KEGG   Oreochromis aureus (blue tilapia): 116310020
Entry
116310020         CDS       T07295                                 
Symbol
map2k2a
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2a
  KO
K04369  mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
oau  Oreochromis aureus (blue tilapia)
Pathway
oau04010  MAPK signaling pathway
oau04012  ErbB signaling pathway
oau04068  FoxO signaling pathway
oau04140  Autophagy - animal
oau04148  Efferocytosis
oau04150  mTOR signaling pathway
oau04210  Apoptosis
oau04218  Cellular senescence
oau04270  Vascular smooth muscle contraction
oau04370  VEGF signaling pathway
oau04371  Apelin signaling pathway
oau04540  Gap junction
oau04620  Toll-like receptor signaling pathway
oau04810  Regulation of actin cytoskeleton
oau04910  Insulin signaling pathway
oau04912  GnRH signaling pathway
oau04916  Melanogenesis
oau05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:oau00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116310020 (map2k2a)
   04012 ErbB signaling pathway
    116310020 (map2k2a)
   04370 VEGF signaling pathway
    116310020 (map2k2a)
   04371 Apelin signaling pathway
    116310020 (map2k2a)
   04068 FoxO signaling pathway
    116310020 (map2k2a)
   04150 mTOR signaling pathway
    116310020 (map2k2a)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116310020 (map2k2a)
   04148 Efferocytosis
    116310020 (map2k2a)
  09143 Cell growth and death
   04210 Apoptosis
    116310020 (map2k2a)
   04218 Cellular senescence
    116310020 (map2k2a)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    116310020 (map2k2a)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116310020 (map2k2a)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    116310020 (map2k2a)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116310020 (map2k2a)
   04912 GnRH signaling pathway
    116310020 (map2k2a)
   04916 Melanogenesis
    116310020 (map2k2a)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    116310020 (map2k2a)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116310020 (map2k2a)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oau01001]
    116310020 (map2k2a)
Enzymes [BR:oau01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     116310020 (map2k2a)
Protein kinases [BR:oau01001]
 Serine/threonine kinases: STE group
  STE7 family
   116310020 (map2k2a)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7 APH Kdo
Other DBs
NCBI-GeneID: 116310020
NCBI-ProteinID: XP_031582602
Ensembl: ENSOABG00000016595
LinkDB
Position
LG23:complement(34625736..34637374)
AA seq 399 aa
MGPKRKPGPLNITPIGEGQATSNTIDAASEANLEALQKKLGELDLDEQQRKRLEAFLTQK
AQVGELKDEDFEPICELGAGNGGVVNKVRHKPSGLVMARKLIHLEIKPAIRNQIIRELQV
LHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEARRIPEEILGKVSIAVLRGL
AYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQG
THYSVQSDVWSMGLSLVELAIGRYPIPPPDARELEAIFGRAVMDGAEGEPHVNMQRPRPP
GRPISGSAMDSRPAMAIFELLDYIVNEPPPKLPLGVFTSDFQDFVTKCLIKNPAERADLK
MLMSHTFIKRSEVEEVDFAGWLCKTMGLNQPSTPTRGAE
NT seq 1200 nt   +upstreamnt  +downstreamnt
atgggccccaaaagaaaacccggtccccttaacattacgcccattggagagggacaggcc
acctccaacaccattgatgctgcatctgaagccaacctcgaggccttacagaagaagctg
ggggagctggacctggatgaacagcagaggaaacggctggaagcctttctcacccagaaa
gcccaggtcggggagctgaaggatgaagatttcgaacccatatgtgagctaggcgcagga
aacggaggggtggtcaacaaggtccgccacaaaccctcgggcttggtcatggctcggaag
ttgatccacctggaaatcaaacctgccatcagaaaccagattatcagagagctgcaggtc
cttcatgaatgcaactcaccctatattgtgggcttttatggggccttctacagcgatgga
gagatcagcatctgtatggagcacatggatggtggatccttggaccaggttcttaaggaa
gccagaagaatcccagaagaaatccttggaaaagttagcatagctgtgttgaggggattg
gcatatctgcgagagaagcaccagatcatgcacagagacgtcaagccctccaacatactg
gtcaactctcgtggggagatcaagctgtgcgacttcggtgttagcggccagctcatagat
tccatggccaactcctttgttggaacgcgctcctacatgtcgccggagagactgcagggc
actcattactcggttcagtctgacgtgtggagcatgggtctgtctctggtagagctggcg
attggccgctaccccatccccccaccagacgccagagaactggaggccatcttcggacgg
gccgttatggatggggctgagggagagcctcacgtcaacatgcagaggcctagaccaccc
ggaaggcctataagtggatctgcgatggacagtagacctgccatggccatctttgaactt
ttggactacattgtcaatgagccaccccccaaactgccgcttggtgtgttcaccagtgac
ttccaggactttgtgacaaaatgtttgattaaaaacccagctgagagagcagatctgaag
atgctcatgagtcacacattcatcaagcgatcagaagtggaggaagtggactttgctggc
tggttgtgcaaaaccatgggcctcaaccagcccagcactcccacccgcggcgccgagtga

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