Ovis aries (sheep): 443540 Help Entry 443540            CDS       T03117                                  Symbol TNF Name (RefSeq) tumor necrosis factor   KO K03156   tumor necrosis factor superfamily, member 2 Organism oas  Ovis aries (sheep) Pathway oas01523   Antifolate resistance oas04010   MAPK signaling pathway oas04060   Cytokine-cytokine receptor interaction oas04061   Viral protein interaction with cytokine and cytokine receptor oas04064   NF-kappa B signaling pathway oas04071   Sphingolipid signaling pathway oas04150   mTOR signaling pathway oas04210   Apoptosis oas04217   Necroptosis oas04350   TGF-beta signaling pathway oas04380   Osteoclast differentiation oas04612   Antigen processing and presentation oas04620   Toll-like receptor signaling pathway oas04621   NOD-like receptor signaling pathway oas04622   RIG-I-like receptor signaling pathway oas04625   C-type lectin receptor signaling pathway oas04640   Hematopoietic cell lineage oas04650   Natural killer cell mediated cytotoxicity oas04657   IL-17 signaling pathway oas04660   T cell receptor signaling pathway oas04664   Fc epsilon RI signaling pathway oas04668   TNF signaling pathway oas04920   Adipocytokine signaling pathway oas04930   Type II diabetes mellitus oas04931   Insulin resistance oas04932   Non-alcoholic fatty liver disease oas04933   AGE-RAGE signaling pathway in diabetic complications oas04936   Alcoholic liver disease oas04940   Type I diabetes mellitus oas05010   Alzheimer disease oas05014   Amyotrophic lateral sclerosis oas05020   Prion disease oas05022   Pathways of neurodegeneration - multiple diseases oas05132   Salmonella infection oas05133   Pertussis oas05134   Legionellosis oas05135   Yersinia infection oas05140   Leishmaniasis oas05142   Chagas disease oas05143   African trypanosomiasis oas05144   Malaria oas05145   Toxoplasmosis oas05146   Amoebiasis oas05152   Tuberculosis oas05160   Hepatitis C oas05161   Hepatitis B oas05163   Human cytomegalovirus infection oas05164   Influenza A oas05165   Human papillomavirus infection oas05166   Human T-cell leukemia virus 1 infection oas05168   Herpes simplex virus 1 infection oas05169   Epstein-Barr virus infection oas05170   Human immunodeficiency virus 1 infection oas05171   Coronavirus disease - COVID-19 oas05205   Proteoglycans in cancer oas05310   Asthma oas05321   Inflammatory bowel disease oas05322   Systemic lupus erythematosus oas05323   Rheumatoid arthritis oas05330   Allograft rejection oas05332   Graft-versus-host disease oas05410   Hypertrophic cardiomyopathy oas05414   Dilated cardiomyopathy oas05417   Lipid and atherosclerosis oas05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:oas00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     443540 (TNF)    04350 TGF-beta signaling pathway     443540 (TNF)    04064 NF-kappa B signaling pathway     443540 (TNF)    04668 TNF signaling pathway     443540 (TNF)    04071 Sphingolipid signaling pathway     443540 (TNF)    04150 mTOR signaling pathway     443540 (TNF)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     443540 (TNF)    04061 Viral protein interaction with cytokine and cytokine receptor     443540 (TNF)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     443540 (TNF)    04217 Necroptosis     443540 (TNF)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     443540 (TNF)    04620 Toll-like receptor signaling pathway     443540 (TNF)    04621 NOD-like receptor signaling pathway     443540 (TNF)    04622 RIG-I-like receptor signaling pathway     443540 (TNF)    04625 C-type lectin receptor signaling pathway     443540 (TNF)    04650 Natural killer cell mediated cytotoxicity     443540 (TNF)    04612 Antigen processing and presentation     443540 (TNF)    04660 T cell receptor signaling pathway     443540 (TNF)    04657 IL-17 signaling pathway     443540 (TNF)    04664 Fc epsilon RI signaling pathway     443540 (TNF)   09152 Endocrine system    04920 Adipocytokine signaling pathway     443540 (TNF)   09158 Development and regeneration    04380 Osteoclast differentiation     