaggatttcgcaagcaat
gaagttgtctactacaatgcaaaggatgatcttgatccagaaaagaatgatagcgaacca
ggcagccagaggataaaacctgtttttatcgatgacgctaattttgggcgacaaatatcc
tatcagcacgcagccgttcatattcccactgacatctatgagggctcaacaattgtatta
aatgaactcaactggacaagtgccttagatgaagttttcaagaaaaatcgagaagaagat
ccttcattattgtggcaggtgtttggcagtgccacaggcctggcccgatattatccagct
tctccatgggttgataacagtagaactccaaacaagattgacctttatgatgtacgcagg
agaccatggtacatccaaggagctgcatctcctaaagacatgcttatactggttgatgtg
agcgggagtgttagtggattgacacttaaactgatccgaacatctgtctccgaaatgttg
gaaaccctctcagatgatgattttgtgaatgtagcttcatttaacagcaatgcccaggat
gtaagctgttttcagcacctcgtccaagcaaatgtgagaaataagaaagtgttgaaagat
gcggtgaataatatcacagcaaaaggaatcacagattataagaagggatttagttttgct
tttgaacagctgcttaattataatgtgtctagagccaactgcaataagattatcatgttg
ttcacggatggaggagaagagagagctcaggagatatttaccaaatacaacaaagacaaa
aaggtccgtgtattcacattttcagttggtcaacataattatgacagaggacctattcaa
tggatggcctgtgaaaataaaggttattattatgaaattccttccattggagcaataaga
atcaatactcaggaatatttggatgttctgggaagaccaatggttttagctggagacaaa
gctaagcaagttcagtggacaaacgtatacctggatgcactggaactgggacttgtcatt
actggaactcttccggtcttcaacataaccggccaaaatgaaaataagacaaacttaaag
aatcagctgattcttggtgtaatgggagttgatgtgtctttggaagatattaaaagacta
acaccacgttttacattgtgccccaacggctattattttgcaattgatcctaatggttat
gttttattacatccaaatcttcagccaaagcctattggcataggtataccaacaattaat
ttaagaaaaaggagacccaatgttcagaaccccaaatctcaggagcctgtaactttggat
ttccttgatgcagaattagagaacgatattaaagtggagattcgaaataaaatgatagat
ggagaaagcggagaaaaaacattcaagactctggttaaatctcaagatgagagatacatt
gacaaaggaaacaggacatatacatggactcctgtcaatggcacagattacagtttggcc
ttggtattaccaacctacagtttttactatataaaagccaaaatagaagagacaataact
caggccagatccaaaaagggcagaatgaaggattcagaaactctgaaaccggataatttt
gaagaatctggctatacattcatagcaccaagagattactgcaatgaccttaaaatatca
gataacaacaccgaatttcttttaaattttaatgagtttattgatagaaaaactccaaac
aacccatcatgcaacacagacttgattaatagagtcttgctggatgcaggctttacaaat
gaacttgtccaaaattactggagtaagcagaaaaacatcaagggagtgaaagcacgattt
gttgtgactgatggtgggattaccagagtttatccgaaagaggctggagaaaattggcaa
gaaaacccagaaacatatgaggacagcttctataaaagaagtctagataacgataactat
gttttcactgctccctactttaacaaaagtggacctggtgcttatgaatcaggcattatg
gtaagcaaagctgtagaaatttacatccaaggaaaacttcttaaacctgcagttgttgga
attaaaattgatgtaaattcctggatagagaatttcaccaaaacatcaatcagggatccg
tgtgcgggtccagtttgtgactgtaaaagaaacagtgatgtaatggattgtgttattcta
gatgatggtgggttccttttgatggcaaatcatgatgattatactaaccagattggaagg
ttttttggagagattgatccaagtttgatgagacacctggttaatatatcagtttatgct
tataacaagtcttacgattatcagtcggtgtgtgagccaggagctgcaccaaaacaagga
gcagggcatcgctcagcatacgtgccatcaatagccgacatattacacattggctggtgg
gccactgctgctgcctggtctattctacagcagtttctcttgagtttgacctttccacga
cttcttgaggcagttgagatggaagatgatgactttacggcctctctgtcaaagcagagt
tgcattactgaacaaactcaatattttttcgataacgatagtaaatcatttagtggtgta
ttagattgtggaaactgttccagaatcttccatgtagaaaaacttatgaacaccaattta
atattcataatggttgagagcaaaggaacttgtccctgtgacacacggttgctcatacaa
gcagagcagacttctgatggtccagatccttgtgatatggtgaagcaacccagataccga
aaagggcctgatgtctgctttgataacaatgctttggaggattataccgactgtggtggt
gtctctggattaaacccctccctgtggtccatcatcggcatccagtgtgtactactttgg
cttttatctggcagcagacaccagcagttatga

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