Ovis aries (sheep): 443406 Help Entry 443406            CDS       T03117                                  Symbol IL6 Name (RefSeq) interleukin-6 precursor   KO K05405   interleukin 6 Organism oas  Ovis aries (sheep) Pathway oas01521   EGFR tyrosine kinase inhibitor resistance oas01523   Antifolate resistance oas04060   Cytokine-cytokine receptor interaction oas04061   Viral protein interaction with cytokine and cytokine receptor oas04066   HIF-1 signaling pathway oas04068   FoxO signaling pathway oas04151   PI3K-Akt signaling pathway oas04218   Cellular senescence oas04620   Toll-like receptor signaling pathway oas04621   NOD-like receptor signaling pathway oas04623   Cytosolic DNA-sensing pathway oas04625   C-type lectin receptor signaling pathway oas04630   JAK-STAT signaling pathway oas04640   Hematopoietic cell lineage oas04657   IL-17 signaling pathway oas04659   Th17 cell differentiation oas04668   TNF signaling pathway oas04672   Intestinal immune network for IgA production oas04931   Insulin resistance oas04932   Non-alcoholic fatty liver disease oas04933   AGE-RAGE signaling pathway in diabetic complications oas04936   Alcoholic liver disease oas05010   Alzheimer disease oas05020   Prion disease oas05022   Pathways of neurodegeneration - multiple diseases oas05132   Salmonella infection oas05133   Pertussis oas05134   Legionellosis oas05135   Yersinia infection oas05142   Chagas disease oas05143   African trypanosomiasis oas05144   Malaria oas05146   Amoebiasis oas05152   Tuberculosis oas05161   Hepatitis B oas05162   Measles oas05163   Human cytomegalovirus infection oas05164   Influenza A oas05166   Human T-cell leukemia virus 1 infection oas05167   Kaposi sarcoma-associated herpesvirus infection oas05168   Herpes simplex virus 1 infection oas05169   Epstein-Barr virus infection oas05171   Coronavirus disease - COVID-19 oas05200   Pathways in cancer oas05202   Transcriptional misregulation in cancer oas05321   Inflammatory bowel disease oas05323   Rheumatoid arthritis oas05332   Graft-versus-host disease oas05410   Hypertrophic cardiomyopathy oas05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:oas00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     443406 (IL6)    04668 TNF signaling pathway     443406 (IL6)    04066 HIF-1 signaling pathway     443406 (IL6)    04068 FoxO signaling pathway     443406 (IL6)    04151 PI3K-Akt signaling pathway     443406 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     443406 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     443406 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     443406 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     443406 (IL6)    04620 Toll-like receptor signaling pathway     443406 (IL6)    04621 NOD-like receptor signaling pathway     443406 (IL6)    04623 Cytosolic DNA-sensing pathway     443406 (IL6)    04625 C-type lectin receptor signaling pathway     443406 (IL6)    04659 Th17 cell differentiation     443406 (IL6)    04657 IL-17 signaling pathway     443406 (IL6)    04672 Intestinal immune network for IgA production     443406 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     443406 (IL6)    05202 Transcriptional misregulation in cancer     443406 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     443406 (IL6)    05161 Hepatitis B     443406 (IL6)    05171 Coronavirus disease - COVID-19     443406 (IL6)    05164 Influenza A     443406 (IL6)    05162 Measles     443406 (IL6)    05168 Herpes simplex virus 1 infection     443406 (IL6)    05163 Human cytomegalovirus infection     443406 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     443406 (IL6)    05169 Epstein-Barr virus infection     443406 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     443406 (IL6)    05135 Yersinia infection     443406 (IL6)    05133 Pertussis     443406 (IL6)    05134 Legionellosis     443406 (IL6)    05152 Tuberculosis     443406 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     443406 (IL6)    05144 Malaria     443406 (IL6)    05142 Chagas disease     443406 (IL6)    05143 African trypanosomiasis     443406 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     443406 (IL6)    05321 Inflammatory bowel disease     443406 (IL6)    05332 Graft-versus-host disease     443406 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     443406 (IL6)    05020 Prion disease     443406 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     443406 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     443406 (IL6)    05410 Hypertrophic cardiomyopathy     443406 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     443406 (IL6)    04932 Non-alcoholic fatty liver disease     443406 (IL6)    04931 Insulin resistance     443406 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     443406 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     443406 (IL6)    01523 Antifolate resistance     443406 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:oas04052]     443406 (IL6) Cytokines and neuropeptides [BR:oas04052]  Cytokines   Interleukins    443406 (IL6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IL6 IL23 GCSF MIP-T3_C Sec16 Beta-prop_NUP159_NUP214 Motif Other DBs NCBI-GeneID:  443406 NCBI-ProteinID:  NP_001009392 UniProt:  P29455 B7TXY8 LinkDB All DBs Position 4:32358906..32363261 Genome browser AA seq 208 aa AA seqDB search MNSLFTSAFSPLAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPSRLLLTTPEKTEALIKHI VDKISAIRKEICEKNDECENSKETLAENKLKLPKMEEKDGCFQSGFNQAICLIKTTAGLL EYQIYLDFLQNEFEGNQETVMELQSSIRTLIQILKEKIAGLITTPATHTDMLEKMQSSNE WVKNAKVIIILRSLENFLQFSLRAIRMK NT seq 627 nt NT seq  +upstreamnt  +downstreamnt atgaactccctcttcacaagcgccttcagtccactcgctgtctccctggggctgctcctg gtgatgacttctgctttccctaccccgggtcccctgggagaagatttcaaaaatgacacc accccaagcagactacttctgaccactccagaaaaaaccgaagctctcattaagcacatc gtcgacaaaatctctgcaataagaaaggagatatgtgagaagaatgacgagtgtgaaaac agcaaggagacactggcagaaaataagctgaaacttccaaaaatggaggaaaaagatgga tgcttccaatctgggttcaatcaggcgatttgcttgatcaaaaccactgctggtcttctg gagtatcagatatacctggacttcctccagaacgagtttgagggaaatcaggaaactgtc atggagttgcagagcagtatcagaacactgatccagatcctgaaggaaaagatcgcaggt ctaataaccactccagccacacacactgacatgctggagaagatgcagtcctcaaacgag tgggtaaagaacgcaaaggttatcatcatcctgagaagccttgagaatttcctgcagttc agcctgagagctattcggatgaagtag

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