443540 (TNF)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     443540 (TNF)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     443540 (TNF)    05170 Human immunodeficiency virus 1 infection     443540 (TNF)    05161 Hepatitis B     443540 (TNF)    05160 Hepatitis C     443540 (TNF)    05171 Coronavirus disease - COVID-19     443540 (TNF)    05164 Influenza A     443540 (TNF)    05168 Herpes simplex virus 1 infection     443540 (TNF)    05163 Human cytomegalovirus infection     443540 (TNF)    05169 Epstein-Barr virus infection     443540 (TNF)    05165 Human papillomavirus infection     443540 (TNF)   09171 Infectious disease: bacterial    05132 Salmonella infection     443540 (TNF)    05135 Yersinia infection     443540 (TNF)    05133 Pertussis     443540 (TNF)    05134 Legionellosis     443540 (TNF)    05152 Tuberculosis     443540 (TNF)   09174 Infectious disease: parasitic    05146 Amoebiasis     443540 (TNF)    05144 Malaria     443540 (TNF)    05145 Toxoplasmosis     443540 (TNF)    05140 Leishmaniasis     443540 (TNF)    05142 Chagas disease     443540 (TNF)    05143 African trypanosomiasis     443540 (TNF)   09163 Immune disease    05310 Asthma     443540 (TNF)    05322 Systemic lupus erythematosus     443540 (TNF)    05323 Rheumatoid arthritis     443540 (TNF)    05321 Inflammatory bowel disease     443540 (TNF)    05330 Allograft rejection     443540 (TNF)    05332 Graft-versus-host disease     443540 (TNF)   09164 Neurodegenerative disease    05010 Alzheimer disease     443540 (TNF)    05014 Amyotrophic lateral sclerosis     443540 (TNF)    05020 Prion disease     443540 (TNF)    05022 Pathways of neurodegeneration - multiple diseases     443540 (TNF)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     443540 (TNF)    05418 Fluid shear stress and atherosclerosis     443540 (TNF)    05410 Hypertrophic cardiomyopathy     443540 (TNF)    05414 Dilated cardiomyopathy     443540 (TNF)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     443540 (TNF)    04940 Type I diabetes mellitus     443540 (TNF)    04936 Alcoholic liver disease     443540 (TNF)    04932 Non-alcoholic fatty liver disease     443540 (TNF)    04931 Insulin resistance     443540 (TNF)    04933 AGE-RAGE signaling pathway in diabetic complications     443540 (TNF)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     443540 (TNF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:oas04052]     443540 (TNF)    00536 Glycosaminoglycan binding proteins [BR:oas00536]     443540 (TNF) Cytokines and neuropeptides [BR:oas04052]  Cytokines   Tumor necrosis fators    443540 (TNF) Glycosaminoglycan binding proteins [BR:oas00536]  Heparan sulfate / Heparin   Cytokines    443540 (TNF) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  TNF Motif Other DBs NCBI-GeneID:  443540 NCBI-ProteinID:  NP_001020031 UniProt:  P23383 A5YBV0 LinkDB All DBs Position 20:complement(26798126..26800865) Genome browser AA seq 234 aa AA seqDB search MSTKSMIRDVELAEEVLSNKAGGPQGSRSCWCLSLFSFLLVAGATTLFCLLHFGVIGPQR EEQSPAGPSFNRPLVQTLRSSSQASNNKPVAHVVANISAPGQLRWGDSYANALMANGVEL KDNQLVVPTDGLYLIYSQVLFRGHGCPSTPLFLTHTISRIAVSYQTKVNILSAIKSPCHR ETLEGAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPEYLDYAESGQVYFGIIAL NT seq 705 nt NT seq  +upstreamnt  +downstreamnt atgagcaccaaaagcatgatccgggatgtggagctggcggaggaggtgctctccaacaaa gcagggggcccccagggctccagaagttgctggtgcctcagcctcttctccttcctcctg gttgcaggagccaccacgctcttctgcctgctgcacttcggggtaatcggcccccagagg gaagagcagtccccagctggcccctccttcaacaggcctctggttcagacactcaggtca tcttctcaagcctcaaataacaagccggtagcccacgttgtagccaacatcagcgctccg gggcagctccgatggggggactcgtatgccaatgccctcatggccaacggcgtggagctg aaagacaaccagctggtggtgcccactgacgggctttacctcatctactcgcaggtcctc ttcaggggccacggctgcccttccacccccttgttcctcacccacaccatcagccgcatt gcagtctcctaccagaccaaggtcaacatcctctctgccatcaagagcccttgccacagg gagaccctagagggggctgaggccaagccctggtacgaacccatctaccagggaggggtc ttccagctggagaagggagatcgcctcagtgctgagatcaacctgccggaatacctggac tatgccgagtctgggcaggtctactttgggatcatcgccctgtga

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